Institution
Northwestern University
Education•Evanston, Illinois, United States•
About: Northwestern University is a education organization based out in Evanston, Illinois, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 75430 authors who have published 188857 publications receiving 9463252 citations. The organization is also known as: Northwestern & NU.
Topics: Population, Medicine, Cancer, Health care, Transplantation
Papers published on a yearly basis
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Harvard University1, National Institutes of Health2, Northwestern University3, Washington University in St. Louis4, Alzheimer's Association5, Mayo Clinic6, University of California, San Diego7, SUNY Downstate Medical Center8, University of Kentucky9, Rush University Medical Center10, University of Ulm11, University of Pennsylvania12, University of California, Los Angeles13, University of Washington14
TL;DR: The new guidelines recognize the pre‐clinical stage of AD, enhance the assessment of AD to include amyloid accumulation as well as neurofibrillary change and neuritic plaques, and establish protocols for the neuropathologic assessment of Lewy body disease, vascular brain injury, hippocampal sclerosis, and TDP‐43 inclusions.
Abstract: A consensus panel from the United States and Europe was convened recently to update and revise the 1997 consensus guidelines for the neuropathologic evaluation of Alzheimer's disease (AD) and other diseases of brain that are common in the elderly. The new guidelines recognize the pre-clinical stage of AD, enhance the assessment of AD to include amyloid accumulation as well as neurofibrillary change and neuritic plaques, establish protocols for the neuropathologic assessment of Lewy body disease, vascular brain injury, hippocampal sclerosis, and TDP-43 inclusions, and recommend standard approaches for the workup of cases and their clinico-pathologic correlation.
2,240 citations
French Institute of Health and Medical Research1, Institut Gustave Roussy2, University of Paris-Sud3, University of Texas Southwestern Medical Center4, Thomas Jefferson University5, University of Massachusetts Medical School6, Roswell Park Cancer Institute7, Johns Hopkins University School of Medicine8, Penn State Milton S. Hershey Medical Center9, Goethe University Frankfurt10, St. Jude Children's Research Hospital11, University of Zurich12, University College London13, South Australia Pathology14, University of Adelaide15, Ludwig Institute for Cancer Research16, University of Graz17, Istituto Superiore di Sanità18, University of Michigan19, Northwestern University20, University of Rome Tor Vergata21, University of Cambridge22, University of Bern23, Ghent University24, Harvard University25, Karolinska Institutet26, University of Leicester27
TL;DR: A functional classification of cell death subroutines is proposed that applies to both in vitro and in vivo settings and includes extrinsic apoptosis, caspase-dependent or -independent intrinsic programmed cell death, regulated necrosis, autophagic cell death and mitotic catastrophe.
Abstract: In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of recommendations for the definition of distinct cell death morphologies and for the appropriate use of cell death-related terminology, including 'apoptosis', 'necrosis' and 'mitotic catastrophe'. In view of the substantial progress in the biochemical and genetic exploration of cell death, time has come to switch from morphological to molecular definitions of cell death modalities. Here we propose a functional classification of cell death subroutines that applies to both in vitro and in vivo settings and includes extrinsic apoptosis, caspase-dependent or -independent intrinsic apoptosis, regulated necrosis, autophagic cell death and mitotic catastrophe. Moreover, we discuss the utility of expressions indicating additional cell death modalities. On the basis of the new, revised NCCD classification, cell death subroutines are defined by a series of precise, measurable biochemical features.
2,238 citations
TL;DR: It is shown that the optimum location of a switching center is always at a vertex of the communication network while the best location for the police station is not necessarily at an intersection.
Abstract: The concepts of the "center" and the "median vertex" of a graph are generalized to the "absolute center" and the "absolute median" of a weighted graph a graph with weights attached to its vertices as well as to its branches. These results are used to find the optimum location of a "switching center" in a communication network and to locate the best place to build a "police station" in a highway system. It is shown that the optimum location of a switching center is always at a vertex of the communication network while the best location for the police station is not necessarily at an intersection. Procedures for finding these locations are given.
2,224 citations
TL;DR: In this article, two tests for the number of common stochastic trends (i.e., for the order of cointegration) in a multiple time series with and without drift are developed.
Abstract: Cointegrated multiple time series share at least one common trend. Two tests are developed for the number of common stochastic trends (i.e., for the order of cointegration) in a multiple time series with and without drift. Both tests involve the roots of the ordinary least squares coefficient matrix obtained by regressing the series onto its first lag. Critical values for the tests are tabulated, and their power is examined in a Monte Carlo study. Economic time series are often modeled as having a unit root in their autoregressive representation, or (equivalently) as containing a stochastic trend. But both casual observation and economic theory suggest that many series might contain the same stochastic trends so that they are cointegrated. If each of n series is integrated of order 1 but can be jointly characterized by k > n stochastic trends, then the vector representation of these series has k unit roots and n — k distinct stationary linear combinations. Our proposed tests can be viewed alterna...
2,223 citations
TL;DR: Using the scalable technique of density-gradient ultracentrifugation, isolated narrow distributions of SWNTs in which >97% are within a 0.02-nm-diameter range are isolated.
Abstract: The heterogeneity of as-synthesized single-walled carbon nanotubes (SWNTs) precludes their widespread application in electronics, optics and sensing. We report on the sorting of carbon nanotubes by diameter, bandgap and electronic type using structure-discriminating surfactants to engineer subtle differences in their buoyant densities. Using the scalable technique of density-gradient ultracentrifugation, we have isolated narrow distributions of SWNTs in which >97% are within a 0.02-nm-diameter range. Furthermore, using competing mixtures of surfactants, we have produced bulk quantities of SWNTs of predominantly a single electronic type. These materials were used to fabricate thin-film electrical devices of networked SWNTs characterized by either metallic or semiconducting behaviour.
2,219 citations
Authors
Showing all 76189 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| George M. Whitesides | 240 | 1739 | 269833 |
| Ralph B. D'Agostino | 226 | 1287 | 229636 |
| Daniel Levy | 212 | 933 | 194778 |
| David Miller | 203 | 2573 | 204840 |
| Ronald M. Evans | 199 | 708 | 166722 |
| Michael Marmot | 193 | 1147 | 170338 |
| Robert C. Nichol | 187 | 851 | 162994 |
| Scott M. Grundy | 187 | 841 | 231821 |
| Stuart H. Orkin | 186 | 715 | 112182 |
| Michael A. Strauss | 185 | 1688 | 208506 |
| Ralph Weissleder | 184 | 1160 | 142508 |
| Patrick O. Brown | 183 | 755 | 200985 |
| Aaron R. Folsom | 181 | 1118 | 134044 |
| Valentin Fuster | 179 | 1462 | 185164 |
| Ronald C. Petersen | 178 | 1091 | 153067 |