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Bandar A. Suliman

Researcher at Taibah University

Publications -  19
Citations -  860

Bandar A. Suliman is an academic researcher from Taibah University. The author has contributed to research in topics: Medicine & Transcription factor. The author has an hindex of 7, co-authored 16 publications receiving 616 citations. Previous affiliations of Bandar A. Suliman include Monash Institute of Medical Research & Hudson Institute of Medical Research.

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MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile.

TL;DR: A prominent pro‐inflammatory Th1 and Th17 response was clearly seen in patients with MERS‐CoV infection, with markedly increased concentrations of IFN‐&ggr;, TNF‐&agR;, IL‐15 and IL‐17 compared to controls.
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The promyelocytic leukemia zinc finger protein: two decades of molecular oncology

TL;DR: This review will examine the major advances in knowledge of PLZF biological activities that augment its value as a therapeutic target, particularly in cancer and immunological diseases.
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The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF

TL;DR: It is shown that signalling from Toll-like or TNF-α receptors triggers the calcium/calmodulin-dependent protein kinase (CaMK2) to activate histone acetyltransferase-1 (HAT1), which then acetylates the transcriptional regulator PLZF, which controls the inflammatory NF-κB transcriptional programme.
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Rare loss-of-function variants in type I IFN immunity genes are not associated with severe COVID-19

TL;DR: In this article, rare predicted loss-of-function (pLOF) variants across 13 candidate genes in TLR3- and IRF7-dependent type I IFN pathways explain up to 3.5% of severe COVID-19 cases.
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A first update on mapping the human genetic architecture of COVID-19

Gita A. Pathak, +822 more
- 04 Aug 2022 - 
TL;DR: A genome-wide association study meta-analysis of up to 125,584 cases and over 2.5 million control individuals across 60 studies from 25 countries reveals compelling insights regarding disease susceptibility and severity.