Institution
James Cook University
Education•Townsville, Queensland, Australia•
About: James Cook University is a education organization based out in Townsville, Queensland, Australia. It is known for research contribution in the topics: Population & Coral reef. The organization has 9101 authors who have published 27750 publications receiving 1032608 citations. The organization is also known as: JCU.
Topics: Population, Coral reef, Reef, Coral, Coral reef fish
Papers published on a yearly basis
Papers
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TL;DR: A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent and significant loci and finds important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia.
Abstract: Major depressive disorder (MDD) is a common illness accompanied by considerable morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide association meta-analysis based in 135,458 cases and 344,901 controls and identified 44 independent and significant loci. The genetic findings were associated with clinical features of major depression and implicated brain regions exhibiting anatomical differences in cases. Targets of antidepressant medications and genes involved in gene splicing were enriched for smaller association signal. We found important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia: lower educational attainment and higher body mass were putatively causal, whereas major depression and schizophrenia reflected a partly shared biological etiology. All humans carry lesser or greater numbers of genetic risk factors for major depression. These findings help refine the basis of major depression and imply that a continuous measure of risk underlies the clinical phenotype.
1,898 citations
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TL;DR: Experimental data support the conclusion that cutaneous chytridiomycosis is a fatal disease of anurans, and it is hypothesize that it is the proximate cause of these recent amphibian declines.
Abstract: Epidermal changes caused by a chytridiomycete fungus (Chytridiomycota; Chytridiales) were found in sick and dead adult anurans collected from montane rain forests in Queensland (Australia) and Panama during mass mortality events associated with significant population declines. We also have found this new disease associated with morbidity and mortality in wild and captive anurans from additional locations in Australia and Central America. This is the first report of parasitism of a vertebrate by a member of the phylum Chytridiomycota. Experimental data support the conclusion that cutaneous chytridiomycosis is a fatal disease of anurans, and we hypothesize that it is the proximate cause of these recent amphibian declines.
1,872 citations
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University of Western Sydney1, University of Ulm2, University of Tasmania3, Institut national de la recherche agronomique4, Blaise Pascal University5, University of Bordeaux6, Brown University7, National University of Patagonia San Juan Bosco8, James Cook University9, Macquarie University10, University of Alberta11, California State University, Bakersfield12, Leiden University13, University of Guelph14, University of Innsbruck15, University of Edinburgh16, Commonwealth Scientific and Industrial Research Organisation17, University of Trieste18, University of California, Santa Cruz19, University of Utah20, George Washington University21, Missouri Botanical Garden22
TL;DR: In this article, the authors draw together published and unpublished data on the vulnerability of the transport system to drought-induced embolism for a large number of woody species, with a view to examining the likely consequences of climate change for forest biomes.
Abstract: Shifts in rainfall patterns and increasing temperatures associated with climate change are likely to cause widespread forest decline in regions where droughts are predicted to increase in duration and severity(1). One primary cause of productivity loss and plant mortality during drought is hydraulic failure(2-4). Drought stress creates trapped gas emboli in the water transport system, which reduces the ability of plants to supply water to leaves for photosynthetic gas exchange and can ultimately result in desiccation and mortality. At present we lack a clear picture of how thresholds to hydraulic failure vary across a broad range of species and environments, despite many individual experiments. Here we draw together published and unpublished data on the vulnerability of the transport system to drought-induced embolism for a large number of woody species, with a view to examining the likely consequences of climate change for forest biomes. We show that 70% of 226 forest species from 81 sites worldwide operate with narrow (<1 megapascal) hydraulic safety margins against injurious levels of drought stress and therefore potentially face long-term reductions in productivity and survival if temperature and aridity increase as predicted for many regions across the globe(5,6). Safety margins are largely independent of mean annual precipitation, showing that there is global convergence in the vulnerability of forests to drought, with all forest biomes equally vulnerable to hydraulic failure regardless of their current rainfall environment. These findings provide insight into why drought-induced forest decline is occurring not only in arid regions but also in wet forests not normally considered at drought risk(7,8).
1,864 citations
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TL;DR: Records are compiled, extending back thousands of years, of the status and trends of seven major guilds of carnivores, herbivores, and architectural species from 14 regions that indicate reefs will not survive without immediate protection from human exploitation over large spatial scales.
Abstract: Degradation of coral reef ecosystems began centuries ago, but there is no global summary of the magnitude of change. We compiled records, extending back thousands of years, of the status and trends of seven major guilds of carnivores, herbivores, and architectural species from 14 regions. Large animals declined before small animals and architectural species, and Atlantic reefs declined before reefs in the Red Sea and Australia, but the trajectories of decline were markedly similar worldwide. All reefs were substantially degraded long before outbreaks of coral disease and bleaching. Regardless of these new threats, reefs will not survive without immediate protection from human exploitation over large spatial scales.
1,836 citations
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Mohammad H. Forouzanfar1, Lily Alexander1, H. Ross Anderson2, Victoria F Bachman1 +718 more•Institutions (295)
TL;DR: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) as mentioned in this paper provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution.
1,656 citations
Authors
Showing all 9184 results
Name | H-index | Papers | Citations |
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Christopher J L Murray | 209 | 754 | 310329 |
Hui-Ming Cheng | 147 | 880 | 111921 |
Joseph T. Hupp | 141 | 731 | 82647 |
Graeme J. Hankey | 137 | 844 | 143373 |
Bryan R. Cullen | 121 | 371 | 50901 |
Thomas J. Meyer | 120 | 1078 | 68519 |
William F. Laurance | 118 | 470 | 56464 |
Staffan Kjelleberg | 114 | 425 | 44414 |
Mike Clarke | 113 | 1037 | 164328 |
Gao Qing Lu | 108 | 546 | 53914 |
David J. Williams | 107 | 2060 | 62440 |
Tim J Peters | 106 | 1037 | 47394 |
Michael E. Goddard | 106 | 424 | 67681 |
Ove Hoegh-Guldberg | 106 | 425 | 63750 |
John C. Avise | 105 | 413 | 53088 |