Hong Kong Baptist University

About: Hong Kong Baptist University is a education organization based out in Hong Kong, China. It is known for research contribution in the topics: China & Population. The organization has 7811 authors who have published 18919 publications receiving 555274 citations. The organization is also known as: Hong Kong Baptist College & HKBU.

New Design Tactics in OLEDs Using Functionalized 2‐Phenylpyridine‐Type Cyclometalates of Iridium(III) and Platinum(II)

Abstract: As a result of their outstanding attributes, organic light-emitting diodes (OLEDs) and white organic light-emitting diodes (WOLEDs) have been recognized in recent years as the most promising candidates for future flat-panel display technologies and next generation solid-state energy-saving lighting sources New advancements in the area of high performance triplet emitters become vital for realizing more practical applications In this regard, several critical issues must be carefully identified and addressed, and these include the ways to enhance device efficiency and suppress efficiency roll-off, to achieve versatile color tuning and simple device manufacture, as well as to obtain high-quality white light from WOLEDs It has been shown that some functionalized phosphorescent Ir(III) and Pt(II) ppy-type cyclometalated complexes (ppy = 2-phenylpyridine) possess unique features that are suitable for solving these difficult and challenging tasks In this Focus Review, we will highlight the recent design tactics adopted for these functional metallophosphors and the critical roles they may play in developing more realistic devices

Action2Activity: Recognizing Complex Activities from Sensor Data

Abstract: As compared to simple actions, activities are much more complex, but semantically consistent with a human's real life. Techniques for action recognition from sensor generated data are mature. However, there has been relatively little work on bridging the gap between actions and activities. To this end, this paper presents a novel approach for complex activity recognition comprising of two components. The first component is temporal pattern mining, which provides a mid-level feature representation for activities, encodes temporal relatedness among actions, and captures the intrinsic properties of activities. The second component is adaptive Multi-Task Learning, which captures relatedness among activities and selects discriminant features. Extensive experiments on a real-world dataset demonstrate the effectiveness of our work.

Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism.

Abstract: Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associated with bile-salt hydrolase (BSH) activity. Theabrownin increases the levels of ileal conjugated bile acids (BAs) which, in turn, inhibit the intestinal FXR-FGF15 signaling pathway, resulting in increased hepatic production and fecal excretion of BAs, reduced hepatic cholesterol, and decreased lipogenesis. The inhibition of intestinal FXR-FGF15 signaling is accompanied by increased gene expression of enzymes in the alternative BA synthetic pathway, production of hepatic chenodeoxycholic acid, activation of hepatic FXR, and hepatic lipolysis. Our results shed light into the mechanisms behind the cholesterol- and lipid-lowering effects of Pu-erh tea, and suggest that decreased intestinal BSH microbes and/or decreased FXR-FGF15 signaling may be potential anti-hypercholesterolemia and anti-hyperlipidemia therapies. Pu-erh tea displays cholesterol-lowering properties. Here, Huang et al. show that this is mostly due to the action of a pigment in Pu-erh tea that induces changes in certain gut microbiota and bile acid levels, thus modulating the gut-liver metabolic axis.