Rio de Janeiro State University

About: Rio de Janeiro State University is a education organization based out in Rio de Janeiro, Brazil. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 16631 authors who have published 30919 publications receiving 465753 citations. The organization is also known as: UERJ & Rio de Janeiro State University.

2015 Recommendations for the Management of Polymyalgia Rheumatica: A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative

Abstract: Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.

A framework for remission in SLE: consensus findings from a large international task force on definitions of remission in SLE (DORIS)

Abstract: Objectives Treat-to-target recommendations have identified ‘remission’ as a target in systemic lupus erythematosus (SLE), but recognise that there is no universally accepted definition for this. Therefore, we initiated a process to achieve consensus on potential definitions for remission in SLE. Methods An international task force of 60 specialists and patient representatives participated in preparatory exercises, a face-to-face meeting and follow-up electronic voting. The level for agreement was set at 90%. Results The task force agreed on eight key statements regarding remission in SLE and three principles to guide the further development of remission definitions: 1. Definitions of remission will be worded as follows: remission in SLE is a durable state characterised by …………………. (reference to symptoms, signs, routine labs). 2. For defining remission, a validated index must be used, for example, clinical systemic lupus erythematosus disease activity index (SLEDAI)=0, British Isles lupus assessment group (BILAG) 2004 D/E only, clinical European consensus lupus outcome measure (ECLAM)=0; with routine laboratory assessments included, and supplemented with physician9s global assessment. 3. Distinction is made between remission off and on therapy: remission off therapy requires the patient to be on no other treatment for SLE than maintenance antimalarials; and remission on therapy allows patients to be on stable maintenance antimalarials, low-dose corticosteroids (prednisone ≤5 mg/day), maintenance immunosuppressives and/or maintenance biologics. The task force also agreed that the most appropriate outcomes (dependent variables) for testing the prognostic value (construct validity) of potential remission definitions are: death, damage, flares and measures of health-related quality of life. Conclusions The work of this international task force provides a framework for testing different definitions of remission against long-term outcomes.

Alimentos mais consumidos no Brasil: Inquérito Nacional de Alimentação 2008-2009

Abstract: OBJETIVO: Caracterizar o consumo alimentar mais frequente da populacao brasileira. METODOS: Foram analisados dados referentes ao primeiro dia de registro alimentar de 34.003 individuos com dez anos ou mais de idade que responderam ao Inquerito Nacional de Alimentacao, composto por amostra probabilistica da Pesquisa de Orcamentos Familiares 2008-2009. O padrao de consumo foi analisado segundo sexo, grupo etario, regiao e faixa de renda familiar per capita. RESULTADOS: Os alimentos mais frequentemente referidos pela populacao brasileira foram arroz (84,0%), cafe (79,0%), feijao (72,8%), pao de sal (63,0%) e carne bovina (48,7%), destacando-se tambem o consumo de sucos e refrescos (39,8%), refrigerantes (23,0%) e menor presenca de frutas (16,0%) e hortalicas (16,0%). Essa configuracao apresenta pouca variacao quando se consideram os estratos de sexo e faixa etaria; contudo, observa-se que os adolescentes foram o unico grupo etario que deixou de citar qualquer hortalica e que incluiu doces, bebida lactea e biscoitos doces entre os itens mais consumidos. Alimentos marcadamente de consumo regional incluem a farinha de mandioca no Norte e Nordeste e o cha na regiao Sul. Houve discrepâncias no consumo alimentar entre os estratos de menor e maior renda: individuos no quarto de renda mais elevada referiram sanduiches, tomate e alface e aqueles no primeiro quarto de renda citaram os peixes e preparacoes a base de peixe e farinha de mandioca entre os alimentos mais referidos. CONCLUSOES: Existe um padrao basico do consumo alimentar no Brasil que inclui entre os alimentos mais consumidos arroz, cafe, feijao, pao de sal e carne bovina, associado ao consumo regional de alguns poucos itens. Particularmente entre os adolescentes, alimentos ricos em gordura e acucar sao tambem de consumo frequente.

Upsilon production cross section in pp collisions at √s=7 TeV

Abstract: The Upsilon production cross section in proton-proton collisions at sqrt(s) = 7 TeV is measured using a data sample collected with the CMS detector at the LHC, corresponding to an integrated luminosity of 3.1 +/- 0.3 inverse picobarns. Integrated over the rapidity range |y|<2, we find the product of the Upsilon(1S) production cross section and branching fraction to dimuons to be sigma(pp to Upsilon(1S) X) B(Upsilon(1S) to mu+ mu-) = 7.37 +/- 0.13^{+0.61}_{-0.42}\pm 0.81 nb, where the first uncertainty is statistical, the second is systematic, and the third is associated with the estimation of the integrated luminosity of the data sample. This cross section is obtained assuming unpolarized Upsilon(1S) production. If the Upsilon(1S) production polarization is fully transverse or fully longitudinal the cross section changes by about 20%. We also report the measurement of the Upsilon(1S), Upsilon(2S), and Upsilon(3S) differential cross sections as a function of transverse momentum and rapidity.

Evidence for Collective Multiparticle Correlations in p-Pb Collisions

Abstract: The second-order azimuthal anisotropy Fourier harmonics, v2, are obtained in pPb and PbPb collisions over a wide pseudorapidity (eta) range based on correlations among six or more charged particles. The pPb data, corresponding to an integrated luminosity of 35 inverse nanobarns, were collected during the 2013 LHC pPb run at a nucleon-nucleon center-of-mass energy of 5.02 TeV by the CMS experiment. A sample of semi-peripheral PbPb collision data at sqrt(s[NN])= 2.76 TeV, corresponding to an integrated luminosity of 2.5 inverse microbarns and covering a similar range of particle multiplicities as the pPb data, is also analyzed for comparison. The six- and eight-particle cumulant and the Lee-Yang zeros methods are used to extract the v2 coefficients, extending previous studies of two- and four-particle correlations. For both the pPb and PbPb systems, the v2 values obtained with correlations among more than four particles are consistent with previously published four-particle results. These data support the interpretation of a collective origin for the previously observed long-range (large Delta[eta]) correlations in both systems. The ratios of v2 values corresponding to correlations including different numbers of particles are compared to theoretical predictions that assume a hydrodynamic behavior of a pPb system dominated by fluctuations in the positions of participant nucleons. These results provide new insights into the multi-particle dynamics of collision systems with a very small overlapping region.