IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
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This article is published in Journal of Clinical Pathology.The article was published on 1980-01-01 and is currently open access. It has received 3514 citations till now.read more
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Vitamin A supplements, fried foods, fat and urothelial cancer. A case-referent study in Stockholm in 1985-87.
TL;DR: In this paper, a population-based case-referent study of urothelial cancer in Stockholm during 1985-87, information was obtained from 78% of 418 identified cases and 77% of 511 selected referents.
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Assessment of the human exposure to heterocyclic amines.
TL;DR: The method was employed in an elderly population in Stockholm to estimate the daily mean intake of the five heterocyclic amines 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-Amino-1-methyl-6-phenylimidazation (MeIQ), DiMeIQx and PhIP, with the total daily intake ranging from none to 1816 ng, which is well below estimates reported previously.
Journal Article
Oxidative DNA Damage and Apoptosis Induced by Benzene Metabolites
Yusuke Hiraku,Shosuke Kawanishi +1 more
TL;DR: Results suggest that these benzene metabolites cause DNA damage through H2O2 generation in cells, preceding internucleosomal DNA fragmentation leading to apoptosis, which might be dependent on the intensity of DNA damage and the ability to repair DNA.
Toxicological profile for selenium
TL;DR: This edition supersedes any previously released draft or final profile for selenium and is a unique compilation of toxicological information on a given hazardous substance.
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Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells.
TL;DR: Comparisons of the present results with data from earlier experiments indicate that the Hep G2/SCGE assay enables the detection of genotoxins including compounds which give misleading results in other in vitro genotoxicity tests and appears to be an alternative to tests with primary liver cells from laboratory animals.