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Richard Bucala

Researcher at Yale University

Publications -  622
Citations -  58697

Richard Bucala is an academic researcher from Yale University. The author has contributed to research in topics: Macrophage migration inhibitory factor & Cytokine. The author has an hindex of 119, co-authored 595 publications receiving 54607 citations. Previous affiliations of Richard Bucala include École Polytechnique Fédérale de Lausanne & Rockefeller University.

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Filarial nematode parasites secrete a homologue of the human cytokine macrophage migration inhibitory factor.

Diana V. Pastrana, +8 more
- 01 Dec 1998 - 
TL;DR: It is reported that filarial parasites of humans secrete a homologue of the human proinflammatory cytokine macrophage migration inhibitory factor (MIF) that has the capability of modifying the activity of human monocytes/macrophages.
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Fibrocytes in health and disease

Erica L. Herzog, +1 more
- 01 Jul 2010 - 
TL;DR: Fibrocytes are circulating mesenchymal progenitor cells that participate in tissue responses to injury and invasion as discussed by the authors, and they are a biomarker for disease progression in chronic lung diseases including asthma and pulmonary fibrosis.
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Modification of DNA by reducing sugars: a possible mechanism for nucleic acid aging and age-related dysfunction in gene expression.

Richard Bucala, +2 more
- 01 Jan 1984 - 
TL;DR: It is concluded that glucose, Glc-6-P, and possibly other sugars can react with DNA to produce significant structural and biological alterations.
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MIF rediscovered: cytokine, pituitary hormone, and glucocorticoid-induced regulator of the immune response.

Richard Bucala
- 01 Dec 1996 - 
TL;DR: Observations suggest that MIF fills an important gap in how the host initiates and controls immunity, and is to act at an inflammatory site or lymph node to counterbalance the profound inhibitory effects of steroids on the immune response.
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Insulin secretion is regulated by the glucose-dependent production of islet β cell macrophage migration inhibitory factor

Gérard Waeber, +12 more
- 29 Apr 1997 - 
TL;DR: Macrophage migration inhibitory factor is reported here that the insulin-secreting beta cell of the islets of Langerhans expresses MIF and that its production is regulated by glucose in a time- and concentration-dependent manner.