IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
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This article is published in Journal of Clinical Pathology.The article was published on 1980-01-01 and is currently open access. It has received 3514 citations till now.read more
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Chemical mutagenesis testing in Drosophila. IX. Results of 50 coded compounds tested for the national toxicology program
TL;DR: Fifty chemicals were tested for mutagenic activity in post-meiotic and meiotic germ cells of male Drosophila melanogaster using the sex-linked recessive lethal (SLRL) assay and five of these, including 1,4-butanediol diglycidyl ether, 2,2-dimethyl vinyl chloride, hexamethylphosphoramide, isopropyl glycidyl Ether, and urethane induced reciprocal translocations.
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Tumour promotion by tcdd in skin of hrs/j hairless mice.
TL;DR: In HRS/J hairless mice, tumour promotion by TCDD elicits the same incidence and multiplicity of skin papillomas as does the classical tumour .promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), but at l/100th the dose.
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Concentration and profile of 22 urinary polycyclic aromatic hydrocarbon metabolites in the US population.
Zheng Li,Courtney D. Sandau,Lovisa C. Romanoff,Samuel P. Caudill,Andreas Sjödin,Larry L. Needham,Donald G. Patterson +6 more
TL;DR: The use of 1-PYR as a useful surrogate representing PAH exposure is supported, and log-transformed concentrations for major detectable OH-PAHs were significantly correlated with each other.
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Aggregate exposures of nine preschool children to persistent organic pollutants at day care and at home
TL;DR: It is found that the indoor exposures were greater than those outdoors, that exposures at day care and at home were of similar magnitudes, and that diet contributed greatly to the exposures.
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Systematic review of the relationship between family history and lung cancer risk
TL;DR: A systematic review of studies of the relationship between family history and risk of lung cancer and a meta-analysis of risk estimates shows a significantly increased lung cancer risk associated with having an affected relative.