scispace - formally typeset
J

Janie F. Shelton

Researcher at University of Pittsburgh

Publications -  23
Citations -  2970

Janie F. Shelton is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Genome-wide association study & Medicine. The author has an hindex of 11, co-authored 12 publications receiving 1356 citations.

Papers
More filters
Journal ArticleDOI

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Mike A. Nalls, +248 more
- 01 Dec 2019 - 
TL;DR: These data provide the most comprehensive survey of genetic risk within Parkinson's disease to date, providing a biological context for these risk factors, and showing that a considerable genetic component of this disease remains unidentified.
Journal ArticleDOI

Genetic mechanisms of critical illness in Covid-19.

Erola Pairo-Castineira, +1449 more
- 04 Mar 2021 - 
TL;DR: The GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2244 critically ill Covid-19 patients from 208 UK intensive care units is reported, finding evidence in support of a causal link from low expression of IFNAR2, and high expression of TYK2, to life-threatening disease.

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Richard Karlsson Linnér, +387 more
TL;DR: A genetic study identifies hundreds of loci associated with risk tolerance and risky behaviors, finds evidence of substantial shared genetic influences across these phenotypes, and implicates genes involved in neurotransmission.
Journal ArticleDOI

Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity.

TL;DR: In this paper, a study of 1,051,032 23andMe research participants was conducted to identify genetic and nongenetic associations with testing positive for SARS-CoV-2, respiratory symptoms and hospitalization.
Journal ArticleDOI

Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

Aysu Okbay, +294 more
- 31 Mar 2022 - 
TL;DR: This paper conducted a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identified 3,952 approximately uncorrelated single-nucleotide polymorphisms (SNPs).