Sungkyunkwan University

About: Sungkyunkwan University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Thin film & Graphene. The organization has 28229 authors who have published 56428 publications receiving 1352733 citations. The organization is also known as: 성균관대학교.

Autologous Mesenchymal Stem Cell Therapy Delays the Progression of Neurological Deficits in Patients With Multiple System Atrophy

Abstract: We evaluated the feasibility and safety of therapy with mesenchymal stem cells (MSCs) through consecutively intra-arterial and three repeated intravenous injections and compared the long-term prognosis between MSC-treated (n=11) and control multiple system atrophy (MSA) patients (n=18). The MSC-treated patients showed significantly greater improvement on the unified MSA rating scale (UMSARS) than the control patients at all visits throughout the 12-month study period. Orthostasis in UMSARS I items and cerebellar dysfunction-related items of UMSARS II items were significantly different in favor of MSC treatment compared to controls. Serial positron emission tomography scan in the MSC-treated group showed that increased fluorodeoxyglucose uptake from baseline was noted in cerebellum and frontal white matters. No serious adverse effects related to MSC therapy occurred. This study demonstrated that MSC therapy in patients with MSA was safe and delayed the progression of neurological deficits with achievement of functional improvement in the follow-up period. Clinical Pharmacology & Therapeutics (2008); 83, 5, 723–730. doi:10.1038/sj.clpt.6100386

Existence of solutions for nonlinear fractional stochastic differential equations

Abstract: The fractional stochastic differential equations have wide applications in various fields of science and engineering. This paper addresses the issue of existence of mild solutions for a class of fractional stochastic differential equations with impulses in Hilbert spaces. Using fractional calculations, fixed point technique, stochastic analysis theory and methods adopted directly from deterministic fractional equations, new set of sufficient conditions are formulated and proved for the existence of mild solutions for the fractional impulsive stochastic differential equation with infinite delay. Further, we study the existence of solutions for fractional stochastic semilinear differential equations with nonlocal conditions. Examples are provided to illustrate the obtained theory.

Genome of the red alga Porphyridium purpureum

Abstract: The limited knowledge we have about red algal genomes comes from the highly specialized extremophiles, Cyanidiophyceae. Here, we describe the first genome sequence from a mesophilic, unicellular red alga, Porphyridium purpureum. The 8,355 predicted genes in P. purpureum, hundreds of which are likely to be implicated in a history of horizontal gene transfer, reside in a genome of 19.7 Mbp with 235 spliceosomal introns. Analysis of light-harvesting complex proteins reveals a nuclear-encoded phycobiliprotein in the alga. We uncover a complex set of carbohydrate-active enzymes, identify the genes required for the methylerythritol phosphate pathway of isoprenoid biosynthesis, and find evidence of sexual reproduction. Analysis of the compact, function-rich genome of P. purpureum suggests that ancestral lineages of red algae acted as mediators of horizontal gene transfer between prokaryotes and photosynthetic eukaryotes, thereby significantly enriching genomes across the tree of photosynthetic life.

High Pseudocapacitance from Ultrathin V2O5 Films Electrodeposited on Self‐Standing Carbon‐Nanofiber Paper

Abstract: An ultrathin V2O5 layer was electrodeposited by cyclic voltammetry on a self-standing carbon-nanofiber paper, which was obtained by stabilization and heat-treatment of an electrospun polyacrylonitrile (PAN)-based nanofiber paper. A very-high capacitance of 1308 F g−1 was obtained in a 2 M KCl electrolyte when the contribution from the 3 nm thick vanadium oxide was considered alone, contributing to over 90% of the total capacitance (214 F g−1) despite the low weight percentage of the V2O5 (15 wt%). The high capacitance of the V2O5 is attributed to the large external surface area of the carbon nanofibers and the maximum number of active sites for the redox reaction of the ultrathin V2O5 layer. This ultrathin layer is almost completely accessible to the electrolyte and thus results in maximum utilization of the oxide (i.e., minimization of dead volume). This hypothesis was experimentally evaluated by testing V2O5 layers of different thicknesses.