Institution
Sungkyunkwan University
Education•Seoul, South Korea•
About: Sungkyunkwan University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Thin film & Graphene. The organization has 28229 authors who have published 56428 publications receiving 1352733 citations. The organization is also known as: 성균관대학교.
Topics: Thin film, Graphene, Population, Catalysis, Layer (electronics)
Papers published on a yearly basis
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TL;DR: In this article, the physics potential of a long baseline neutrino experiment using the Hyper-Kamiokande detector and neutrinos from the J-PARC proton synchrotron is presented.
Abstract: Hyper-Kamiokande will be a next generation underground water Cherenkov detector with a total (fiducial) mass of 0.99 (0.56) million metric tons, approximately 20 (25) times larger than that of Super-Kamiokande. One of the main goals of Hyper-Kamiokande is the study of $CP$ asymmetry in the lepton sector using accelerator neutrino and anti-neutrino beams. In this paper, the physics potential of a long baseline neutrino experiment using the Hyper-Kamiokande detector and a neutrino beam from the J-PARC proton synchrotron is presented. The analysis uses the framework and systematic uncertainties derived from the ongoing T2K experiment. With a total exposure of 7.5 MW $\times$ 10$^7$ sec integrated proton beam power (corresponding to $1.56\times10^{22}$ protons on target with a 30 GeV proton beam) to a $2.5$-degree off-axis neutrino beam, it is expected that the leptonic $CP$ phase $\delta_{CP}$ can be determined to better than 19 degrees for all possible values of $\delta_{CP}$, and $CP$ violation can be established with a statistical significance of more than $3\,\sigma$ ($5\,\sigma$) for $76\%$ ($58\%$) of the $\delta_{CP}$ parameter space. Using both $
u_e$ appearance and $
u_\mu$ disappearance data, the expected 1$\sigma$ uncertainty of $\sin^2\theta_{23}$ is 0.015(0.006) for $\sin^2\theta_{23}=0.5(0.45)$.
310 citations
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TL;DR: A transdermal preparation containing ketoprofen was developed using O/W microemulsion system and only limonene resulted in a powerful enhancing activity (3-fold increase over control) when evaluated with excised rat skins.
310 citations
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TL;DR: EGFR TKI-resistant SCLCs are branched out early from the LADC clones that harbor completely inactivated RB1 and TP53, and they share a common clonal origin and undergoBranched evolutionary trajectories.
Abstract: Purpose Histologic transformation of EGFR mutant lung adenocarcinoma (LADC) into small-cell lung cancer (SCLC) has been described as one of the major resistant mechanisms for epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). However, the molecular pathogenesis is still unclear. Methods We investigated 21 patients with advanced EGFR-mutant LADCs that were transformed into EGFR TKI-resistant SCLCs. Among them, whole genome sequencing was applied for nine tumors acquired at various time points from four patients to reconstruct their clonal evolutionary history and to detect genetic predictors for small-cell transformation. The findings were validated by immunohistochemistry in 210 lung cancer tissues. Results We identified that EGFR TKI-resistant LADCs and SCLCs share a common clonal origin and undergo branched evolutionary trajectories. The clonal divergence of SCLC ancestors from the LADC cells occurred before the first EGFR TKI treatments, and the complete inactivation of both RB1 and TP53 were observed from the early LADC stages in sequenced tumors. We extended the findings by immunohistochemistry in the early-stage LADC tissues of 75 patients treated with EGFR TKIs; inactivation of both Rb and p53 was strikingly more frequent in the small-cell-transformed group than in the nontransformed group (82% v 3%; odds ratio, 131; 95% CI, 19.9 to 859). Among patients registered in a predefined cohort (n = 65), an EGFR mutant LADC that harbored completely inactivated Rb and p53 had a 43× greater risk of small-cell transformation (relative risk, 42.8; 95% CI, 5.88 to 311). Branch-specific mutational signature analysis revealed that apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC)-induced hypermutation was frequent in the branches toward small-cell transformation. Conclusion EGFR TKI-resistant SCLCs are branched out early from the LADC clones that harbor completely inactivated RB1 and TP53. The evaluation of RB1 and TP53 status in EGFR TKI-treated LADCs is informative in predicting small-cell transformation.
309 citations
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TL;DR: Understanding chemical species in precursor solution, crystal growth kinetics, light-matter interaction, and controlling defects is expected to give important insights into not only reproducible production of high PCE over 20% but also further enhancement of the PCE of PCSs.
Abstract: A perovskite solar cell (PSC) employing an organic-inorganic lead halide perovskite light harvester, seeded in 2009 with power conversion efficiency (PCE) of 3.8% and grown in 2011 with PCE of 6.5% in dye-sensitized solar cell structure, has received great attention since the breakthrough reports ≈10% efficient solid-state PCSs demonstrating 500 h stability. Developments of device layout and high-quality perovskite film eventually lead to a PCE over 22%. As of October 31, 2017, the highest PCE of 22.7% is listed in an efficiency chart provided by NREL. In this Review, the methodologies to obtain highly efficient PSCs are described in detail. In order to achieve a PCE of over 20% reproducibly, key technologies are disclosed from the viewpoint of precursor solution chemistry, processing for defect-free perovskite films, and passivation of grain boundaries. Understanding chemical species in precursor solution, crystal growth kinetics, light-matter interaction, and controlling defects is expected to give important insights into not only reproducible production of high PCE over 20% but also further enhancement of the PCE of PCSs.
308 citations
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University of Tokyo1, Budker Institute of Nuclear Physics2, École Polytechnique Fédérale de Lausanne3, University of Sydney4, University of Melbourne5, Panjab University, Chandigarh6, National United University7, Polish Academy of Sciences8, University of Maribor9, National Taiwan University10, National Central University11, Hanyang University12, Yonsei University13, Gyeongsang National University14, Sungkyunkwan University15, Virginia Tech16, University of Cincinnati17, Tata Institute of Fundamental Research18, Korea University19, Nagoya University20, Nara Women's University21, Osaka University22, Tohoku Gakuin University23, Kyungpook National University24, Saga University25, Tokyo Institute of Technology26, Chiba University27, Niigata University28, Seoul National University29, Graduate University for Advanced Studies30, University of Ljubljana31, University of Giessen32, Austrian Academy of Sciences33, Osaka City University34, Tokyo University of Agriculture and Technology35, Toho University36, Kanagawa University37, University of Nova Gorica38, Tokyo Metropolitan University39, Tohoku University40, University of Science and Technology of China41
TL;DR: In this paper, the authors presented a method to solve the problem of the EKF problem in PhysRevLett, a Web of Science Record created on 2010-11-05, modified on 2017-12-10.
Abstract: Reference EPFL-ARTICLE-154576doi:10.1103/PhysRevLett.99.142002View record in Web of Science Record created on 2010-11-05, modified on 2017-12-10
308 citations
Authors
Showing all 28506 results
Name | H-index | Papers | Citations |
---|---|---|---|
Michael Grätzel | 248 | 1423 | 303599 |
Hyun-Chul Kim | 176 | 4076 | 183227 |
Yongsun Kim | 156 | 2588 | 145619 |
David J. Mooney | 156 | 695 | 94172 |
Jongmin Lee | 150 | 2257 | 134772 |
Byung-Sik Hong | 146 | 1557 | 105696 |
Inkyu Park | 144 | 1767 | 109433 |
Y. Choi | 141 | 1631 | 98709 |
Kazunori Kataoka | 138 | 908 | 70412 |
E. J. Corey | 136 | 1377 | 84110 |
Pasi A. Jänne | 136 | 685 | 89488 |
Suyong Choi | 135 | 1495 | 97053 |
Intae Yu | 134 | 1372 | 89870 |
Tae Jeong Kim | 132 | 1420 | 93959 |
Anders Hagfeldt | 129 | 600 | 79912 |