scispace - formally typeset
Search or ask a question
Institution

University of Western Australia

EducationPerth, Western Australia, Australia
About: University of Western Australia is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 29613 authors who have published 87405 publications receiving 3064466 citations. The organization is also known as: UWA & University of WA.


Papers
More filters
Journal ArticleDOI
TL;DR: Halophytes, plants that survive to reproduce in environments where the salt concentration is around 200 mm NaCl or more, constitute about 1% of the world's flora and research should be concentrated on a number of 'model' species that are representative of the various mechanisms that might be involved in tolerance.
Abstract: Halophytes, plants that survive to reproduce in environments where the salt concentration is around 200 mM NaCl or more, constitute about 1% of the worlds flora. Some halophytes show optimal growth in saline conditions; others grow optimally in the absence of salt. However, the tolerance of all halophytes to salinity relies on controlled uptake and compartmentalization of Na+, K+ and Cl- and the synthesis of organic compatible solutes, even where salt glands are operative. Although there is evidence that different species may utilize different transporters in their accumulation of Na+, in general little is known of the proteins and regulatory networks involved. Consequently, it is not yet possible to assign molecular mechanisms to apparent differences in rates of Na+ and Cl- uptake, in root-to-shoot transport (xylem loading and retrieval), or in net selectivity for K+ over Na+. At the cellular level, H+-ATPases in the plasma membrane and tonoplast, as well as the tonoplast H+-PPiase, provide the transmembrane proton motive force used by various secondary transporters. The widespread occurrence, taxonomically, of halophytes and the general paucity of information on the molecular regulation of tolerance mechanisms persuade us that research should be concentrated on a number of model species that are representative of the various mechanisms that might be involved in tolerance.

2,127 citations

Journal ArticleDOI
Rudi Appels1, Rudi Appels2, Kellye Eversole, Nils Stein3  +204 moreInstitutions (45)
17 Aug 2018-Science
TL;DR: This annotated reference sequence of wheat is a resource that can now drive disruptive innovation in wheat improvement, as this community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
Abstract: An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.

2,118 citations

Journal ArticleDOI
16 Mar 2017-Nature
TL;DR: The distinctive geographic footprints of recurrent bleaching on the Great Barrier Reef in 1998, 2002 and 2016 were determined by the spatial pattern of sea temperatures in each year, suggesting that local protection of reefs affords little or no resistance to extreme heat.
Abstract: During 2015–2016, record temperatures triggered a pan-tropical episode of coral bleaching, the third global-scale event since mass bleaching was first documented in the 1980s. Here we examine how and why the severity of recurrent major bleaching events has varied at multiple scales, using aerial and underwater surveys of Australian reefs combined with satellite-derived sea surface temperatures. The distinctive geographic footprints of recurrent bleaching on the Great Barrier Reef in 1998, 2002 and 2016 were determined by the spatial pattern of sea temperatures in each year. Water quality and fishing pressure had minimal effect on the unprecedented bleaching in 2016, suggesting that local protection of reefs affords little or no resistance to extreme heat. Similarly, past exposure to bleaching in 1998 and 2002 did not lessen the severity of bleaching in 2016. Consequently, immediate global action to curb future warming is essential to secure a future for coral reefs.

2,073 citations

Journal ArticleDOI
TL;DR: In a longitudinal study of patients with NAFLD, fibrosis stage, but no other histologic features of steatohepatitis, were associated independently with long-term overall mortality, liver transplantation, and liver-related events.

2,061 citations

Journal ArticleDOI
TL;DR: In this article, the authors investigate the ability of strindicated interfcices between components in product design to embed coordination of product development processes and develop concepts of modularity in product and organization designs based on nearly decoffnposable systems.
Abstract: This pczper investigcztes irzterrelationslzi~~s of product design, orgcznization design, processes for leartlirzg and managing knowledge, arzd competitive strategy. This paper uses the principles of nearly decotnposable systems to investigate the ability of strind(irdized interfcices between components in cz product design to embed coordination of product development processes. Embedded coordination creates 'hierczrchical coordination' without the need to continually exercise authority-erzcrblirlg effective coordination of processes without the tight coupling of orgcznizationczl structures. We develop concepts of modularity in product and organization designs based orz smndcirdized component and organization interjczces. Modular product architec- tures create information structures that provide the 'glue' that holds together the loosely coupled parts of a modular orgatzizatiorz design. By fczcilitriting loose coupling, modularity can czlso reduce the cost and dyficulty of adaptive coordination, thereby incrensing the strategic flexibility of firms to respond to erzvironmentnl change. Modularity in product and organizcztion designs therefore etznbles cz new strcitegic approach to the management of knowledge based on cztz irztentionczl, carefully mcznaged loose coupling of (I firm's learning processes czt architec- tural cznd comporzent levels of product crecztiorz processes.

2,047 citations


Authors

Showing all 29972 results

NameH-indexPapersCitations
Nicholas G. Martin1921770161952
Cornelia M. van Duijn1831030146009
Kay-Tee Khaw1741389138782
Steven N. Blair165879132929
David W. Bates1591239116698
Mark E. Cooper1581463124887
David Cameron1541586126067
Stephen T. Holgate14287082345
Jeremy K. Nicholson14177380275
Xin Chen1391008113088
Graeme J. Hankey137844143373
David Stuart1361665103759
Joachim Heinrich136130976887
Carlos M. Duarte132117386672
David Smith1292184100917
Network Information
Related Institutions (5)
University of Queensland
155.7K papers, 5.7M citations

98% related

University of Melbourne
174.8K papers, 6.3M citations

97% related

University of Sydney
187.3K papers, 6.1M citations

97% related

University of British Columbia
209.6K papers, 9.2M citations

92% related

University of Manchester
168K papers, 6.4M citations

92% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023138
2022656
20215,967
20205,589
20195,452
20184,923