IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
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This article is published in Journal of Clinical Pathology.The article was published on 1980-01-01 and is currently open access. It has received 3514 citations till now.read more
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Journal ArticleDOI
Promoting effects of dimethylarsinic acid on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in rats.
Hideki Wanibuchi,Shinji Yamamoto,Hua Chen,Kaoru Yoshida,Ginji Endo,Takaaki Hori,Shoji Fukushima +6 more
TL;DR: The results suggest that DMA has the potential to promote rat urinary bladder carcinogenesis and one of the mechanisms involved is its stimulation of cell proliferation in the urinary bladder epithelium.
Journal ArticleDOI
The reduced expression and aberrant methylation of p16(INK4a) in chromate workers with lung cancer.
Kazuya Kondo,Yuji Takahashi,Yukiko Hirose,Taeko Nagao,Masaru Tsuyuguchi,Masato Hashimoto,Atsushi Ochiai,Yasumasa Monden,Akira Tangoku +8 more
TL;DR: It is speculated that not only genetic but also epigenetic alterations are involved in the carcinogenesis due to chromium.
Journal ArticleDOI
V79-hCYP2E1-hSULT1A1, a cell line for the sensitive detection of genotoxic effects induced by carbohydrate pyrolysis products and other food-borne chemicals.
TL;DR: Induction of SCE in V79-hCYP2E1-hSULT1A1 cells may be useful in the genotoxicity testing of preparations of heated food and in their bioassay-directed fractionation.
Journal ArticleDOI
Dietary Benzo[a]Pyrene Intake and Risk of Colorectal Adenoma
TL;DR: Evidence is provided that dietary BaP plays a role in colorectal adenoma etiology and is more strongly associated with BaP intake estimated from all foods.
Book ChapterDOI
Arsenic induces oxidative DNA damage in mammalian cells.
TL;DR: Evidence is provided that reactive oxygen species play an important causal role in the genotoxicity of arsenic in mammalian cells and that oxyradicals may be involved in the mutagenic process.