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Richard Bucala

Researcher at Yale University

Publications -  622
Citations -  58697

Richard Bucala is an academic researcher from Yale University. The author has contributed to research in topics: Macrophage migration inhibitory factor & Cytokine. The author has an hindex of 119, co-authored 595 publications receiving 54607 citations. Previous affiliations of Richard Bucala include École Polytechnique Fédérale de Lausanne & Rockefeller University.

Papers
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Journal ArticleDOI

Brief report: Enhanced DRα1-mMOG-35-55 treatment of severe EAE in MIF-1-deficient male mice.

Arthur A. Vandenbark, +9 more
- 11 Sep 2021 - 
TL;DR: This article showed that deletion of MIF-1 resulted in a massive reduction in the expression of EAE- and Complete Freund's Adjuvant-associated inflammatory factors, suggesting delayed involvement of the MIF/CD74 axis in promoting disease expression.
Journal ArticleDOI

Rheumatology Forecast: Why Prevention Matters.

Richard Bucala
- 07 Apr 2020 - 
TL;DR: Analysis of the comparative prevalence of anti-nuclear antibody in three US cohorts sampled over a 25 year period finds that the disease is more common in those of African ancestry and in Asian populations.
Patent

Fibrocyte-based vaccine formulations

Glenn C. Rice, +1 more
TL;DR: In this paper, a method for establishing an immune response against a specific antigen by administering a fibrocyte-based vaccine formulation, such as one made by pulsing fibrogrocytes in culture with the antigen peptide or protein, or by fusing tumor cells (whole cells or membrane fragments thereof) with fibroglytes, was presented.

I-1 MIF, MIF Alleles, and the Regulation of the Host Response

Richard Bucala
TL;DR: Development of MIF alleles show significant population stratification, which may reflect the influence of selective pressure, and they likely provide an essential level of variation in innate responsiveness within the human population, integrated within the concept that MIF allele specific responses influence disease development.
Journal ArticleDOI

CD74 as a regulator of transcription in normal B cells.

K. David, +8 more
- 01 Nov 2022 - 
TL;DR: In this paper , the authors investigated the transcriptional and regulatory function of CD74-ICD in normal B cells and showed that following activation, CD74ICD forms a complex in the cytosol with transcription factors, like PAX5, and binds the chromatin at a significantly higher number of sites compared with its binding in CLL cells.