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Richard Bucala

Researcher at Yale University

Publications -  622
Citations -  58697

Richard Bucala is an academic researcher from Yale University. The author has contributed to research in topics: Macrophage migration inhibitory factor & Cytokine. The author has an hindex of 119, co-authored 595 publications receiving 54607 citations. Previous affiliations of Richard Bucala include École Polytechnique Fédérale de Lausanne & Rockefeller University.

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Blockade of macrophage migration inhibitory factor (MIF) in Schistosoma japonicum-infected mice results in an increased adult worm burden and reduced fecundity

Abram B. Stavitsky, +4 more
- 01 Jul 2003 - 
TL;DR: For the first time there is evidence that 4·5–6 week post‐infection endogenous MIF somehow mediates reduction of adult worm burden and promotes fecundity.
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Clinical patterns of juvenile idiopathic arthritis in Zambia

James Chipeta, +5 more
- 14 Sep 2013 - 
TL;DR: JIA is predominantly a polyarticular rheumatoid factor negative disease in Zambia and there is need to elucidate the genetics and environmental factors of JIA in this region.
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Nε-carboxymethyllysine formation by direct addition of glyoxal to lysine during the Maillard reaction

Yousef Al-Abed, +1 more
- 21 Sep 1995 - 
TL;DR: Glyoxal, a retro-aldol cleavage product of the Maillard reaction, is a likely intermediate for the formation of Ne-carboxymethyllysine upon incubation with lysine under physiological conditions.
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Structure of a synthetic glucose derived advanced glycation end product that is immunologically cross-reactive with its naturally occurring counterparts.

Yousef Al-Abed, +1 more
- 01 Jan 2000 - 
TL;DR: The properties of ALI, immunoreactivity, acid-lability, nonfluorescence, and inhibition of formation by aminoguanidine, suggest that ALI is likely to typify an important class of the AGE cross-links that form in vivo.
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Neurotoxicity of acetaldehyde-derived advanced glycation end products for cultured cortical neurons.

Masayoshi Takeuchi, +12 more
- 01 May 2003 - 
TL;DR: It is proposed that the structural epitope AA-AGE, one of the main metabolites of alcohol, is an important toxic moiety for neuronal cells in alcoholism and was detected in human brain of alcoholism.