IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
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This article is published in Journal of Clinical Pathology.The article was published on 1980-01-01 and is currently open access. It has received 3514 citations till now.read more
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Induction of hyperglycaemia in zebrafish (Danio rerio) leads to morphological changes in the retina
TL;DR: The results suggest that zebrafish may be used as an animal model in which to study diabetic retinopathy, similar to that seen in other animal models of diabetes and in diabetic patients.
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Quantification of the co-mutagenic β-carbolines, norharman and harman, in cigarette smoke condensates and cooked foods
Yukari Totsuka,Hirofumi Ushiyama,Junko Ishihara,Rashmi Sinha,Sumio Goto,Takashi Sugimura,Keiji Wakabayashi +6 more
TL;DR: Co-mutagenic beta-carbolines, such as norharman and harman, were quantified in mainstream and sidestream smoke condensates of six Japanese brands of cigarettes, and also in 13 kinds of cooked foods, using a combination of blue cotton treatment and HPLC, suggesting that humans are exposed to norHarman and Harman in daily life to a larger extent than to HCAs.
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Brominated flame retardants induce intragenic recombination in mammalian cells.
TL;DR: The findings indicate that the modern additives to plastic, i.e., HBCD and PBDEs, as well as the plastic monomer BCPS may have the same effect to human health as DDT and PCBs, in terms of inducing genetic recombination, which is known to provoke a number of diseases, including cancer.
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Toxicology and risk assessment of acrolein in food.
Klaus Abraham,Susanne Andres,Richard Palavinskas,Katharina Berg,Klaus E. Appel,Alfonso Lampen +5 more
TL;DR: It is concluded that a health risk seems to be unlikely of acrolein exposure via food due to analytical difficulties and the lack of reliable content measurements, and rough estimates of ac rolein exposure in the range of a few μg/kg body weight/day.
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Polycyclic aromatic hydrocarbons in the surface soils from outskirts of Beijing, China.
TL;DR: The selected marked compounds, a principal component analysis (PCA) and special PAHs compound ratios suggest the pyrogenic origins, especially traffic exhausts, are the dominant sources ofPAHs in Beijing outskirts soils.