Institution
Oklahoma State University–Stillwater
Education•Stillwater, Oklahoma, United States•
About: Oklahoma State University–Stillwater is a education organization based out in Stillwater, Oklahoma, United States. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 18267 authors who have published 36743 publications receiving 1107500 citations. The organization is also known as: Oklahoma State University & OKState.
Papers published on a yearly basis
Papers
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TL;DR: Results indicated that butyrate-induced synthesis of endogenous HDPs is a phylogenetically conserved mechanism of innate host defense shared by mammals and aves, and that dietary supplementation ofbutyrate has potential for further development as a convenient antibiotic-alternative strategy to enhance host innate immunity and disease resistance.
Abstract: Host defense peptides (HDPs) constitute a large group of natural broad-spectrum antimicrobials and an important first line of immunity in virtually all forms of life. Specific augmentation of synthesis of endogenous HDPs may represent a promising antibiotic-alternative approach to disease control. In this study, we tested the hypothesis that exogenous administration of butyrate, a major type of short-chain fatty acids derived from bacterial fermentation of undigested dietary fiber, is capable of inducing HDPs and enhancing disease resistance in chickens. We have found that butyrate is a potent inducer of several, but not all, chicken HDPs in HD11 macrophages as well as in primary monocytes, bone marrow cells, and jejuna and cecal explants. In addition, butyrate treatment enhanced the antibacterial activity of chicken monocytes against Salmonella enteritidis, with a minimum impact on inflammatory cytokine production, phagocytosis, and oxidative burst capacities of the cells. Furthermore, feed supplementation with 0.1% butyrate led to a significant increase in HDP gene expression in the intestinal tract of chickens. More importantly, such a feeding strategy resulted in a nearly 10-fold reduction in the bacterial titer in the cecum following experimental infections with S. enteritidis. Collectively, the results indicated that butyrate-induced synthesis of endogenous HDPs is a phylogenetically conserved mechanism of innate host defense shared by mammals and aves, and that dietary supplementation of butyrate has potential for further development as a convenient antibiotic-alternative strategy to enhance host innate immunity and disease resistance.
227 citations
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TL;DR: In this paper, the authors present a procedure for standard application of hydrologic/water quality models, which is an adaptation and extension of steps identified from relevant literature including guidance provided by the U.S. Environmental Protection Agency.
Abstract: This paper presents a procedure for standard application of hydrologic/water quality models. To date, most hydrologic/water quality modeling projects and studies have not utilized formal protocols, but rather have employed ad hoc approaches. The procedure proposed is an adaptation and extension of steps identified from relevant literature including guidance provided by the U.S. Environmental Protection Agency. This protocol provides guidance for establishing written plans prior to conducting modeling efforts. Eleven issues that should be addressed in model application plans were identified and discussed in the context of hydrologic/water quality studies. A graded approach for selection of the level of documentation for each item was suggested. The creation and use of environmental modeling plans is increasingly important as the results of modeling projects are used in decision-making processes that have significant implications. Standard modeling application protocols similar to the proposed procedure herein provide modelers with a roadmap to be followed, reduces modelers’ bias, enhances the reproducibility of model application studies, and eventually improves acceptance of modeling outcomes.
227 citations
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TL;DR: In this paper, a model is proposed to explain the luminescence properties of YVO4 crystals based on transitions within the VO3-4 ion, which predicts the observed temperature and concentration dependences for the fluorescence intensities and lifetimes.
227 citations
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TL;DR: This article analyzed the relationship between the outsourcing of human resource (HR) activities, namely training and payroll, and firm performance, and found that both outsourcing and payroll outsourcing have implications for firm performance.
227 citations
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TL;DR: In this article, an improved energy clustering algorithm is introduced, and its implications for the measurement and identification of prompt electrons and photons are discussed in detail, including corrections and calibrations that affect performance, including energy calibration, identification and isolation efficiencies.
Abstract: This paper describes the reconstruction of electrons and photons with the ATLAS detector, employed for measurements and searches exploiting the complete LHC Run 2 dataset. An improved energy clustering algorithm is introduced, and its implications for the measurement and identification of prompt electrons and photons are discussed in detail. Corrections and calibrations that affect performance, including energy calibration, identification and isolation efficiencies, and the measurement of the charge of reconstructed electron candidates are determined using up to 81 fb−1 of proton-proton collision data collected at √s=13 TeV between 2015 and 2017.
227 citations
Authors
Showing all 18403 results
Name | H-index | Papers | Citations |
---|---|---|---|
Gerald I. Shulman | 164 | 579 | 109520 |
James M. Tiedje | 150 | 688 | 102287 |
Robert J. Sternberg | 149 | 1066 | 89193 |
Josh Moss | 139 | 1019 | 89255 |
Brad Abbott | 137 | 1566 | 98604 |
Itsuo Nakano | 135 | 1539 | 97905 |
Luis M. Liz-Marzán | 132 | 616 | 61684 |
Flera Rizatdinova | 130 | 1242 | 89525 |
Bernd Stelzer | 129 | 1209 | 81931 |
Alexander Khanov | 129 | 1219 | 87089 |
Dugan O'Neil | 128 | 1000 | 80700 |
Michel Vetterli | 128 | 901 | 76064 |
Josu Cantero | 126 | 846 | 73616 |
Nicholas A. Kotov | 123 | 574 | 55210 |
Wei Chen | 122 | 1946 | 89460 |