Michael Boehnke

TL;DR: This multiancestry study recommends investigation of the possible benefits of screening for the G6PD genotype along with using HbA1c to diagnose T2D in populations of African ancestry or groups where G 6PD deficiency is common, and investigates the effect of genetic risk-scores comprised of erythrocytic or glycemic variants on incident diabetes prediction and on prevalent diabetes screening performance.

TL;DR: By assembling extensive data on continuous glycemic traits, this work has exposed the diverse mechanisms whereby type 2 diabetes risk variants impact disease predisposition.

TL;DR: This work has identified several families that show linkage between breast and/or ovarian cancer and genetic markers that flank BRCA1 and developed a protocol to address the many issues that arise in the delivery of these services.

TL;DR: Genetic linkage analysis on two BWS kindreds suggests that BWS defines a tumor-predisposition gene on 11p15.5, which is related to the Wilms tumor gene on11p13 or, alternatively, to growth factor genes on 11 p15.

TL;DR: This work modifications a likelihood-based method to infer the most likely relationship of a pair of putative sibs to consider all possible pairs of individuals in the sample, to test for additional relationships, to allow explicitly for genotyping error, and to include X-linked data.