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Richard Bucala

Researcher at Yale University

Publications -  622
Citations -  58697

Richard Bucala is an academic researcher from Yale University. The author has contributed to research in topics: Macrophage migration inhibitory factor & Cytokine. The author has an hindex of 119, co-authored 595 publications receiving 54607 citations. Previous affiliations of Richard Bucala include École Polytechnique Fédérale de Lausanne & Rockefeller University.

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Distribution maps of D-dopachrome tautomerase in the mouse brain.

TL;DR: The results show that D-dopachrome tautomerase is present throughout the brain parenchyma with a large fraction of heterogeneous interneurons harboring a stable and robust expression of the enzyme, and suggest some functional and evolutionary relationship between innate immunity and tautomersization of D-dupachrome in mammalian species.
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Macrophage migration inhibitory factor anti-thrombin III complexes are decreased in bladder cancer patient serum: Complex formation as a mechanism of inactivation.

TL;DR: Serum MIF in bladder cancer patients (TCC stage II, n=50) was increased when compared to normal patients, while ATIII-MIF complexes were decreased in bladder cancers patient serum, which suggest that increased circulating levels of bioactive MIF are present in bladdercancer patient serum.
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Role of Host and Parasite MIF Cytokines during Leishmania Infection.

TL;DR: The immune response to Leishmania in mouse models and humans will be reviewed, and the properties and activities of mammalian and Leishmaniasis MIF will be integrated into the current understandings in this field.