IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
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This article is published in Journal of Clinical Pathology.The article was published on 1980-01-01 and is currently open access. It has received 3514 citations till now.read more
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Overview of analysis of carcinogenic and/or mutagenic metals in biological and environmental samples. I. Arsenic, beryllium, cadmium, chromium and selenium.
TL;DR: The principal objective of this overview is to highlight the more recent trends and state-of-the-art methodologies for the determination of arsenic, beryllium, cadmium, chromium and selenium (in their various forms) in environmental compartments such as air, water, soil and in human tissues.
Journal Article
Albumin Adducts of Benzene Oxide and 1,4-Benzoquinone as Measures of Human Benzene Metabolism
Stephen M. Rappaport,Suramya Waidyanatha,Qingshan Qu,Roy E. Shore,Ximei Jin,Beverly S. Cohen,Lung Chi Chen,Assieh A. Melikian,Guilan Li,Songnian Yin,Huifang Yan,Bohong Xu,Ruidong Mu,Yuying Li,Xiaoling Zhang,Keqi Li +15 more
TL;DR: Albumin adducts can be used to investigate the dispositions of reactive metabolites of procarcinogens in humans, provided that exposures are adequately characterized in the month preceding blood collection.
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Determination of tar, nicotine, and carbon monoxide yields in the mainstream smoke of selected international cigarettes.
Antonia M. Calafat,Gregory M. Polzin,J Saylor,Patricia Richter,David L. Ashley,Clifford H. Watson +5 more
TL;DR: Analysis of the smoke deliveries suggested that cigarettes from the Eastern Mediterranean, Southeast Asia, and Western Pacific WHO regions tended to have higher tar, nicotine, and CO smoke deliveries than did brands from the European, American, or African WHO regions surveyed.
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Using three-dimensional quantitative structure-activity relationships to examine estrogen receptor binding affinities of polychlorinated hydroxybiphenyls.
TL;DR: Comparative molecular field analysis (CoMFA), a three-dimensional quantitative structure-activity relationship (QSAR) paradigm, is used to examine the underlying structural properties of ortho-chlorinated hydroxybiphenyl analogs known to bind to the estrogen receptor, and indicates a high degree of internal predictability for the molecules included in the training data set.
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Human sulphotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissue
TL;DR: It is demonstrated that expression of human SULTs in bacterial and mammalian target cells reinforces the mutagenic activity of aristolochic acids and the possibility that reactive sulphuric acid conjugates produced in other tissues are transferred to kidney and ureter.