Institution
University of Madras
Education•Chennai, Tamil Nadu, India•
About: University of Madras is a education organization based out in Chennai, Tamil Nadu, India. It is known for research contribution in the topics: Ring (chemistry) & Lipid peroxidation. The organization has 8496 authors who have published 11369 publications receiving 211152 citations. The organization is also known as: Madras University & University of Chennai.
Papers published on a yearly basis
Papers
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TL;DR: Findings indicate the synergistic protective effect of ferulic acid and ascorbic acid on lipid peroxidation and antioxidant defense system during ISO-induced myocardial infarction and associated oxidative stress in rats.
Abstract: Studies on the lipid peroxidation and antioxidant changes and their significance during myocardial injury have provided a new insight into the pathogenesis of heart disease. The heart failure subsequent to myocardial infarction may be associated with an antioxidant deficit as well as increased myocardial oxidative stress. The present study was designed to evaluate the effect of the combination of ferulic acid and ascorbic acid on antioxidant defense system and lipid peroxidation against isoproterenol (ISO)-induced myocardial infarction in rats. Induction of rats with isoproterenol (150 mg/kg body weight daily, i.p.) for 2 days resulted in a marked elevation in lipid peroxidation, serum marker enzymes (LDH, CPK, GOT, and GPT), and a significant decrease in activities of endogenous antioxidants (SOD, GPx, GST, CAT, and GSH). Pre-co-treatment with the combination of ferulic acid (20 mg/kg body weight/day) and ascorbic acid (80 mg/kg body weight/day) orally for 6 days, significantly attenuated these changes when compared to the individual treatment groups. Histopathological observations were also in correlation with the biochemical parameters. Thus, ferulic acid and ascorbic acid significantly counteracted the pronounced oxidative stress effect of ISO by the inhibition of lipid peroxidation, restoration of antioxidant status, and myocardial marker enzymes levels. In conclusion, these findings indicate the synergistic protective effect of ferulic acid and ascorbic acid on lipid peroxidation and antioxidant defense system during ISO-induced myocardial infarction and associated oxidative stress in rats.
71 citations
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TL;DR: Vitamin C pre-treatment protected ovary and granulosa cells from the deleterious effects of Cr(VI) toxicity, both in vivo and in vitro.
71 citations
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TL;DR: A possible route for green synthesis of gold nanoparticles (AuNPs) using leaf extract of Mimosa pudica and its anticancer efficacy in the treatment of breast cancer cell lines is studied.
70 citations
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TL;DR: Two multi-centre prospective cohort studies in Africa that assess the prevalence and incidence of HIV in people using the first-line ART treatment and patients with very different backgrounds and disease characteristics are discussed.
Abstract: This article discusses two multi-centre prospective cohort studies in Africa that assess the prevalence and incidence of HIV in people using the first-line ART treatment. Participants are enrolled in the study for approximately 18 months after which new participants are recruited. The HIV positive people in the study are evaluated during their regular clinic visits. Researchers are collecting information about various HIV subtypes in the affected population incidence of duel infections and disease progression and response to treatment. Due to the various clinics involved in the study the study benefits from a large number of patients with very different backgrounds and disease characteristics.
70 citations
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TL;DR: In this article, the corrosion inhibition of brass in 0.2 m NaCl in the presence of 2-mercaptobenzothiazole (MBT) and polyoxyethylene sorbitan monooleate (Tween-80) was investigated using potentiodynamic polarization, X-ray photoelectron spectroscopy and inductively coupled plasma analysis.
70 citations
Authors
Showing all 8535 results
Name | H-index | Papers | Citations |
---|---|---|---|
David A. Kass | 127 | 580 | 58747 |
Viswanathan Mohan | 110 | 964 | 64896 |
Sridevi Devaraj | 85 | 365 | 21831 |
Raghavan Srinivasan | 80 | 959 | 37821 |
Muthupandian Ashokkumar | 76 | 511 | 20771 |
K.V. Rajagopalan | 71 | 223 | 15129 |
Rajasekhar Balasubramanian | 65 | 276 | 13854 |
Savarimuthu Ignacimuthu | 64 | 498 | 17752 |
Pappannan Thiyagarajan | 59 | 245 | 10650 |
Ravi Subrahmanyan | 59 | 353 | 14244 |
Fritz Scholz | 55 | 385 | 11420 |
M. Lakshmanan | 54 | 533 | 13357 |
Nagarajan Selvamurugan | 52 | 153 | 9477 |
Kumarasamy Thangaraj | 47 | 361 | 11869 |
Suniti Solomon | 46 | 191 | 6400 |