IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
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This article is published in Journal of Clinical Pathology.The article was published on 1980-01-01 and is currently open access. It has received 3514 citations till now.read more
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Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines.
Rahat Ali,Rahat Ali,Roberta A. Mittelstaedt,Joseph G. Shaddock,Wei Ding,Javed A. Bhalli,Qaiser M. Khan,Robert H. Heflich +7 more
TL;DR: Micronucleus induction by OTA is evaluated in comparison with its ability to induce cytotoxicity and DNA damage in two mammalian cell lines, CHO-K1-BH(4) Chinese hamster ovary cells and TK6 human lymphoblastoid cells to suggest its involvement in producing OTA-induced clastogenicity and aneugenicity is investigated.
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Occupational risk factors for brain cancer in Canada.
TL;DR: An increased risk of brain cancer might be associated with exposure to asbestos, benzene, mineral or lubricating oil, isopropyl oil, and wood dust and with following occupations: teaching; protective service; metal processing and related jobs, and metal shaping and forming.
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Toxicity of vinyl chloride and poly(vinyl chloride): a critical review.
TL;DR: The evidence for a carcinogenic risk has been extended to jobs associated with poly(vinyl chloride) exposure and the target organs for VC now clearly include the liver, brain and the lung, and probably the lymphohematopoietic system.
Journal Article
The use of 4-aminobiphenyl hemoglobin adducts and aromatic DNA adducts in lymphocytes of smokers as biomarkers of exposure.
Jan W. Dallinga,D. M. F. A. Pachen,S. W. P. Wijnhoven,A. Breedijk,L van 't Veer,G. Wigbout,N. van Zandwijk,L.M. Maas,E. van Agen,J.C.S. Kleinjans,F.J. van Schooten +10 more
TL;DR: Two biomarkers of exposure to cigarette smoke, 4-aminobiphenyl-hemoglobin (Hb)adducts and aromatic DNA adducts in lymphocytes, were determined from a population of 55 smokers and 4 nonsmokers and found no influence of GSTM1 and NAT2 polymorphisms on Hb adduct formation and of GSTm1 polymorphism on aromatic DNAAdduct formation.
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Ecotoxicological evaluation of the antimalarial drug chloroquine.
Jorge L. Zurita,Ángeles Jos,Ana del Peso,M. Salguero,Miguel López-Artíguez,Guillermo Repetto +5 more
TL;DR: In conclusion, CQ should be classified as harmful to aquatic organisms.