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Showing papers by "Lawrence Berkeley National Laboratory published in 2003"


Journal ArticleDOI
TL;DR: A review of the most recent ARPES results on the cuprate superconductors and their insulating parent and sister compounds is presented in this article, with the purpose of providing an updated summary of the extensive literature.
Abstract: The last decade witnessed significant progress in angle-resolved photoemission spectroscopy (ARPES) and its applications. Today, ARPES experiments with 2-meV energy resolution and $0.2\ifmmode^\circ\else\textdegree\fi{}$ angular resolution are a reality even for photoemission on solids. These technological advances and the improved sample quality have enabled ARPES to emerge as a leading tool in the investigation of the high-${T}_{c}$ superconductors. This paper reviews the most recent ARPES results on the cuprate superconductors and their insulating parent and sister compounds, with the purpose of providing an updated summary of the extensive literature. The low-energy excitations are discussed with emphasis on some of the most relevant issues, such as the Fermi surface and remnant Fermi surface, the superconducting gap, the pseudogap and $d$-wave-like dispersion, evidence of electronic inhomogeneity and nanoscale phase separation, the emergence of coherent quasiparticles through the superconducting transition, and many-body effects in the one-particle spectral function due to the interaction of the charge with magnetic and/or lattice degrees of freedom. Given the dynamic nature of the field, we chose to focus mainly on reviewing the experimental data, as on the experimental side a general consensus has been reached, whereas interpretations and related theoretical models can vary significantly. The first part of the paper introduces photoemission spectroscopy in the context of strongly interacting systems, along with an update on the state-of-the-art instrumentation. The second part provides an overview of the scientific issues relevant to the investigation of the low-energy electronic structure by ARPES. The rest of the paper is devoted to the experimental results from the cuprates, and the discussion is organized along conceptual lines: normal-state electronic structure, interlayer interaction, superconducting gap, coherent superconducting peak, pseudogap, electron self-energy, and collective modes. Within each topic, ARPES data from the various copper oxides are presented.

3,077 citations


Journal ArticleDOI
14 Mar 2003-Science
TL;DR: Advances in characterization methods have led to a molecular-level understanding of the relationships between nanoparticle properties and catalytic performance, and this knowledge is contributing to the design and development of new catalysts.
Abstract: Most catalysts consist of nanometer-sized particles dispersed on a high-surface-area support. Advances in characterization methods have led to a molecular-level understanding of the relationships between nanoparticle properties and catalytic performance. Together with novel approaches to nanoparticle synthesis, this knowledge is contributing to the design and development of new catalysts.

2,243 citations


Journal ArticleDOI
TL;DR: The extent to which precision distance-redshift observations can map out the recent expansion history of the universe, including the acceleration-deceleration transition, and the components and equations of state of the energy density is examined.
Abstract: Exploring the recent expansion history of the universe promises insights into the cosmological model, the nature of dark energy, and potentially clues to high energy physics theories and gravitation. We examine the extent to which precision distance-redshift observations can map out the history, including the acceleration-deceleration transition, and the components and equations of state of the energy density. We consider the ability to distinguish between various dynamical scalar field models for the dark energy, as well as higher dimension and alternate gravity theories. Finally, we present a new, advantageous parametrization for the study of dark energy.

2,003 citations


Journal ArticleDOI
TL;DR: RHESSI as discussed by the authors is a Principal Investigator (PI) mission, where the PI is responsible for all aspects of the mission except the launch vehicle, and is designed to investigate particle acceleration and energy release in solar flares, through imaging and spectroscopy of hard X-ray/gamma-ray continua emitted by energetic electrons, and of gamma-ray lines produced by energetic ions.
Abstract: RHESSI is the sixth in the NASA line of Small Explorer (SMEX) missions and the first managed in the Principal Investigator mode, where the PI is responsible for all aspects of the mission except the launch vehicle. RHESSI is designed to investigate particle acceleration and energy release in solar flares, through imaging and spectroscopy of hard X-ray/gamma-ray continua emitted by energetic electrons, and of gamma-ray lines produced by energetic ions. The single instrument consists of an imager, made up of nine bi-grid rotating modulation collimators (RMCs), in front of a spectrometer with nine cryogenically-cooled germanium detectors (GeDs), one behind each RMC. It provides the first high-resolution hard X-ray imaging spectroscopy, the first high-resolution gamma-ray line spectroscopy, and the first imaging above 100 keV including the first imaging of gamma-ray lines. The spatial resolution is as fine as ~ 2.3 arc sec with a full-Sun (≳ 1°) field of view, and the spectral resolution is ~ 1–10 keV FWHM over the energy range from soft X-rays (3 keV) to gamma-rays (17 MeV). An automated shutter system allows a wide dynamic range (> 107) of flare intensities to be handled without instrument saturation. Data for every photon is stored in a solid-state memory and telemetered to the ground, thus allowing for versatile data analysis keyed to specific science objectives. The spin-stabilized (~ 15 rpm) spacecraft is Sun-pointing to within ~ 0.2° and operates autonomously. RHESSI was launched on 5 February 2002, into a nearly circular, 38° inclination, 600-km altitude orbit and began observations a week later. The mission is operated from Berkeley using a dedicated 11-m antenna for telemetry reception and command uplinks. All data and analysis software are made freely and immediately available to the scientific community.

1,991 citations


Journal ArticleDOI
TL;DR: In this paper, a set of high-redshift supernovae were used to confirm previous supernova evidence for an accelerating universe, and the supernova results were combined with independent flat-universe measurements of the mass density from CMB and galaxy redshift distortion data, they provided a measurement of $w=-1.05^{+0.15}-0.09$ if w is assumed to be constant in time.
Abstract: We report measurements of $\Omega_M$, $\Omega_\Lambda$, and w from eleven supernovae at z=0.36-0.86 with high-quality lightcurves measured using WFPC-2 on the HST. This is an independent set of high-redshift supernovae that confirms previous supernova evidence for an accelerating Universe. Combined with earlier Supernova Cosmology Project data, the new supernovae yield a flat-universe measurement of the mass density $\Omega_M=0.25^{+0.07}_{-0.06}$ (statistical) $\pm0.04$ (identified systematics), or equivalently, a cosmological constant of $\Omega_\Lambda=0.75^{+0.06}_{-0.07}$ (statistical) $\pm0.04$ (identified systematics). When the supernova results are combined with independent flat-universe measurements of $\Omega_M$ from CMB and galaxy redshift distortion data, they provide a measurement of $w=-1.05^{+0.15}_{-0.20}$ (statistical) $\pm0.09$ (identified systematic), if w is assumed to be constant in time. The new data offer greatly improved color measurements of the high-redshift supernovae, and hence improved host-galaxy extinction estimates. These extinction measurements show no anomalous negative E(B-V) at high redshift. The precision of the measurements is such that it is possible to perform a host-galaxy extinction correction directly for individual supernovae without any assumptions or priors on the parent E(B-V) distribution. Our cosmological fits using full extinction corrections confirm that dark energy is required with $P(\Omega_\Lambda>0)>0.99$, a result consistent with previous and current supernova analyses which rely upon the identification of a low-extinction subset or prior assumptions concerning the intrinsic extinction distribution.

1,687 citations


Journal ArticleDOI
TL;DR: A low-temperature, large-scale, and versatile synthetic process is needed before ZnO nanowire arrays find realistic applications in solar energy conversion, light emission, and other promising areas, and the ease of commercial scale-up is presented.
Abstract: Since the first report of ultraviolet lasing from ZnO nanowires, substantial effort has been devoted to the development of synthetic methodologies for one-dimensional ZnO nanostructures. Among the various techniques described in the literature, evaporation and condensation processes are favored for their simplicity and high-quality products, but these gas-phase approaches generally require economically prohibitive temperatures of 800–900 8C. Despite recent MOCVD schemes that reduced the deposition temperature to 450 8C by using organometallic zinc precursors, the commercial potential of gas-phase-grown ZnO nanowires remains constrained by the expensive and/or insulating (for example, Al2O3) substrates required for oriented growth, as well as the size and cost of the vapor deposition systems. A low-temperature, large-scale, and versatile synthetic process is needed before ZnO nanowire arrays find realistic applications in solar energy conversion, light emission, and other promising areas. Solution approaches to ZnO nanowires are appealing because of their low growth temperatures and good potential for scale-up. In this regard, Vayssieres et al. developed a hydrothermal process for producing arrays of ZnO microrods and nanorods on conducting glass substrates at 95 8C. Recently, a seeded growth process was used to make helical ZnO rods and columns at a similar temperature. Here we expand on these synthetic methods to produce homogeneous and dense arrays of ZnO nanowires that can be grown on arbitrary substrates under mild aqueous conditions. We present data for arrays on four-inch (ca. 10 cm) silicon wafers and two-inch plastic substrates, which demonstrate the ease of commercial scale-up. The simple two-step procedure yields oriented nanowire films with the largest surface area yet reported for nanowire arrays. The growth process ensures that a majority of the nanowires in the array are in direct contact with the substrate and provide a continuous pathway for carrier transport, an important feature for future electronic devices based on these materials. Well-aligned ZnO nanowire arrays were grown using a simple two-step process. In the first step, ZnO nanocrystals (5–10 nm in diameter) were spin-cast several times onto a four-inch Si(100) wafer to form a 50–200-nm thick film of crystal seeds. Between coatings, the wafer was annealed at 150 8C to ensure particle adhesion to the wafer surface. The ZnO nanocrystals were prepared according to the method of Pacholski. A NaOH solution in methanol (0.03m) was added slowly to a solution of zinc acetate dihydrate (0.01m) in methanol at 60 8C and stirred for two hours. The resulting nanoparticles are spherical and stable for at least two weeks in solution. After uniformly coating the silicon wafer with ZnO nanocrystals, hydrothermal ZnO growth was carried out by suspending the wafer upside-down in an open crystallizing dish filled with an aqueous solution of zinc nitrate hydrate (0.025m) and methenamine or diethylenetriamine (0.025m) at 90 8C. Reaction times spanned from 0.5 to 6 h. The wafer was then removed from solution, rinsed with deionized water, and dried. A field-emission scanning electron microscope (FESEM) was used to examine the morphology of the nanowire array across the entire wafer, while single nanowires were characterized by transmission electron microscopy (TEM). Nanowire crystallinity and growth direction were analyzed by X-ray diffraction and electron diffraction techniques. SEM images taken of several four-inch samples showed that the entire wafer was coated with a highly uniform and densely packed array of ZnO nanowires (Figure 1). X-ray diffraction (not shown) gave a wurtzite ZnO pattern with an enhanced (002) peak resulting from the vertical orientation of the nanowires. A typical synthesis (1.5 h) yielded wires with diameters ranging between 40–80 nm and lengths of 1.5–2 mm.

1,676 citations


Journal ArticleDOI
TL;DR: It is demonstrated that polytypism, or the existence of two or more crystal structures in different domains of the same crystal, coupled with the manipulation of surface energy at the nanoscale, can be exploited to produce branched inorganic nanostructures controllably.
Abstract: Nanoscale materials are currently being exploited as active components in a wide range of technological applications in various fields, such as composite materials1,2, chemical sensing3, biomedicine4,5,6, optoelectronics7,8,9 and nanoelectronics10,11,12. Colloidal nanocrystals are promising candidates in these fields, due to their ease of fabrication and processibility. Even more applications and new functional materials might emerge if nanocrystals could be synthesized in shapes of higher complexity than the ones produced by current methods (spheres, rods, discs)13,14,15,16,17,18,19. Here, we demonstrate that polytypism, or the existence of two or more crystal structures in different domains of the same crystal, coupled with the manipulation of surface energy at the nanoscale, can be exploited to produce branched inorganic nanostructures controllably. For the case of CdTe, we designed a high yield, reproducible synthesis of soluble, tetrapod-shaped nanocrystals through which we can independently control the width and length of the four arms.

1,407 citations


Journal ArticleDOI
TL;DR: In this article, the Langmuir−Blodgett technique was used to assemble monolayers (with areas over 20 cm2) of aligned silver nanowires that are ∼50 nm in diameter and 2−3 μm in length.
Abstract: Langmuir−Blodgett technique was used to assemble monolayers (with areas over 20 cm2) of aligned silver nanowires that are ∼50 nm in diameter and 2−3 μm in length. These nanowires possess pentagonal cross-sections and pyramidal tips. They are close-packed and are aligned parallel to each other. The resulting nanowire monolayers serve as excellent substrates for surface-enhanced Raman spectroscopy (SERS) with large electromagnetic field enhancement factors (2 × 105 for thiol and 2,4-dinitrotoluene, and 2 × 109 for Rhodamine 6G) and can readily be used in ultrasensitive, molecule-specific sensing utilizing vibrational signatures.

1,322 citations


Journal ArticleDOI
TL;DR: The results indicate that the senescence response to telomere dysfunction is reversible and is maintained primarily by p53, however, p16 provides a dominant second barrier to the unlimited growth of human cells.
Abstract: Telomere erosion and subsequent dysfunction limits the proliferation of normal human cells by a process termed replicative senescence. Replicative senescence is thought to suppress tumorigenesis by establishing an essentially irreversible growth arrest that requires activities of the p53 and pRB tumor suppressor proteins. We show that, depending on expression of the pRB regulator p16, replicative senescence is not necessarily irreversible. We used lentiviruses to express specific viral and cellular proteins in senescent human fibroblasts and mammary epithelial cells. Expression of telomerase did not reverse the senescence arrest. However, cells with low levels of p16 at senescence resumed robust growth upon p53 inactivation, and limited growth upon expression of oncogenic RAS. In contrast, cells with high levels of p16 at senescence failed to proliferate upon p53 inactivation or RAS expression, although they re-entered the cell cycle without growth after pRB inactivation. Our results indicate that the senescence response to telomere dysfunction is reversible and is maintained primarily by p53. However, p16 provides a dominant second barrier to the unlimited growth of human cells.

1,262 citations


Journal ArticleDOI
10 Apr 2003-Nature
TL;DR: An ‘epitaxial casting’ approach for the synthesis of single-crystal GaN nanotubes with inner diameters of 30–200 nm and wall thicknesses of 5–50‬nm is reported, applicable to many other semiconductor systems.
Abstract: Since the discovery of carbon nanotubes in 1991 (ref. 1), there have been significant research efforts to synthesize nanometre-scale tubular forms of various solids. The formation of tubular nanostructure generally requires a layered or anisotropic crystal structure. There are reports of nanotubes made from silica, alumina, silicon and metals that do not have a layered crystal structure; they are synthesized by using carbon nanotubes and porous membranes as templates, or by thin-film rolling. These nanotubes, however, are either amorphous, polycrystalline or exist only in ultrahigh vacuum. The growth of single-crystal semiconductor hollow nanotubes would be advantageous in potential nanoscale electronics, optoelectronics and biochemical-sensing applications. Here we report an 'epitaxial casting' approach for the synthesis of single-crystal GaN nanotubes with inner diameters of 30-200 nm and wall thicknesses of 5-50 nm. Hexagonal ZnO nanowires were used as templates for the epitaxial overgrowth of thin GaN layers in a chemical vapour deposition system. The ZnO nanowire templates were subsequently removed by thermal reduction and evaporation, resulting in ordered arrays of GaN nanotubes on the substrates. This templating process should be applicable to many other semiconductor systems.

1,169 citations


Journal ArticleDOI
TL;DR: Oxygen sensitivity is identified as a critical difference between mouse and human cells, explaining their proliferative differences in culture, and possibly their different rates of cancer and ageing.
Abstract: Most mammalian cells do not divide indefinitely, owing to a process termed replicative senescence. In human cells, replicative senescence is caused by telomere shortening, but murine cells senesce despite having long stable telomeres1. Here, we show that the phenotypes of senescent human fibroblasts and mouse embryonic fibroblasts (MEFs) differ under standard culture conditions, which include 20% oxygen. MEFs did not senesce in physiological (3%) oxygen levels, but underwent a spontaneous event that allowed indefinite proliferation in 20% oxygen. The proliferation and cytogenetic profiles of DNA repair-deficient MEFs suggested that DNA damage limits MEF proliferation in 20% oxygen. Indeed, MEFs accumulated more DNA damage in 20% oxygen than 3% oxygen, and more damage than human fibroblasts in 20% oxygen. Our results identify oxygen sensitivity as a critical difference between mouse and human cells, explaining their proliferative differences in culture, and possibly their different rates of cancer and ageing.

Journal ArticleDOI
TL;DR: The Sloan Digital Sky Survey (SDSS) has validated and made publicly available its First Data Release as discussed by the authors, which consists of 2099 deg2 of five-band (u, g, r, i, z) imaging data, 186,240 spectra of galaxies, quasars, stars and calibrating blank sky patches selected over 1360 deg 2 of this area.
Abstract: The Sloan Digital Sky Survey (SDSS) has validated and made publicly available its First Data Release. This consists of 2099 deg2 of five-band (u, g, r, i, z) imaging data, 186,240 spectra of galaxies, quasars, stars and calibrating blank sky patches selected over 1360 deg2 of this area, and tables of measured parameters from these data. The imaging data go to a depth of r ≈ 22.6 and are photometrically and astrometrically calibrated to 2% rms and 100 mas rms per coordinate, respectively. The spectra cover the range 3800–9200 A, with a resolution of 1800–2100. This paper describes the characteristics of the data with emphasis on improvements since the release of commissioning data (the SDSS Early Data Release) and serves as a pointer to extensive published and on-line documentation of the survey.

Journal ArticleDOI
TL;DR: In this paper, the authors show a clear correlation between the field effect mobility of RR P3HT and its molecular weight (MW) with mobility values increasing from 1.7 to 9.4 cm 2 V ± 1 s ± 1.5 kD.
Abstract: Semiconducting conjugated polymers are being developed for light-emitting diodes, [1,2] photovoltaic cells, [3,4] and thin-film transistors [5±7] because they can readily be deposited from solution onto almost any substrate. Clearly, it is important to maximize the charge carrier mobilities for all of these applications , especially for transistors and photovoltaic cells. Most conjugated polymers have hole mobilities in the range of 10 ±7 ±10 ±5 cm 2 V ±1 s ±1. The electron mobility is usually even lower because of traps with energies slightly below the lowest unoccupied molecular orbital (LUMO) level of the polymer. Poly(9,9¢-dioctylfluorene-co-2,2¢-bithiophene) (F8T2) has a higher hole mobility (as high as 10 ±2 cm 2 V ±1 s ±1) because of its liquid crystalline character. [8,9] Regioregular poly(3-hexyl-thiophene) (RR P3HT) has an even higher mobility (with quoted values as high as 10 ±1 cm 2 V ±1 s ±1) [10±12] because the regular arrangement of its side chains allows efficient p-stacking of the conjugated backbones. [11] Despite the achievements that have been made towards improving the mobility of conjugated polymers, much is still not known about how charge moves through the films and how the chain packing can be optimized to obtain even higher mobilities. Reported values for the mobilities in RR P3HT vary by orders of magnitude. [10±12] We now show a clear correlation between the field-effect mobility of RR P3HT and its molecular weight (MW) with mobility values increasing from 1.7 ” 10 ±6 to 9.4 ” 10 ±3 cm 2 V ±1 s ±1 as the MW is increased from 3.2 to 36.5 kD. These variations in MW are also accompanied by significant changes in film morphology. These observations probably explain why the mobility values obtained in different labs vary so widely and suggest that optimizing the MW of conjugated polymers could lead to significant improvements in device performance. Our studies were performed both on batches of RR P3HT that were synthesized in our laboratory by a modified McCul-lough route [13±15] and also with a commercial sample purchased from Aldrich, which was said to be prepared through the Rieke route. [16] MW control in our samples prepared by the modified McCullough route was achieved by adjusting the polymerization time. Since the commercial sample had a large polydispersity, we separated it into several low polydispersity fractions with different MWs through a series of Soxhlet extractions with solvents of increasing solvency (hexane, dichloromethane, and chloroform). …

Journal ArticleDOI
TL;DR: Reported ventilation and CO2 data strongly indicate that ventilation is inadequate in many classrooms, possibly leading to health symptoms, and should be a major focus of design or remediation efforts.
Abstract: We reviewed the literature on Indoor Air Quality (IAQ), ventilation, and building-related health problems in schools and identified commonly reported building-related health symptoms involving schools until 1999. We collected existing data on ventilation rates, carbon dioxide (CO2) concentrations and symptom-relevant indoor air contaminants, and evaluated information on causal relationships between pollutant exposures and health symptoms. Reported ventilation and CO2 data strongly indicate that ventilation is inadequate in many classrooms, possibly leading to health symptoms. Adequate ventilation should be a major focus of design or remediation efforts. Total volatile organic compounds, formaldehyde (HCHO) and microbiological contaminants are reported. Low HCHO concentrations were unlikely to cause acute irritant symptoms (<0.05 ppm), but possibly increased risks for allergen sensitivities, chronic irritation, and cancer. Reported microbiological contaminants included allergens in deposited dust, fungi, and bacteria. Levels of specific allergens were sufficient to cause symptoms in allergic occupants. Measurements of airborne bacteria and airborne and surface fungal spores were reported in schoolrooms. Asthma and 'sick building syndrome' symptoms are commonly reported. The few studies investigating causal relationships between health symptoms and exposures to specific pollutants suggest that such symptoms in schools are related to exposures to volatile organic compounds (VOCs), molds and microbial VOCs, and allergens.

Journal ArticleDOI
TL;DR: In this paper, a noniterative procedure is presented to calculate the composition of the compressed CO 2 and liquid H 2 O phases at equilibrium, based on equating chemical potentials and using the Redlich-Kwong equation of state to express departure from ideal behavior.

Journal ArticleDOI
21 Mar 2003-Cell
TL;DR: Crystal structures of c-Abl show that the N-terminal myristoyl modification of c -Abl 1b binds to the kinase domain and induces conformational changes that allow the SH2 and SH3 domains to dock onto it.

Book ChapterDOI
08 Jul 2003
TL;DR: In this article, a fully SAT-based method of unbounded symbolic model checking based on computing Craig interpolants was proposed, which is greatly more efficient than BDD-based symbolic model-checking.
Abstract: We consider a fully SAT-based method of unbounded symbolic model checking based on computing Craig interpolants. In benchmark studies using a set of large industrial circuit verification instances, this method is greatly more efficient than BDD-based symbolic model checking, and compares favorably to some recent SAT-based model checking methods on positive instances.

Journal ArticleDOI
TL;DR: Current knowledge regarding aberrations is summarized, their functional importance is discussed, their mechanisms by which aberration may form during cancer progression are suggested and examples of clinical advances that have come from studies of chromosome aberrings are provided.
Abstract: Chromosome aberrations in human solid tumors are hallmarks of gene deregulation and genome instability. This review summarizes current knowledge regarding aberrations, discusses their functional importance, suggests mechanisms by which aberrations may form during cancer progression and provides examples of clinical advances that have come from studies of chromosome aberrations.

Journal ArticleDOI
TL;DR: In this article, an inversion method was used to reconstruct the image of the object without the need for any such prior knowledge, without the knowledge of the shape of the objects and the low spatial frequencies unavoidably lost in experiments.
Abstract: A solution to the inversion problem of scattering would offer aberration-free diffraction-limited three-dimensional images without the resolution and depth-of-field limitations of lens-based tomographic systems. Powerful algorithms are increasingly being used to act as lenses to form such images. Current image reconstruction methods, however, require the knowledge of the shape of the object and the low spatial frequencies unavoidably lost in experiments. Diffractive imaging has thus previously been used to increase the resolution of images obtained by other means. Here we experimentally demonstrate an inversion method, which reconstructs the image of the object without the need for any such prior knowledge.

Journal Article
TL;DR: In benchmark studies using a set of large industrial circuit verification instances, this method is greatly more efficient than BDD-based symbolic model checking, and compares favorably to some recent SAT-based model checking methods on positive instances.
Abstract: We consider a fully SAT-based method of unbounded symbolic model checking based on computing Craig interpolants. In benchmark studies using a set of large industrial circuit verification instances, this method is greatly more efficient than BDD-based symbolic model checking, and compares favorably to some recent SAT-based model checking methods on positive instances.

Journal ArticleDOI
TL;DR: This review of recent biological applications of colloidal nanocrystals discusses the arrangement of nanocrystal–oligonucleotide conjugates using molecular scaffolds such as single-stranded DNA, and three different biological applications are introduced.
Abstract: Due to their interesting properties, research on colloidal nanocrystals has moved in the last few years from fundamental research to first applications in materials science and life sciences. In this review some recent biological applications of colloidal nanocrystals are discussed, without going into biological or chemical details. First, the properties of colloidal nanocrystals and how they can be synthesized are described. Second, the conjugation of nanocrystals with biological molecules is discussed. And third, three different biological applications are introduced: (i) the arrangement of nanocrystal–oligonucleotide conjugates using molecular scaffolds such as single-stranded DNA, (ii) the use of nanocrystal–protein conjugates as fluorescent probes for cellular imaging, and (iii) a motility assay based on the uptake of nanocrystals by living cells.

Journal ArticleDOI
TL;DR: A comprehensive review of methods to measure soil water content with ground penetrating radar (GPR) is presented in this article, where the authors distinguish four methods: reflected wave velocity, ground wave velocity and surface reflection coefficient.
Abstract: We present a comprehensive review of methods to measure soil water content with ground penetrating radar (GPR) We distinguish four methodologies: soil water content determined from reflected wave velocity, soil water content determined from ground wave velocity, soil water content determined from transmitted wave velocity between boreholes, and soil water content determined from the surface reflection coefficient For each of these four methodologies, we discuss the basic principles, illustrate the quality of the data with field examples, discuss the possibilities and limitations, and identify areas where future research is required We hope that this review will further stimulate the community to consider ground penetrating radar as one of the possible tools to measure soil water content

Journal ArticleDOI
TL;DR: In this paper, a microdevice consisting of two adjacent symmetric silicon nitride membranes suspended by long silicon-nitride beams for measuring thermophysical properties of one-dimensional manostructures (nanotubes, nanowires, and mmobelts) bridging the two membranes is fabricated.
Abstract: We have batch-fabricated a microdevice consisting of two adjacent symmetric silicon nitride membranes suspended by long silicon nitride beams for measuring thermophysical properties of one-dimensional manostructures (nanotubes, nanowires, and mmobelts) bridging the two membranes. A platinum resistance heater/thermometer is fabricated on each membrane. One membrane can be Joule heated to cause heat conduction through the sample to the other membrane. Thermal conductance, electrical conductance, and Seebeck coefficient can be measured using this microdevice in the temperature range of 4-400 K of an evacuated Helium cryostat. Measurement sensitivity, errors, and uncertainty are discussed. Measurement results of a 148 nm and a 10 nm-diameter single wall carbon nanotube bundle are presented.

Journal ArticleDOI
TL;DR: In this paper, an intercomparison study on undisturbed trade wind cumulus convection under steadystate conditions as observed during the Barbados Oceanographic and Meteorological Experiment (BOMEX) with 10 large eddy simulation (LES) models was performed.
Abstract: This paper reports an intercomparison study on undisturbed trade wind cumulus convection under steadystate conditions as observed during the Barbados Oceanographic and Meteorological Experiment (BOMEX) with 10 large eddy simulation (LES) models. A main objective of this study is to obtain a quantitative assessment of the quality of the turbulent dynamics for this type of boundary layer clouds as produced by the different LES codes. A 6-h simulation shows excellent model-to-model agreement of the observed vertical thermodynamical structure, reasonable agreement of variances and turbulent fluxes, and good agreement of quantities conditionally sampled within the model clouds, such as cloud cover, liquid water, and cloud updraft strength. In the second part of this paper the LES dataset is used to evaluate simple models that are used in parameterizations of current general circulation models (GCMs). Finally, the relation of this work to subsequent LES studies of more complicated regimes is discussed, and guidance is given for the design of future observational studies of shallow cumulus boundary layers.

Journal ArticleDOI
TL;DR: It was found that fracture in human cortical bone is consistent with strain-controlled failure, and the influence of microstructure can be described in terms of several toughening mechanisms, such as uncracked-ligament bridging.
Abstract: A mechanistic understanding of fracture in human bone is critical to predicting fracture risk associated with age and disease. Despite extensive work, a mechanistic framework for describing how the underlying microstructure affects the failure mode in bone is lacking.

Journal ArticleDOI
TL;DR: The main algorithmic features in the software package SuperLU_DIST, a distributed-memory sparse direct solver for large sets of linear equations, are presented, with an innovative static pivoting strategy proposed earlier by the authors.
Abstract: We present the main algorithmic features in the software package SuperLU_DIST, a distributed-memory sparse direct solver for large sets of linear equations. We give in detail our parallelization strategies, with a focus on scalability issues, and demonstrate the software's parallel performance and scalability on current machines. The solver is based on sparse Gaussian elimination, with an innovative static pivoting strategy proposed earlier by the authors. The main advantage of static pivoting over classical partial pivoting is that it permits a priori determination of data structures and communication patterns, which lets us exploit techniques used in parallel sparse Cholesky algorithms to better parallelize both LU decomposition and triangular solution on large-scale distributed machines.

Journal ArticleDOI
17 Oct 2003-Science
TL;DR: One category of functional sequences postulated to lie in gene deserts is gene regulatory sequences, which are related to transcriptional regulation and regulation of transcriptional reprograming.
Abstract: Approximately 25% of the genome consists of gene-poor regions greater than 500 kb, termed gene deserts ([ 1 ][1]). These segments have been minimally explored, and their functional significance remains elusive. One category of functional sequences postulated to lie in gene deserts is gene regulatory

Journal ArticleDOI
TL;DR: Two new soft X-ray scanning transmission microscopes located at the Advanced Light Source (ALS) have been designed, built and commissioned and interferometer control implemented in both microscopes allows the precise measurement of the transverse position of the zone plate relative to the sample.
Abstract: Two new soft X-ray scanning transmission microscopes located at the Advanced Light Source (ALS) have been designed, built and commissioned. Interferometer control implemented in both microscopes allows the precise measurement of the transverse position of the zone plate relative to the sample. Long-term positional stability and compensation for transverse displacement during translations of the zone plate have been achieved. The interferometer also provides low-distortion orthogonal x, y imaging. Two different control systems have been developed: a digital control system using standard VXI components at beamline 7.0, and a custom feedback system based on PC AT boards at beamline 5.3.2. Both microscopes are diffraction limited with the resolution set by the quality of the zone plates. Periodic features with 30 nm half period can be resolved with a zone plate that has a 40 nm outermost zone width. One microscope is operating at an undulator beamline (7.0), while the other is operating at a novel dedicated bending-magnet beamline (5.3.2), which is designed specifically to illuminate the microscope. The undulator beamline provides count rates of the order of tens of MHz at high-energy resolution with photon energies of up to about 1000 eV. Although the brightness of a bending-magnet source is about four orders of magnitude smaller than that of an undulator source, photon statistics limited operation with intensities in excess of 3 MHz has been achieved at high energy resolution and high spatial resolution. The design and performance of these microscopes are described.

Journal ArticleDOI
C. Adler1, Zubayer Ahammed2, C. E. Allgower3, J. Amonett4  +300 moreInstitutions (29)
TL;DR: The back-to-back correlations are reduced considerably in the most central Au+Au collisions, indicating substantial interaction as the hard-scattered partons or their fragmentation products traverse the medium.
Abstract: Azimuthal correlations for large transverse momentum charged hadrons have been measured over a wide pseudorapidity range and full azimuth in Au+Au and p+p collisions at roots(NN)=200 GeV. The small-angle correlations observed in p+p collisions and at all centralities of Au+Au collisions are characteristic of hard-scattering processes previously observed in high-energy collisions. A strong back-to-back correlation exists for p+p and peripheral Au+Au. In contrast, the back-to-back correlations are reduced considerably in the most central Au+Au collisions, indicating substantial interaction as the hard-scattered partons or their fragmentation products traverse the medium.

Journal ArticleDOI
Joseph Adams1, C. Adler2, Madan M. Aggarwal3, Zubayer Ahammed4  +364 moreInstitutions (39)
TL;DR: High statistics measurements of inclusive charged hadron production in Au+Au and p+p collisions at sqrt[s(NN)]=200 GeV report no evidence of p(T)-dependent suppression, which may be expected from models incorporating jet attenuation in cold nuclear matter or scattering of fragmentation hadrons.
Abstract: We report high statistics measurements of inclusive charged hadron production in Au+Au and p+p collisions at rootS(NN)=200 GeV. A large, approximately constant hadron suppression is observed in central Au+Au collisions for 5