Institution
University of Saskatchewan
Education•Saskatoon, Saskatchewan, Canada•
About: University of Saskatchewan is a education organization based out in Saskatoon, Saskatchewan, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 25021 authors who have published 52579 publications receiving 1483049 citations. The organization is also known as: USask.
Papers published on a yearly basis
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TL;DR: A review of recent advances in medical imaging using the adversarial training scheme with the hope of benefiting researchers interested in this technique.
1,053 citations
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TL;DR: It is shown that extremely simple adaptive load sharing policies, which collect very small amounts of system state information and which use this information in very simple ways, yield dramatic performance improvements.
Abstract: Rather than proposing a specific load sharing policy for implementation, the authors address the more fundamental question of the appropriate level of complexity for load sharing policies. It is shown that extremely simple adaptive load sharing policies, which collect very small amounts of system state information and which use this information in very simple ways, yield dramatic performance improvements. These policies in fact yield performance close to that expected from more complex policies whose viability is questionable. It is concluded that simple policies offer the greatest promise in practice, because of their combination of nearly optimal performance and inherent stability.
1,041 citations
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International Crops Research Institute for the Semi-Arid Tropics1, CGIAR2, Beijing Genomics Institute3, National Research Council4, Iowa State University5, University of California, Davis6, University of Saskatchewan7, University of Córdoba (Spain)8, University of Georgia9, University of Arizona10, National Center for Genome Resources11, Commonwealth Scientific and Industrial Research Organisation12, Indian Council of Agricultural Research13, Curtin University14, University of Queensland15, Goethe University Frankfurt16, University of Western Australia17, University of Copenhagen18
TL;DR: This work reports the ∼738-Mb draft whole genome shotgun sequence of CDC Frontier, a kabuli chickpea variety, which contains an estimated 28,269 genes, and identifies targets of both breeding-associated genetic sweeps and breeding- associated balancing selection.
Abstract: Chickpea (Cicer arietinum) is the second most widely grown legume crop after soybean, accounting for a substantial proportion of human dietary nitrogen intake and playing a crucial role in food security in developing countries. We report the ~738-Mb draft whole genome shotgun sequence of CDC Frontier, a kabuli chickpea variety, which contains an estimated 28,269 genes. Resequencing and analysis of 90 cultivated and wild genotypes from ten countries identifies targets of both breeding-associated genetic sweeps and breeding-associated balancing selection. Candidate genes for disease resistance and agronomic traits are highlighted, including traits that distinguish the two main market classes of cultivated chickpea—desi and kabuli. These data comprise a resource for chickpea improvement through molecular breeding and provide insights into both genome diversity and domestication.
1,014 citations
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TL;DR: Two‐way analysis of covariance demonstrated significant physical activity and gender main effects (but no interaction) for PBMCV, for BMC accrued for 2 years around peak velocity, and for BMC at 1 year post‐PBMCV for the TB and femoral neck and for physical activity but not gender at the LS.
Abstract: To investigate the influence of physical activity on bone mineral accrual during the adolescent years, we analyzed 6 years of data from 53 girls and 60 boys. Physical activity, dietary intakes, and anthropometry were measured every 6 months and dual-energy X-ray absorptiometry scans of the total body (TB), lumbar spine (LS), and proximal femur (Hologic 2000, array mode) were collected annually. Distance and velocity curves for height and bone mineral content (BMC) were fitted for each child at several skeletal sites using a cubic spline procedure, from which ages at peak height velocity (PHV) and peak BMC velocity (PBMCV) were identified. A mean age- and gender-specific standardized activity (Z) score was calculated for each subject based on multiple yearly activity assessments collected up until age of PHV. This score was used to identify active (top quartile), average (middle 2 quartiles), or inactive (bottom quartile) groups. Two-way analysis of covariance, with height and weight at PHV controlled for, demonstrated significant physical activity and gender main effects (but no interaction) for PBMCV, for BMC accrued for 2 years around peak velocity, and for BMC at 1 year post-PBMCV for the TB and femoral neck and for physical activity but not gender at the LS (all p < 0.05). Controlling for maturational and size differences between groups, we noted a 9% and 17% greater TB BMC for active boys and girls, respectively, over their inactive peers 1 year after the age of PBMCV. We also estimated that, on average, 26% of adult TB bone mineral was accrued during the 2 years around PBMCV.
998 citations
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TL;DR: It is indicated that celecoxib is an effective agent for the prevention of colorectal adenomas but, because of potential cardiovascular events, cannot be routinely recommended for this indication.
Abstract: Background Studies showing that drugs that inhibit cyclooxygenase-2 (COX-2) reduce the number of colorectal adenomas in animals and patients with familial adenomatous polyposis suggest that COX-2 inhibitors may also prevent sporadic colorectal neoplasia. Methods We randomly assigned patients who had adenomas removed before study entry to receive placebo (679 patients) or 200 mg (685 patients) or 400 mg (671 patients) of celecoxib twice daily. Randomization was stratified for the use of low-dose aspirin. Follow-up colonoscopies were performed at one and three years after randomization. The occurrence of newly detected colorectal adenomas was compared among the groups with the life-table extension of the Mantel–Haenszel test. Results Follow-up colonoscopies were completed at year 1 in 89.5 percent of randomized patients, and at year 3 in 75.7 percent. The estimated cumulative incidence of the detection of one or more adenomas by year 3 was 60.7 percent for patients receiving placebo, as compared with 43.2 p...
988 citations
Authors
Showing all 25277 results
Name | H-index | Papers | Citations |
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Tomas Hökfelt | 158 | 1033 | 95979 |
Frederick Wolfe | 119 | 417 | 101272 |
Christopher G. Goetz | 116 | 651 | 59510 |
John P. Giesy | 114 | 1162 | 62790 |
Helmut Kettenmann | 104 | 380 | 40211 |
Paul M. O'Byrne | 104 | 605 | 56520 |
Susan S. Taylor | 104 | 518 | 42108 |
Keith A. Hobson | 103 | 653 | 41300 |
Mark S. Tremblay | 100 | 541 | 43843 |
James F. Fries | 100 | 369 | 83589 |
Gordon McKay | 97 | 661 | 61390 |
Jonathan D. Adachi | 96 | 589 | 31641 |
Wenjun Zhang | 96 | 976 | 38530 |
William C. Dement | 96 | 340 | 43014 |
Chris Ryan | 95 | 971 | 34388 |