IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
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This article is published in Journal of Clinical Pathology.The article was published on 1980-01-01 and is currently open access. It has received 3514 citations till now.read more
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Mutagenicity of three disinfection by-products: di- and trichloroacetic acid and chloral hydrate in L5178Y/TK +/- (-)3.7.2C mouse lymphoma cells.
TL;DR: These three chemicals were evaluated for their potential to induce micronuclei and aberrations as well as mutations in L5178Y/TK +/- (-)3.7C mouse lymphoma cells and it seems reasonable to postulate that mutational events are involved in the etiology of the observed mouse liver tumors induced by DCA at drinking water doses.
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Antioxidant activity of Potentilla fulgens: An alpine plant of western Himalaya
Vikas Jaitak,Kapil Sharma,Kalpana Kalia,Neeraj Kumar,Hirendra Pratap Singh,Vijay K. Kaul,Bikram Singh +6 more
TL;DR: In this article, the antioxidant properties of methanol extract, fractions and isolated compounds from the roots of Potentilla fulgens Lodd were evaluated by three in vitro experiments, namely, ABTS, DPPH, and FRAP assays.
Journal Article
Influence of Intestinal Bacteria, Sex of the Animal, and Position of the Nitro Group on the Hepatic Genotoxicity of Nitrotoluene Isomers in Vivo
TL;DR: It is demonstrated that the mononitrotoluenes display marked isomeric differences in their genotoxic potential, indicate the obligatory role of intestinal bacteria in the metabolic activation of 2NT, and show that the genot toxic potential of 2 NT is dependent upon the sex of the animal under study.
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Low dose exposure to sodium arsenite synergistically interacts with UV radiation to induce mutations and alter DNA repair in human cells
TL;DR: The data suggest that pre-treatment of human cells with arsenic impairs the nucleotide excision repair pathway and leads to enhanced UV mutagenesis, and that As(III) is mutagenic only at high doses at the TK locus.
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Occurrence of antibiotics residues in hospital wastewater, wastewater treatment plant, and in surface water in Nairobi County, Kenya.
TL;DR: Continuous monitoring of antibiotics residues in wastewater, surface water, and other environmental matrices is very important due to their adverse health and environmental effects and is useful in designing strategies for antibiotics pollution control and also in policy formulation.