Institution
University of Jena
Education•Jena, Thüringen, Germany•
About: University of Jena is a education organization based out in Jena, Thüringen, Germany. It is known for research contribution in the topics: Laser & Population. The organization has 22198 authors who have published 45159 publications receiving 1401514 citations. The organization is also known as: Friedrich-Schiller-Universität Jena & Friedrich Schiller University Jena.
Topics: Laser, Population, Fiber laser, Femtosecond, Raman spectroscopy
Papers published on a yearly basis
Papers
More filters
University of Jena1, University of Bologna2, Cornell University3, Wayne State University4, Imperial College London5, University of Liverpool6, Georgia Regents University7, Huntsman Cancer Institute8, Norwegian University of Science and Technology9, University of South Australia10, University of Amsterdam11, University of Texas MD Anderson Cancer Center12, Catholic University of Korea13, University of Chicago14, University of Toronto15, University of Bordeaux16, Masaryk University17, Leipzig University18, University of Naples Federico II19, Fred Hutchinson Cancer Research Center20, Lund University21, University of Turin22, Heidelberg University23, Russian Academy24
TL;DR: An expert panel to critically evaluate and update the evidence to achieve goals to achieve a stable deep molecular response (DMR) and discontinuing medication for treatment-free remission (TFR) in chronic myeloid leukemia.
Abstract: The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over the past 7 years. Most patients with chronic phase (CP) now have a normal life expectancy. Another goal is achieving a stable deep molecular response (DMR) and discontinuing medication for treatment-free remission (TFR). The European LeukemiaNet convened an expert panel to critically evaluate and update the evidence to achieve these goals since its previous recommendations. First-line treatment is a tyrosine kinase inhibitor (TKI; imatinib brand or generic, dasatinib, nilotinib, and bosutinib are available first-line). Generic imatinib is the cost-effective initial treatment in CP. Various contraindications and side-effects of all TKIs should be considered. Patient risk status at diagnosis should be assessed with the new EUTOS long-term survival (ELTS)-score. Monitoring of response should be done by quantitative polymerase chain reaction whenever possible. A change of treatment is recommended when intolerance cannot be ameliorated or when molecular milestones are not reached. Greater than 10% BCR-ABL1 at 3 months indicates treatment failure when confirmed. Allogeneic transplantation continues to be a therapeutic option particularly for advanced phase CML. TKI treatment should be withheld during pregnancy. Treatment discontinuation may be considered in patients with durable DMR with the goal of achieving TFR.
683 citations
TL;DR: In this paper, the basic strategies towards charged and non-charged iridium(III) complexes are summarized, and a wide range of assemblies are discussed, with special emphasis on the latter with respect to synthesis, characterization, electro-optical properties, processing technologies, and performance.
Abstract: The recent developments in using iridium(III) complexes as phosphorescent emitters in electroluminescent devices, such as (white) organic light-emitting diodes and light-emitting electrochemical cells, are discussed. Additionally, applications in the emerging fields of molecular sensors, biolabeling, and photocatalysis are briefly evaluated. The basic strategies towards charged and non-charged iridium(III) complexes are summarized, and a wide range of assemblies is discussed. Small-molecule- and polymer-based materials are under intense investigation as emissive systems in electroluminescent devices, and special emphasis is placed on the latter with respect to synthesis, characterization, electro-optical properties, processing technologies, and performance.
682 citations
University of Glasgow1, University of Salerno2, Max Planck Society3, University of Southampton4, University of Paris-Sud5, University of Nice Sophia Antipolis6, Washington State University7, Istituto Nazionale di Fisica Nucleare8, University of Warsaw9, University of Naples Federico II10, University of Birmingham11, Cardiff University12, University of Rome Tor Vergata13, Moscow State University14, California Institute of Technology15, VU University Amsterdam16, fondazione bruno kessler17, Leibniz University of Hanover18, University of Cambridge19, University of Tübingen20, University of Urbino21, University of Jena22, University of the Balearic Islands23, Northwestern University24, University of Minnesota25, University of Savoy26, Pennsylvania State University27, University of Pisa28, Roma Tre University29, Sapienza University of Rome30, University of Mississippi31
TL;DR: In this article, a special focus is set on evaluating the frequency band below 10 Hz where a complex mixture of seismic, gravity gradient, suspension thermal and radiation pressure noise dominates, including the most relevant fundamental noise contributions.
Abstract: Advanced gravitational wave detectors, currently under construction, are expected to directly observe gravitational wave signals of astrophysical origin. The Einstein Telescope (ET), a third-generation gravitational wave detector, has been proposed in order to fully open up the emerging field of gravitational wave astronomy. In this paper we describe sensitivity models for ET and investigate potential limits imposed by fundamental noise sources. A special focus is set on evaluating the frequency band below 10 Hz where a complex mixture of seismic, gravity gradient, suspension thermal and radiation pressure noise dominates. We develop the most accurate sensitivity model, referred to as ET-D, for a third-generation detector so far, including the most relevant fundamental noise contributions.
682 citations
TL;DR: It is indicated that ROS are essential signaling molecules which are required to promote health and longevity and the concept of mitohormesis provides a common mechanistic denominator for the physiological effects of physical exercise, reduced calorie uptake, glucose restriction, and possibly beyond.
681 citations
TL;DR: Micro computer tomography analysis demonstrated the capability to fabricate three-dimensional structures with an interconnected porosity and pore sizes suitable for tissue ingrowth and vascularization and a chemical surface modification is expected to enhance the fixation of the implant in the surrounding bone as well as to improve its long-term stability.
676 citations
Authors
Showing all 22435 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Cornelia M. van Duijn | 183 | 1030 | 146009 |
| Veikko Salomaa | 162 | 843 | 135046 |
| Andreas Pfeiffer | 149 | 1756 | 131080 |
| Bernhard O. Palsson | 147 | 831 | 85051 |
| Robert Huber | 139 | 671 | 73557 |
| Joachim Heinrich | 136 | 1309 | 76887 |
| Michael Schmitt | 134 | 2007 | 114667 |
| Paul D.P. Pharoah | 130 | 794 | 71338 |
| David Robertson | 127 | 1106 | 67914 |
| Yuri S. Kivshar | 126 | 1845 | 79415 |
| Ulrich S. Schubert | 122 | 2229 | 85604 |
| Andreas Hochhaus | 117 | 923 | 68685 |
| Werner Seeger | 114 | 1113 | 57464 |
| Th. Henning | 110 | 1036 | 44699 |
| Sascha Husa | 107 | 362 | 69907 |