IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
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This article is published in Journal of Clinical Pathology.The article was published on 1980-01-01 and is currently open access. It has received 3514 citations till now.read more
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Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention
TL;DR: Three prevention-related topics are discussed: human uptake of tobacco carcinogens as a way of assessing risk and investigating mechanisms; individual differences in the metabolic activation and detoxification of carcinogens, which may relate to cancer susceptibility; and chemoprevention of lung cancer in smokers and ex-smokers.
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Second primary neoplasms in patients with retinoblastoma.
TL;DR: Evidence from this and other papers strongly suggests an association between retinoblastoma and malignant melanoma and the use of cyclophosphamide may increase the risk of second primary neoplasms in patients with genetic retinOBlastoma.
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Effects of low doses and low dose rates of external ionizing radiation: cancer mortality among nuclear industry workers in three countries
Elisabeth Cardis,Ethel S. Gilbert,Lucy M. Carpenter,Geoffrey R. Howe,I Kato,Bruce K. Armstrong,Valerie Beral,G Cowper,A Douglas,J. J. Fix +9 more
TL;DR: Estimates of cancer risk associated with low-dose protracted exposures obtained are compatible with a range of possibilities, from a reduction of risk at low doses, to risks twice those on which current radiation protection recommendations are based.
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Ranking possible carcinogenic hazards
TL;DR: This review discusses reasons why animal cancer tests cannot be used to predict absolute human risks, and suggests that carcinogenic hazards from current levels of pesticide residues or water pollution are likely to be of minimal concern relative to the background levels of natural substances.
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Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment
TL;DR: Overall assessment of the cancer risk of aldehydes in the diet leads to the conclusion that formaldehyde, acrolein, citral and vanillin are no dietary risk factors, and that the opposite may be true for acetaldehyde, crotonaldehyde and furfural.