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Jack Basil

Researcher at Good Samaritan Hospital

Publications -  13
Citations -  1280

Jack Basil is an academic researcher from Good Samaritan Hospital. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 9, co-authored 12 publications receiving 1168 citations. Previous affiliations of Jack Basil include Ohio State University.

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Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

Timothy R. Rebbeck, +261 more
- 07 Apr 2015 - 
TL;DR: In this paper, the relationship between specific mutations in BRCA1 and cancer risk has been investigated and limited information about the relationship has been available about specific mutations for specific mutations.
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A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

Antonis C. Antoniou, +182 more
- 01 Oct 2010 - 
TL;DR: Five SNPs on 19p13 were associated with breast cancer risk and an association with estrogen receptor–positive disease in the opposite direction was identified andotyping these SNPs in 6,800 population-based breast cancer cases and 6,613 controls identified a similar association.
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Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

Antonis C. Antoniou, +184 more
- 01 Dec 2010 - 
TL;DR: In this article, the associations of three additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 in STXBP4/COX11, and rs10941679 at 5p12, were evaluated.
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Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

Antonis C. Antoniou, +138 more
TL;DR: The LSP1 and 2q35 SNPs appear to interact multiplicatively on breast cancer risk for BRCA2 mutation carriers and there was no evidence that the associations vary by mutation type depending on whether the mutated protein is predicted to be stable or not.