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Paolo Aretini
Researcher at University of Pisa
Publications - 93
Citations - 2517
Paolo Aretini is an academic researcher from University of Pisa. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 24, co-authored 82 publications receiving 2018 citations.
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Journal ArticleDOI
Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).
Nasim Mavaddat,Daniel Barrowdale,Irene L. Andrulis,Susan M. Domchek,Diana Eccles,Heli Nevanlinna,Susan J. Ramus,Amanda B. Spurdle,Mark E. Robson,Mark E. Sherman,Anna Marie Mulligan,Fergus J. Couch,Christoph Engel,Lesley McGuffog,Sue Healey,Olga M. Sinilnikova,Melissa C. Southey,Mary Beth Terry,David E. Goldgar,Frances P. O'Malley,Esther M. John,Ramunas Janavicius,Laima Tihomirova,Thomas Hansen,Finn Cilius Nielsen,Ana Osorio,Alexandra V. Stavropoulou,Javier Benitez,Siranoush Manoukian,Bernard Peissel,Monica Barile,Sara Volorio,Barbara Pasini,Riccardo Dolcetti,Anna Laura Putignano,Laura Ottini,Paolo Radice,Ute Hamann,Muhammad Usman Rashid,Frans B. L. Hogervorst,Mieke Kriege,Rob B. van der Luijt,Susan Peock,Debra Frost,D. Gareth Evans,Carole Brewer,Lisa Walker,Mark T. Rogers,Lucy Side,C. E. Houghton,Jo Ellen Weaver,Andrew K. Godwin,Rita K. Schmutzler,Barbara Wappenschmidt,Alfons Meindl,Karin Kast,Norbert Arnold,Dieter Niederacher,Christian Sutter,Helmut Deissler,Doroteha Gadzicki,Sabine Preisler-Adams,Raymonda Varon-Mateeva,Ines Schönbuchner,Heidrun Gevensleben,Dominique Stoppa-Lyonnet,Muriel Belotti,Laure Barjhoux,Claudine Isaacs,Beth N. Peshkin,Trinidad Caldés,Miguel De Al Hoya,Carmen Cañadas,Tuomas Heikkinen,Päivi Heikkilä,Kristiina Aittomäki,Ignacio Blanco,Conxi Lázaro,Joan Brunet,Bjarni A. Agnarsson,Adalgeir Arason,Rosa B. Barkardottir,Martine Dumont,Jacques Simard,Marco Montagna,Simona Agata,Emma D'Andrea,Max Yan,Stephen B. Fox,Timothy R. Rebbeck,Wendy S. Rubinstein,Nadine Tung,Judy Garber,Xianshu Wang,Zachary S. Fredericksen,Vernon S. Pankratz,Noralane M. Lindor,Csilla Szabo,Kenneth Offit,Rita A. Sakr,Mia M. Gaudet,Christian F. Singer,Muy Kheng Tea,Christine Rappaport,Phuong L. Mai,Mark H. Greene,Anna P. Sokolenko,Evgeny N. Imyanitov,Amanda E. Toland,Leigha Senter,Kevin Sweet,Mads Thomassen,Anne-Marie Gerdes,Torben A Kruse,Maria A. Caligo,Paolo Aretini,Johanna Rantala,Anna Von Wachenfeld,Karin M. Henriksson,Linda Steele,Susan L. Neuhausen,Robert L. Nussbaum,Mary S. Beattie,Kunle Odunsi,Lara Sucheston,Simon A. Gayther,Katherine L. Nathanson,Jenny Gross,Christine Walsh,Beth Y. Karlan,Georgia Chenevix-Trench,Douglas F. Easton,Antonis C. Antoniou +132 more
TL;DR: Pathologic characteristics of BRCA1 and BRCa2 tumors may be useful for improving risk-prediction algorithms and informing clinical strategies for screening and prophylaxis.
Journal ArticleDOI
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.
Timothy R. Rebbeck,Nandita Mitra,Fei Wan,Olga M. Sinilnikova,Sue Healey,Lesley McGuffog,Sylvie Mazoyer,Georgia Chenevix-Trench,Douglas F. Easton,Antonis C. Antoniou,Katherine L. Nathanson,Yael Laitman,Anya Kushnir,Shani Paluch-Shimon,Raanan Berger,Jamal Zidan,Eitan Friedman,Hans Ehrencrona,Hans Ehrencrona,Marie Stenmark-Askmalm,Zakaria Einbeigi,Niklas Loman,Katja Harbst,Johanna Rantala,Beatrice Melin,Dezheng Huo,Olufunmilayo I. Olopade,Joyce Seldon,Patricia A. Ganz,Robert L. Nussbaum,Salina B. Chan,Kunle Odunsi,Simon A. Gayther,Susan M. Domchek,Banu Arun,Karen H. Lu,Gillian Mitchell,Gillian Mitchell,Beth Y. Karlan,Christine Walsh,Jenny Lester,Andrew K. Godwin,Harsh B. Pathak,Eric A. Ross,Mary B. Daly,Alice S. Whittemore,Esther M. John,Alexander Miron,Mary Beth Terry,Wendy K. Chung,David E. Goldgar,Saundra S. Buys,Ramūnas Janavičius,Laima Tihomirova,Nadine Tung,Cecilia M. Dorfling,Elizabeth J. van Rensburg,Linda Steele,Susan L. Neuhausen,Yuan Chun Ding,Bent Ejlertsen,Anne-Marie Gerdes,Thomas Hansen,Teresa Ramón y Cajal,Ana Osorio,Javier Benitez,Javier Godino,Maria-Isabel Tejada,Mercedes Durán,Jeffrey N. Weitzel,Kristie Bobolis,Sharon Sand,Annette Fontaine,Antonella Savarese,Barbara Pasini,Bernard Peissel,Bernardo Bonanni,Daniela Zaffaroni,Francesca Vignolo-Lutati,Giulietta Scuvera,Giuseppe Giannini,Loris Bernard,Maurizio Genuardi,Paolo Radice,Riccardo Dolcetti,Siranoush Manoukian,Valeria Pensotti,Viviana Gismondi,Drakoulis Yannoukakos,Florentia Fostira,Judy Garber,Diana Torres,Muhammad Usman Rashid,Ute Hamann,Susan Peock,Debra Frost,Radka Platte,D. Gareth Evans,Rosalind A. Eeles,Rosemarie Davidson,Diana Eccles,Trevor Cole,Jackie Cook,Carole Brewer,Shirley Hodgson,Patrick J. Morrison,Lisa Walker,Mary Porteous,M. John Kennedy,Louise Izatt,Julian Adlard,Alan Donaldson,Steve Ellis,Priyanka Sharma,Rita K. Schmutzler,Barbara Wappenschmidt,Alexandra Becker,Kerstin Rhiem,Eric Hahnen,Christoph Engel,Alfons Meindl,Stefanie Engert,Nina Ditsch,Norbert Arnold,Hans Jörg Plendl,Christoph Mundhenke,Dieter Niederacher,Markus C. Fleisch,Christian Sutter,Claus R. Bartram,Nicola Dikow,Shan Wang-Gohrke,Dorothea Gadzicki,Doris Steinemann,Karin Kast,Marit Beer,Raymonda Varon-Mateeva,Andrea Gehrig,Bernhard H. F. Weber,Dominique Stoppa-Lyonnet,Dominique Stoppa-Lyonnet,Claude Houdayer,Claude Houdayer,Muriel Belotti,Marion Gauthier-Villars,Francesca Damiola,Nadia Boutry-Kryza,Christine Lasset,Hagay Sobol,Jean-Philippe Peyrat,Danièle Muller,Jean-Pierre Fricker,Marie-Agnès Collonge-Rame,Isabelle Mortemousque,Catherine Noguès,Etienne Rouleau,Claudine Isaacs,Anne De Paepe,Bruce Poppe,Kathleen Claes,Kim De Leeneer,Marion Piedmonte,Gustavo C. Rodriguez,Katie Wakely,John F. Boggess,Stephanie V. Blank,Jack Basil,Masoud Azodi,Kelly-Anne Phillips,Kelly-Anne Phillips,Trinidad Caldés,Miguel de la Hoya,Atocha Romero,Heli Nevanlinna,Kristiina Aittomäki,Annemarie H. van der Hout,Frans B. L. Hogervorst,Senno Verhoef,J. Margriet Collée,Caroline Seynaeve,Jan C. Oosterwijk,Johannes J. P. Gille,Juul T. Wijnen,Encarna B. Gomez Garcia,Carolien M. Kets,Margreet G. E. M. Ausems,Cora M. Aalfs,Peter Devilee,Arjen R. Mensenkamp,Ava Kwong,Edith Olah,János Papp,Orland Diez,Conxi Lázaro,Esther Darder,Ignacio Blanco,Mónica Salinas,Anna Jakubowska,Jan Lubinski,Jacek Gronwald,Katarzyna Jaworska-Bieniek,Katarzyna Durda,Grzegorz Sukiennicki,Tomasz Huzarski,Tomasz Byrski,Cezary Cybulski,Aleksandra Tołoczko-Grabarek,Elżbieta Złowocka-Perłowska,Janusz Menkiszak,Adalgeir Arason,Rosa B. Barkardottir,Jacques Simard,Rachel Laframboise,Marco Montagna,Simona Agata,Elisa Alducci,Ana Peixoto,Manuel R. Teixeira,Amanda B. Spurdle,Min Hyuk Lee,Sue K. Park,Sung-Won Kim,Tara M. Friebel,Fergus J. Couch,Noralane M. Lindor,Vernon S. Pankratz,Lucia Guidugli,Xianshu Wang,Marc Tischkowitz,Marc Tischkowitz,Lenka Foretova,Joseph Vijai,Kenneth Offit,Mark E. Robson,Rohini Rau-Murthy,Noah D. Kauff,Anneliese Fink-Retter,Christian F. Singer,Christine Rappaport,Daphne Gschwantler-Kaulich,Georg Pfeiler,Muy-Kheng Tea,Andreas Berger,Mark H. Greene,Phuong L. Mai,Evgeny N. Imyanitov,Amanda E. Toland,Leigha Senter,Anders Bojesen,Inge Søkilde Pedersen,Anne-Bine Skytte,Lone Sunde,Mads Thomassen,Sanne Traasdahl Moeller,Torben A Kruse,Uffe Birk Jensen,Maria A. Caligo,Paolo Aretini,Soo Hwang Teo,Christina G. Selkirk,Peter J. Hulick,Irene L. Andrulis +261 more
TL;DR: In this paper, the relationship between specific mutations in BRCA1 and cancer risk has been investigated and limited information about the relationship has been available about specific mutations for specific mutations.
Journal ArticleDOI
Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study.
Cristian Scatena,Manuela Roncella,Antonello Di Paolo,Paolo Aretini,Michele Menicagli,Giovanni Fanelli,Carolina Marini,Chiara Maria Mazzanti,Matteo Ghilli,Federica Sotgia,Michael P. Lisanti,Antonio Giuseppe Naccarato +11 more
TL;DR: Quantitative decreases in CD44 and ALDH1 expression are consistent with pre-clinical experiments and suggest that doxycycline can selectively eradicate CSCs in breast cancer patients in vivo.
Journal ArticleDOI
KLF4 is a Novel Candidate Tumor Suppressor Gene in Pancreatic Ductal Carcinoma
Francesca Zammarchi,Mariangela Morelli,Michele Menicagli,Claudio Di Cristofano,Katia Zavaglia,Alessandra Paolucci,Daniela Campani,Paolo Aretini,Ugo Boggi,Franco Mosca,Andrea Cavazzana,Luca Cartegni,Generoso Bevilacqua,Chiara Maria Mazzanti +13 more
TL;DR: A novel oncosuppressor region located at the 9q 31.1-3 locus that is lost in DPC at high frequency is identified, suggesting a key suppressor role in pancreatic tumorigenesis.
Journal ArticleDOI
Angiogenesis and VEGF expression in pre-invasive lesions of the human breast.
Paolo Viacava,Antonio Giuseppe Naccarato,Guido Bocci,Giovanni Fanelli,Paolo Aretini,Antonino Lonobile,G Evangelista,Giancarlo Montruccoli,Generoso Bevilacqua +8 more
TL;DR: Angiogenesis and vascular endothelial growth factor expression were evaluated by immunohistochemistry in all types of human pre‐invasive breast lesion, un‐associated with invasive carcinoma, and VEGF expression in normal glandular structures was lower than in lesions, with the highest levels found in ductal lesions when compared with lobular lesions.