Institution
The Chinese University of Hong Kong
Education•Hong Kong, China•
About: The Chinese University of Hong Kong is a education organization based out in Hong Kong, China. It is known for research contribution in the topics: Population & Computer science. The organization has 43411 authors who have published 93672 publications receiving 3066651 citations.
Topics: Population, Computer science, Cancer, Medicine, China
Papers published on a yearly basis
Papers
More filters
••
TL;DR: Tissue synchronization imaging allows quick evaluation of regional wall delay, and combined with Ts-SD-12-ejection provides a reliable way of predicting reverse remodeling after CRT.
393 citations
••
TL;DR: In this article, the authors identify an important channel through which excess control rights affect firm value and find that the cost of debt financing is significantly higher for companies with a wider divergence between the largest ultimate owner's control rights and cash-flow rights.
393 citations
••
TL;DR: The exercise capacity and health status of SARS survivors was considerably lower than that of a normal population at 6 months and the functional disability appears out of proportion to the degree of lung function impairment and may be related to additional factors such as muscle deconditioning and steroid myopathy.
Abstract: Objective: To examine the impact of severe acute respiratory syndrome (SARS) on pulmonary function, exercise capacity, and health-related quality of life (HRQoL) among survivors.
Methods: 110 survivors with confirmed SARS were evaluated at the Prince of Wales Hospital, HK at the end of 3 and 6 months after symptom onset. The assessment included lung volumes (TLC, VC, RV, FRC), spirometry (FVC, FEV1), carbon monoxide transfer factor (TLCO adjusted for haemoglobin), inspiratory and expiratory respiratory muscle strength (Pimax and Pemax), 6 minute walk distance (6MWD), chest radiographs, and HRQoL by SF-36 questionnaire.
Results: There were 44 men and 66 women with a mean (SD) age of 35.6 (9.8) years and body mass index of 23.1 (4.8) kg/m2. Seventy (64%) were healthcare workers. At 6 months 33 subjects (30%) had abnormal chest radiographs; four (3.6%), eight (7.4%), and 17 (15.5%) patients had FVC, TLC, and TLCO below 80% of predicted values; and 15 (13.9%) and 24 (22.2%) had Pimax and Pemax values below 80 cm H2O, respectively. The 6MWD increased from a mean (SD) of 464 (83) m at 3 months to 502 (95) m (95% CI 22 to 54 m, p<0.001), but the results were lower than normal controls in the same age groups. There was impairment of HRQoL at 6 months. Patients who required ICU admission (n = 31) had significantly lower FVC, TLC, and TLCO than those who did not.
Conclusion: The exercise capacity and health status of SARS survivors was considerably lower than that of a normal population at 6 months. Significant impairment in surface area for gas exchange was noted in 15.5% of survivors. The functional disability appears out of proportion to the degree of lung function impairment and may be related to additional factors such as muscle deconditioning and steroid myopathy.
393 citations
••
TL;DR: A primary gastric cancer organoid biobank that comprises normal, dysplastic, cancer, and lymph node metastases from 34 patients, including detailed whole-exome and transcriptome analysis, provides a useful resource for studying both cancer cell biology and precision cancer therapy.
393 citations
••
TL;DR: In this article, the authors investigated the interaction effects of perceived environmental uncertainty (PEU), decentralization and management accounting systems (MAS) design on managerial performance and found that MAS design was defined in terms of perceived availability of two characteristics of information, which were scope and level of aggregation.
Abstract: This study investigated the interaction effects of perceived environmental uncertainty (PEU), decentralization and management accounting systems (MAS) design on managerial performance. MAS design was defined in terms of perceived availability of two characteristics of information, which were scope and level of aggregation. The responses of 48 managers, drawn from a cross-section of Singapore companies, to a questionnaire survey were analysed by examining the regression equations for the three-way interaction model and the partial derivatives of the equations. The results indicated that decentralization and the availability of MAS information characteristics of broad scope and aggregation were associated with higher managerial performance under conditions of high PEU. Under conditions of low PEU, decentralization and the availability of MAS broad scope and aggregated information were associated with lower managerial performance.
393 citations
Authors
Showing all 43993 results
Name | H-index | Papers | Citations |
---|---|---|---|
Michael Marmot | 193 | 1147 | 170338 |
Jing Wang | 184 | 4046 | 202769 |
Jiaguo Yu | 178 | 730 | 113300 |
Yang Yang | 171 | 2644 | 153049 |
Mark Gerstein | 168 | 751 | 149578 |
Gang Chen | 167 | 3372 | 149819 |
Jun Wang | 166 | 1093 | 141621 |
Jean Louis Vincent | 161 | 1667 | 163721 |
Wei Zheng | 151 | 1929 | 120209 |
Rui Zhang | 151 | 2625 | 107917 |
Ben Zhong Tang | 149 | 2007 | 116294 |
Kypros H. Nicolaides | 147 | 1302 | 87091 |
Thomas S. Huang | 146 | 1299 | 101564 |
Galen D. Stucky | 144 | 958 | 101796 |
Joseph J.Y. Sung | 142 | 1240 | 92035 |