M
Michael Boehnke
Researcher at University of Michigan
Publications - 540
Citations - 155551
Michael Boehnke is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Type 2 diabetes. The author has an hindex of 152, co-authored 511 publications receiving 136681 citations. Previous affiliations of Michael Boehnke include SUNY Downstate Medical Center & Norwegian University of Science and Technology.
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Journal ArticleDOI
Common variants associated with plasma triglycerides and risk for coronary artery disease
Ron Do,Cristen J. Willer,Ellen M. Schmidt,Sebanti Sengupta,Chi Gao,Gina M. Peloso,Stefan Gustafsson,Stavroula Kanoni,Andrea Ganna,Jin Chen,Martin L. Buchkovich,Samia Mora,Jacques S. Beckmann,Jennifer L. Bragg-Gresham,Hsing-Yi Chang,Ayse Demirkan,Heleen M. den Hertog,Louise A. Donnelly,Georg Ehret,Tõnu Esko,Mary F. Feitosa,Teresa Ferreira,Krista Fischer,Pierre Fontanillas,Ross M. Fraser,Daniel F. Freitag,Deepti Gurdasani,Kauko Heikkilä,Elina Hyppönen,Aaron Isaacs,Anne U. Jackson,Åsa Johansson,Toby Johnson,Marika Kaakinen,Johannes Kettunen,Johannes Kettunen,Marcus E. Kleber,Xiaohui Li,Jian'an Luan,Leo-Pekka Lyytikäinen,Patrik K. E. Magnusson,Massimo Mangino,Evelin Mihailov,May E. Montasser,Martina Müller-Nurasyid,Ilja M. Nolte,Jeffrey R. O'Connell,Cameron D. Palmer,Markus Perola,Ann-Kristin Petersen,Serena Sanna,Richa Saxena,Sonia Shah,Dmitry Shungin,Carlo Sidore,Ci Song,Rona J. Strawbridge,Ida Surakka,Ida Surakka,Toshiko Tanaka,Tanya M. Teslovich,Gudmar Thorleifsson,Evita G. Van Den Herik,Benjamin F. Voight,Kelly A. Volcik,Lindsay L. Waite,Andrew Wong,Ying Wu,Weihua Zhang,Devin Absher,Gershim Asiki,Inês Barroso,Latonya F. Been,Jennifer L. Bolton,Lori L. Bonnycastle,Paolo Brambilla,Mary Susan Burnett,Giancarlo Cesana,Maria Dimitriou,Alex S. F. Doney,Angela Döring,Paul Elliott,Stephen E. Epstein,Gudmundur I. Eyjolfsson,Bruna Gigante,Mark O. Goodarzi,Harald Grallert,Martha L. Gravito,Christopher J. Groves,Göran Hallmans,Anna-Liisa Hartikainen,Caroline Hayward,Dena G. Hernandez,Andrew A. Hicks,Hilma Holm,Yi Jen Hung,Thomas Illig,Matthew Jones,Pontiano Kaleebu,John J.P. Kastelein,Kay-Tee Khaw,Eric Kim,Norman Klopp,Pirjo Komulainen,Meena Kumari,Claudia Langenberg,Terho Lehtimäki,Shih-Yi Lin,Jaana Lindström,Ruth J. F. Loos,François Mach,Wendy L. McArdle,Christa Meisinger,Braxton D. Mitchell,Gabrielle Müller,Ramaiah Nagaraja,Narisu Narisu,Tuomo Nieminen,Rebecca N. Nsubuga,Isleifur Olafsson,Ken K. Ong,Aarno Palotie,Theodore Papamarkou,Cristina Pomilla,Anneli Pouta,Anneli Pouta,Daniel J. Rader,Muredach P. Reilly,Paul M. Ridker,Fernando Rivadeneira,Igor Rudan,Aimo Ruokonen,Nilesh J. Samani,Hubert Scharnagl,Janet Seeley,Kaisa Silander,Kaisa Silander,Alena Stančáková,Kathleen Stirrups,Amy J. Swift,Laurence Tiret,André G. Uitterlinden,L. Joost van Pelt,Sailaja Vedantam,Nicholas W.J. Wainwright,Cisca Wijmenga,Sarah H. Wild,Gonneke Willemsen,Tom Wilsgaard,James F. Wilson,Elizabeth H. Young,Jing Hua Zhao,Linda S. Adair,Dominique Arveiler,Themistocles L. Assimes,Stefania Bandinelli,Franklyn I. Bennett,Murielle Bochud,Bernhard O. Boehm,Dorret I. Boomsma,Ingrid B. Borecki,Stefan R. Bornstein,Pascal Bovet,Michel Burnier,Harry Campbell,Aravinda Chakravarti,John C. Chambers,Yii-Der Ida Chen,Francis S. Collins,Richard S. Cooper,John Danesh,George Dedoussis,Ulf de Faire,Alan B. Feranil,Jean Ferrières,Luigi Ferrucci,Nelson B. Freimer,Christian Gieger,Leif Groop,Vilmundur Gudnason,Ulf Gyllensten,Anders Hamsten,Tamara B. Harris,Aroon D. Hingorani,Joel N. Hirschhorn,Albert Hofman,G. Kees Hovingh,Chao A. Hsiung,Steve E. Humphries,Steven C. Hunt,Kristian Hveem,Carlos Iribarren,Marjo-Riitta Järvelin,Antti Jula,Mika Kähönen,Jaakko Kaprio,Jaakko Kaprio,Antero Kesäniemi,Mika Kivimäki,Jaspal S. Kooner,Peter J. Koudstaal,Ronald M. Krauss,Diana Kuh,Johanna Kuusisto,Kirsten Ohm Kyvik,Markku Laakso,Timo A. Lakka,Lars Lind,Cecilia M. Lindgren,Nicholas G. Martin,Winfried März,Mark I. McCarthy,Colin A. McKenzie,Pierre Meneton,Andres Metspalu,Leena Moilanen,Andrew D. Morris,Patricia B. Munroe,Inger Njølstad,Nancy L. Pedersen,Chris Power,Peter P. Pramstaller,Jackie F. Price,Bruce M. Psaty,Thomas Quertermous,Rainer Rauramaa,Danish Saleheen,Veikko Salomaa,Dharambir K. Sanghera,Jouko Saramies,Peter Schwarz,Wayne Huey-Herng Sheu,Alan R. Shuldiner,Agneta Siegbahn,Tim D. Spector,Kari Stefansson,David P. Strachan,Bamidele O. Tayo,Elena Tremoli,Jaakko Tuomilehto,Matti Uusitupa,Cornelia M. van Duijn,Peter Vollenweider,Lars Wallentin,Nicholas J. Wareham,John Whitfield,Bruce H. R. Wolffenbuttel,David Altshuler,Jose M. Ordovas,Eric Boerwinkle,Colin N. A. Palmer,Unnur Thorsteinsdottir,Daniel I. Chasman,Jerome I. Rotter,Paul W. Franks,Samuli Ripatti,L. Adrienne Cupples,Manjinder S. Sandhu,Stephen S. Rich,Michael Boehnke,Panos Deloukas,Karen L. Mohlke,Erik Ingelsson,Gonçalo R. Abecasis,Mark J. Daly,Benjamin M. Neale,Sekar Kathiresan +266 more
TL;DR: It is suggested that triglyceride-rich lipoproteins causally influence risk for CAD, and the strength of a polymorphism's effect on triglyceride levels is correlated with the magnitude of its effect on CAD risk.
Journal ArticleDOI
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Alisa K. Manning,Alisa K. Manning,Alisa K. Manning,Robert A. Scott,Jonna L. Grimsby,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Han Chen,Denis Rybin,Ching-Ti Liu,Lawrence F. Bielak,Inga Prokopenko,Najaf Amin,Daniel R. Barnes,Gemma Cadby,Gemma Cadby,Jouke-Jan Hottenga,Erik Ingelsson,Anne U. Jackson,Toby Johnson,Stavroula Kanoni,Claes Ladenvall,Vasiliki Lagou,Jari Lahti,Cécile Lecoeur,Cécile Lecoeur,Yongmei Liu,María Teresa Martínez-Larrad,May E. Montasser,Pau Navarro,John R. B. Perry,John R. B. Perry,John R. B. Perry,Laura J. Rasmussen-Torvik,Perttu Salo,Naveed Sattar,Dmitry Shungin,Dmitry Shungin,Rona J. Strawbridge,Toshiko Tanaka,Cornelia M. van Duijn,Ping An,Mariza de Andrade,Jeanette S. Andrews,Thor Aspelund,Mustafa Atalay,Yurii S. Aulchenko,Beverley Balkau,Stefania Bandinelli,Jacques S. Beckmann,John Beilby,Claire Bellis,Richard N. Bergman,John Blangero,Mladen Boban,Michael Boehnke,Eric Boerwinkle,Lori L. Bonnycastle,Dorret I. Boomsma,Ingrid B. Borecki,Yvonne Böttcher,Claude Bouchard,Eric J. Brunner,Danijela Budimir,Harry Campbell,Olga D. Carlson,Peter S. Chines,Robert Clarke,Francis S. Collins,Arturo Corbató-Anchuelo,David Couper,Ulf de Faire,George Dedoussis,Panos Deloukas,Maria Dimitriou,Josephine M. Egan,Gudny Eiriksdottir,Michael R. Erdos,Johan G. Eriksson,Elodie Eury,Elodie Eury,Luigi Ferrucci,Ian Ford,Nita G. Forouhi,Caroline S. Fox,Caroline S. Fox,Maria Grazia Franzosi,Paul W. Franks,Timothy M. Frayling,Philippe Froguel,Pilar Galan,Eco J. C. de Geus,Bruna Gigante,Nicole L. Glazer,Anuj Goel,Leif Groop,Vilmundur Gudnason,Göran Hallmans,Anders Hamsten,Ola Hansson,Tamara B. Harris,Caroline Hayward,Simon Heath,Serge Hercberg,Andrew A. Hicks,Aroon D. Hingorani,Albert Hofman,Jennie Hui,Joseph Hung,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Min A. Jhun,Paul C. D. Johnson,J. Wouter Jukema,Antti Jula,Wen Hong L. Kao,Jaakko Kaprio,Jaakko Kaprio,Sharon L.R. Kardia,Sirkka Keinänen-Kiukaanniemi,Mika Kivimäki,Ivana Kolcic,Peter Kovacs,Meena Kumari,Johanna Kuusisto,Kirsten Ohm Kyvik,Markku Laakso,Timo A. Lakka,Lars Lannfelt,G. Mark Lathrop,Lenore J. Launer,Karin Leander,Guo Li,Lars Lind,Jaana Lindström,Stéphane Lobbens,Stéphane Lobbens,Ruth J. F. Loos,Jian'an Luan,Valeriya Lyssenko,Reedik Mägi,Reedik Mägi,Patrik K. E. Magnusson,Michael Marmot,Pierre Meneton,Karen L. Mohlke,Vincent Mooser,Mario A. Morken,Iva Miljkovic,Narisu Narisu,Jeffrey R. O'Connell,Ken K. Ong,Ben A. Oostra,Lyle J. Palmer,Lyle J. Palmer,Aarno Palotie,Aarno Palotie,Aarno Palotie,James S. Pankow,John F. Peden,Nancy L. Pedersen,Marina Pehlić,Leena Peltonen,Leena Peltonen,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Marijana Peričić,Markus Perola,Louis Pérusse,Patricia A. Peyser,Ozren Polasek,Peter P. Pramstaller,Michael A. Province,Katri Räikkönen,Rainer Rauramaa,Emil Rehnberg,Kenneth Rice,Jerome I. Rotter,Igor Rudan,Igor Rudan,Aimo Ruokonen,Timo Saaristo,Maria Sabater-Lleal,Veikko Salomaa,David B. Savage,Richa Saxena,Richa Saxena,Peter Schwarz,Udo Seedorf,Bengt Sennblad,Manuel Serrano-Ríos,Alan R. Shuldiner,Eric J.G. Sijbrands,David S. Siscovick,Johannes H. Smit,Kerrin S. Small,Nicholas L. Smith,Nicholas L. Smith,Nicholas L. Smith,Albert V. Smith,Alena Stančáková,Kathleen Stirrups,Michael Stumvoll,Yan V. Sun,Amy J. Swift,Anke Tönjes,Jaakko Tuomilehto,Stella Trompet,André G. Uitterlinden,Matti Uusitupa,Max Vikström,Veronique Vitart,Marie-Claude Vohl,Benjamin F. Voight,Peter Vollenweider,Gerard Waeber,Dawn M. Waterworth,Hugh Watkins,Hugh Watkins,Eleanor Wheeler,Elisabeth Widen,Sarah H. Wild,Sara M. Willems,Gonneke Willemsen,James F. Wilson,Jacqueline C.M. Witteman,Alan F. Wright,Hanieh Yaghootkar,Diana Zelenika,Tatijana Zemunik,Lina Zgaga,Lina Zgaga,Nicholas J. Wareham,Mark I. McCarthy,Inês Barroso,Inês Barroso,Richard M. Watanabe,Jose C. Florez,Jose C. Florez,José Dupuis,José Dupuis,James B. Meigs,Claudia Langenberg +243 more
TL;DR: Six previously unknown loci associated with fasting insulin at P < 5 × 10−8 in combined discovery and follow-up analyses of 52 studies comprising up to 96,496 non-diabetic individuals are presented.
Journal ArticleDOI
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
Daniel Taliun,Daniel N. Harris,Michael D. Kessler,Jedidiah Carlson,Jedidiah Carlson,Zachary A. Szpiech,Raul Torres,Sarah A Gagliano Taliun,André Corvelo,Stephanie M. Gogarten,Hyun Min Kang,Achilleas N. Pitsillides,Jonathon LeFaive,Seung-been Lee,Xiaowen Tian,Brian L. Browning,Sayantan Das,Anne-Katrin Emde,Wayne E. Clarke,Douglas Loesch,Amol C. Shetty,Thomas W. Blackwell,Albert V. Smith,Quenna Wong,Xiaoming Liu,Matthew P. Conomos,Dean Bobo,François Aguet,Christine M. Albert,Alvaro Alonso,Kristin G. Ardlie,Dan E. Arking,Stella Aslibekyan,Paul L. Auer,John Barnard,R. Graham Barr,Lucas Barwick,Lewis C. Becker,Rebecca L. Beer,Emelia J. Benjamin,Lawrence F. Bielak,John Blangero,Michael Boehnke,Donald W. Bowden,Jennifer A. Brody,Esteban G. Burchard,Brian E. Cade,Brian E. Cade,James F. Casella,Brandon Chalazan,Daniel I. Chasman,Daniel I. Chasman,Yii-Der Ida Chen,Michael H. Cho,Seung Hoan Choi,Mina K. Chung,Mina K. Chung,Mina K. Chung,Clary B. Clish,Adolfo Correa,Joanne E. Curran,Brian Custer,Dawood Darbar,Michelle Daya,Mariza de Andrade,Dawn L. DeMeo,Susan K. Dutcher,Patrick T. Ellinor,Leslie S. Emery,Celeste Eng,Diane Fatkin,Diane Fatkin,Diane Fatkin,Tasha E. Fingerlin,Lukas Forer,Myriam Fornage,Nora Franceschini,Christian Fuchsberger,Stephanie M. Fullerton,Soren Germer,Mark T. Gladwin,Daniel J. Gottlieb,Daniel J. Gottlieb,Xiuqing Guo,Michael E. Hall,Jiang He,Nancy L. Heard-Costa,Susan R. Heckbert,Marguerite R. Irvin,Jill M. Johnsen,Andrew D. Johnson,Robert C. Kaplan,Sharon L.R. Kardia,Tanika N. Kelly,Shannon Kelly,Eimear E. Kenny,Douglas P. Kiel,Robert Klemmer,Barbara A. Konkle,Charles Kooperberg,Anna Köttgen,Anna Köttgen,Leslie A. Lange,Jessica Lasky-Su,Daniel Levy,Daniel Levy,Xihong Lin,Keng-Han Lin,Chunyu Liu,Ruth J. F. Loos,Lori Garman,Robert E. Gerszten,Steven A. Lubitz,Kathryn L. Lunetta,Angel C.Y. Mak,Ani Manichaikul,Alisa K. Manning,Alisa K. Manning,Rasika A. Mathias,David D. McManus,Stephen T. McGarvey,James B. Meigs,Deborah A. Meyers,Julie L. Mikulla,Mollie A. Minear,Braxton D. Mitchell,Braxton D. Mitchell,Sanghamitra Mohanty,May E. Montasser,Courtney G. Montgomery,Alanna C. Morrison,Joanne M. Murabito,Andrea Natale,Pradeep Natarajan,Sarah C. Nelson,Kari E. North,Jeffrey R. O'Connell,Nicholette D. Palmer,Nathan Pankratz,Gina M. Peloso,Patricia A. Peyser,Jacob Pleiness,Wendy S. Post,Bruce M. Psaty,D. C. Rao,Susan Redline,Susan Redline,Alexander P. Reiner,Alexander P. Reiner,Dan M. Roden,Jerome I. Rotter,Ingo Ruczinski,Chloé Sarnowski,Sebastian Schoenherr,David A. Schwartz,Jeong-Sun Seo,Sudha Seshadri,Vivien A. Sheehan,Wayne Huey-Herng Sheu,M. Benjamin Shoemaker,Nicholas L. Smith,Nicholas L. Smith,Nicholas L. Smith,Jennifer A. Smith,Nona Sotoodehnia,Adrienne M. Stilp,Weihong Tang,Kent D. Taylor,Marilyn J. Telen,Timothy A. Thornton,Russell P. Tracy,David Van Den Berg,Ramachandran S. Vasan,Karine A. Viaud-Martinez,Scott I. Vrieze,Daniel E. Weeks,Bruce S. Weir,Scott T. Weiss,Lu-Chen Weng,Cristen J. Willer,Yingze Zhang,Xutong Zhao,Donna K. Arnett,Allison E. Ashley-Koch,Kathleen C. Barnes,Eric Boerwinkle,Eric Boerwinkle,Stacey Gabriel,Richard A. Gibbs,Kenneth Rice,Stephen S. Rich,Edwin K. Silverman,Pankaj Qasba,Weiniu Gan,George J. Papanicolaou,Deborah A. Nickerson,Sharon R. Browning,Michael C. Zody,Sebastian Zöllner,James G. Wilson,L. Adrienne Cupples,Cathy C. Laurie,Cashell E. Jaquish,Ryan D. Hernandez,Timothy D. O’Connor,Gonçalo R. Abecasis +205 more
TL;DR: The Trans-Omics for Precision Medicine (TOPMed) project as discussed by the authors aims to elucidate the genetic architecture and biology of heart, lung, blood and sleep disorders, with the ultimate goal of improving diagnosis, treatment and prevention of these diseases.
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Iris M. Heid,Anne U. Jackson,Joshua C. Randall,Thomas W. Winkler,Lu Qi,Valgerdur Steinthorsdottir,Gudmar Thorleifsson,M. Carola Zillikens,Elizabeth K. Speliotes,Reedik Maegi,Tsegaselassie Workalemahu,Charles C. White,Nabila Bouatia-Naji,Tamara B. Harris,Sonja I. Berndt,Erik Ingelsson,Cristen J. Willer,Michael N. Weedon,Jian'an Luan,Sailaja Vedantam,Tõnu Esko,Tuomas O. Kilpelaeinen,Zoltán Kutalik,Shengxu Li,Keri L. Monda,Anna L. Dixon,Christopher Holmes,Lee M. Kaplan,Liming Liang,Josine L. Min,Miriam F. Moffatt,Cliona Molony,George Nicholson,Eric E. Schadt,Krina T. Zondervan,Mary F. Feitosa,Teresa Ferreira,Hana Lango Allen,Robert J. Weyant,Eleanor Wheeler,Andrew R. Wood,Karol Estrada,Michael E. Goddard,Guillaume Lettre,Massimo Mangino,Dale R. Nyholt,Shaun Purcell,Albert V. Smith,Peter M. Visscher,Jian Yang,Steven A. McCarroll,James Nemesh,Benjamin F. Voight,Devin Absher,Najaf Amin,Thor Aspelund,Lachlan J. M. Coin,Nicole L. Glazer,Caroline Hayward,Nancy L. Heard-Costa,Jouke-Jan Hottenga,Åsa Johansson,Toby Johnson,Marika Kaakinen,Karen Kapur,Shamika Ketkar,Joshua W. Knowles,Peter Kraft,Aldi T. Kraja,Claudia Lamina,Michael F. Leitzmann,Barbara McKnight,Andrew P. Morris,Ken K. Ong,John R. B. Perry,Marjolein J. Peters,Ozren Polasek,Inga Prokopenko,Nigel W. Rayner,Samuli Ripatti,Fernando Rivadeneira,Neil R. Robertson,Serena Sanna,Ulla Sovio,Ida Surakka,Alexander Teumer,Sophie van Wingerden,Veronique Vitart,Jing Hua Zhao,Christine Cavalcanti-Proença,Peter S. Chines,Eva Fisher,Jennifer R. Kulzer,Cécile Lecoeur,Narisu Narisu,Camilla H. Sandholt,Laura J. Scott,Kaisa Silander,Klaus Stark,Mari-Liis Tammesoo,Tanya M. Teslovich,Nicholas J. Timpson,Richard M. Watanabe,Ryan P. Welch,Daniel I. Chasman,Mark E. Cooper,John-Olov Jansson,Johannes Kettunen,Robert Lawrence,Niina Pellikka,Markus Perola,Liesbeth Vandenput,Helene Alavere,Peter Almgren,Larry D. Atwood,Amanda J. Bennett,Reiner Biffar,Lori L. Bonnycastle,Stefan R. Bornstein,Thomas A. Buchanan,Harry Campbell,Ian N.M. Day,Mariano Dei,Marcus Doerr,Paul Elliott,Michael R. Erdos,Johan G. Eriksson,Nelson B. Freimer,Mao Fu,Stefan Gaget,Eco J. C. de Geus,Anette P. Gjesing,Harald Grallert,Juergen Graessler,Christopher J. Groves,Candace Guiducci,Anna-Liisa Hartikainen,Neelam Hassanali,Aki S. Havulinna,Karl-Heinz Herzig,Andrew A. Hicks,Jennie Hui,Wilmar Igl,Pekka Jousilahti,Antti Jula,Eero Kajantie,Leena Kinnunen,Ivana Kolcic,Seppo Koskinen,Peter Kovacs,Heyo K. Kroemer,Vjekoslav Krzelj,Johanna Kuusisto,Kirsti Kvaløy,Jaana Laitinen,Olivier Lantieri,G. Mark Lathrop,Marja-Liisa Lokki,Robert Luben,Barbara Ludwig,Wendy L. McArdle,Anne Marie McCarthy,Mario A. Morken,Mari Nelis,Matt Neville,Guillaume Paré,Alex N. Parker,John F. Peden,Irene Pichler,Kirsi H. Pietiläinen,Carl G. P. Platou,Anneli Pouta,Martin Ridderstråle,Nilesh J. Samani,Jouko Saramies,Juha Sinisalo,Jan Smit,Rona J. Strawbridge,Heather M. Stringham,Amy J. Swift,Maris Teder-Laving,Brian Thomson,Gianluca Usala,Joyce B. J. van Meurs,Gert-Jan B. van Ommen,Vincent Vatin,Claudia B. Volpato,Henri Wallaschofski,G. Bragi Walters,Elisabeth Widen,Sarah H. Wild,Gonneke Willemsen,Daniel R. Witte,Lina Zgaga,Paavo Zitting,John Beilby,Alan L. James,Mika Kähönen,Terho Lehtimäki,Markku S. Nieminen,Claes Ohlsson,Lyle J. Palmer,Olli T. Raitakari,Paul M. Ridker,Michael Stumvoll,Anke Toenjes,Jorma Viikari,Beverley Balkau,Yoav Ben-Shlomo,Richard N. Bergman,Heiner Boeing,George Davey Smith,Shah Ebrahim,Philippe Froguel,Torben Hansen,Christian Hengstenberg,Kristian Hveem,Bo Isomaa,Torben Jørgensen,Fredrik Karpe,Kay-Tee Khaw,Markku Laakso,Debbie A Lawlor,Michel Marre,Thomas Meitinger,Andres Metspalu,Kristian Midthjell,Oluf Pedersen,Veikko Salomaa,Peter Schwarz,Tiinamaija Tuomi,Jaakko Tuomilehto,Timo T. Valle,Nicholas J. Wareham,Alice M. Arnold,Jacques S. Beckmann,Sven Bergmann,Eric Boerwinkle,Dorret I. Boomsma,Mark J. Caulfield,Francis S. Collins,Gudny Eiriksdottir,Vilmundur Gudnason,Ulf Gyllensten,Anders Hamsten,Andrew T. Hattersley,Albert Hofman,Frank B. Hu,Thomas Illig,Carlos Iribarren,Marjo-Riitta Järvelin,W. H. Linda Kao,Jaakko Kaprio,Lenore J. Launer,Patricia B. Munroe,Ben A. Oostra,Brenda W.J.H. Penninx,Peter P. Pramstaller,Bruce M. Psaty,Thomas Quertermous,Aila Rissanen,Igor Rudan,Alan R. Shuldiner,Nicole Soranzo,Tim D. Spector,Ann-Christine Syvänen,Manuela Uda,André G. Uitterlinden,Henry Voelzke,Peter Vollenweider,James F. Wilson,Jacqueline C. M. Witteman,Alan F. Wright,Gonçalo R. Abecasis,Michael Boehnke,Ingrid B. Borecki,Panos Deloukas,Timothy M. Frayling,Leif Groop,Talin Haritunians,David J. Hunter,Robert C. Kaplan,Kari E. North,Jeffrey R. O'Connell,Leena Peltonen,David Schlessinger,David P. Strachan,Joel N. Hirschhorn,Themistocles L. Assimes,H-Erich Wichmann,Unnur Thorsteinsdottir,Cornelia M. van Duijn,Kari Stefansson,L. Adrienne Cupples,Ruth J. F. Loos,Inês Barroso,Mark I. McCarthy,Caroline S. Fox,Karen L. Mohlke,Cecilia M. Lindgren +299 more
Journal ArticleDOI
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Robert A. Scott,Vasiliki Lagou,Ryan P. Welch,Eleanor Wheeler,May E. Montasser,Jian'an Luan,Reedik Mägi,Rona J. Strawbridge,Emil Rehnberg,Stefan Gustafsson,Stavroula Kanoni,Laura J. Rasmussen-Torvik,Loic Yengo,Cécile Lecoeur,Dmitry Shungin,Serena Sanna,Carlo Sidore,Paul C. D. Johnson,J. Wouter Jukema,Toby Johnson,Anubha Mahajan,Niek Verweij,Gudmar Thorleifsson,Jouke-Jan Hottenga,Sonia Shah,Albert V. Smith,Bengt Sennblad,Christian Gieger,Perttu Salo,Markus Perola,Nicholas J. Timpson,David M. Evans,Beate St Pourcain,Ying Wu,Jeanette S. Andrews,Jennie Hui,Lawrence F. Bielak,Wei Zhao,Momoko Horikoshi,Pau Navarro,Aaron Isaacs,Jeffrey R. O'Connell,Kathleen Stirrups,Veronique Vitart,Caroline Hayward,Tõnu Esko,Evelin Mihailov,Ross M. Fraser,Tove Fall,Benjamin F. Voight,Soumya Raychaudhuri,Han Chen,Cecilia M. Lindgren,Andrew P. Morris,Nigel W. Rayner,Neil Robertson,Denis Rybin,Ching-Ti Liu,Jacques S. Beckmann,Sara M. Willems,Peter S. Chines,Anne U. Jackson,Hyun Min Kang,Heather M. Stringham,Kijoung Song,Toshiko Tanaka,John F. Peden,Anuj Goel,Andrew A. Hicks,Ping An,Martina Müller-Nurasyid,Anders Franco-Cereceda,Lasse Folkersen,Letizia Marullo,Hanneke Jansen,Albertine J. Oldehinkel,Marcel Bruinenberg,James S. Pankow,Kari E. North,Nita G. Forouhi,Ruth J. F. Loos,Sarah Edkins,Tibor V. Varga,Göran Hallmans,Heikki Oksa,Mulas Antonella,Ramaiah Nagaraja,Stella Trompet,Ian Ford,Stephan J. L. Bakker,Augustine Kong,Meena Kumari,Bruna Gigante,Christian Herder,Patricia B. Munroe,Mark J. Caulfield,Jula Antti,Massimo Mangino,Kerrin S. Small,Iva Miljkovic,Yongmei Liu,Mustafa Atalay,Wieland Kiess,Alan James,Fernando Rivadeneira,André G. Uitterlinden,Colin N. A. Palmer,Alex S. F. Doney,Gonneke Willemsen,Johannes H. Smit,Susan Campbell,Ozren Polasek,Lori L. Bonnycastle,Serge Hercberg,Maria Dimitriou,Jennifer L. Bolton,Gerard R Fowkes,Peter Kovacs,Jaana Lindström,Tatijana Zemunik,Stefania Bandinelli,Sarah H. Wild,Hanneke Basart,Wolfgang Rathmann,Harald Grallert,Winfried Maerz,Marcus E. Kleber,Bernhard O. Boehm,Annette Peters,Peter P. Pramstaller,Michael A. Province,Ingrid B. Borecki,Nicholas D. Hastie,Igor Rudan,Harry Campbell,Hugh Watkins,Martin Farrall,Michael Stumvoll,Luigi Ferrucci,Dawn M. Waterworth,Richard N. Bergman,Francis S. Collins,Jaakko Tuomilehto,Richard M. Watanabe,Eco J. C. de Geus,Brenda W.J.H. Penninx,Albert Hofman,Ben A. Oostra,Bruce M. Psaty,Peter Vollenweider,James F. Wilson,Alan F. Wright,G. Kees Hovingh,Andres Metspalu,Matti Uusitupa,Patrik K. E. Magnusson,Kirsten Ohm Kyvik,Jaakko Kaprio,Jackie F. Price,George Dedoussis,Panos Deloukas,Pierre Meneton,Lars Lind,Michael Boehnke,Alan R. Shuldiner,Cornelia M. van Duijn,Andrew D. Morris,Anke Toenjes,Patricia A. Peyser,John Beilby,John Beilby,Antje Körner,Johanna Kuusisto,Markku Laakso,Stefan R. Bornstein,Peter Schwarz,Timo A. Lakka,Rainer Rauramaa,Linda S. Adair,George Davey Smith,Tim D. Spector,Thomas Illig,Ulf de Faire,Anders Hamsten,Vilmundur Gudnason,Mika Kivimäki,Aroon D. Hingorani,Sirkka Keinänen-Kiukaanniemi,T. Saaristo,Dorret I. Boomsma,Kari Stefansson,Pim van der Harst,Josée Dupuis,Nancy L. Pedersen,Naveed Sattar,Tamara B. Harris,Francesco Cucca,Samuli Ripatti,Veikko Salomaa,Karen L. Mohlke,Beverley Balkau,Philippe Froguel,Anneli Pouta,Marjo-Riitta Järvelin,Nicholas J. Wareham,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Mark I. McCarthy,Paul W. Franks,James B. Meigs,Tanya M. Teslovich,Jose C. Florez,Claudia Langenberg,Erik Ingelsson,Inga Prokopenko,Inês Barroso +216 more
TL;DR: Gene-based analyses identified further biologically plausible loci, suggesting that additional loci beyond those reaching genome-wide significance are likely to represent real associations and further functional analysis of these newly discovered loci will further improve the understanding of glycemic control.