PatentDOI
Peripheral nerve regeneration
James W. Fawcett,Roger J. Keynes +1 more
TLDR
Basal lamina grafts for reconnecting severed nerves are prepared from muscle by removing cellular material therefrom while preserving the tubular structure of the basal lamina, eventually reestablishing nerve function through the regenerated graft.Abstract:
Basal lamina grafts for reconnecting severed nerves are prepared from muscle by removing cellular material therefrom while preserving the tubular structure of the basal lamina. When connected to nerve stumps the basal lamina surfaces promote axon regeneration therethrough, eventually reestablishing nerve function through the regenerated graft.read more
Citations
More filters
Patent
Method for connecting nerves via a side-to-side epineurial window using artificial conduits
TL;DR: In this paper, a bridging element between a first epineurial window on a donor nerve and a second epineural window on the recipient nerve was used to repair a muscle via side-to-side neurorraphy.
Journal ArticleDOI
Spinal Cord Injury Repair Strategies
TL;DR: The vast body of work presently underway to reverse spinal cord injury is examined and an understanding of the pathology is of first and foremost importance before solutions can be reliably sought.
Journal ArticleDOI
Long-term Outcomes Following Temperature-Controlled Radiofrequency Neurolysis for the Treatment of Chronic Rhinitis
Dale Ehmer,Chad M. McDuffie,John B. McIntyre,Bryan M. Davis,Neelesh H. Mehendale,John H. Willis,Jeremy Watkins,Venkata V. Kakarlapudi +7 more
TL;DR: Temperature-controlled radiofrequency neurolysis results in a significant and durable reduction in the symptom burden of chronic rhinitis and patients reported improved quality of life through 24 months postprocedure.
Dissertation
Maintenance de la myeline peripherique : physiologie et physiopathologie
TL;DR: In this article, a nouvelle methode for the implication of different genes dans the maintenance of the myeline peripherique was proposed, and the use of siRNA modifies for inhyber les genes candidats without utiliser de reactif de transfection.
Journal ArticleDOI
Regenerative Capacity and Histomorphometric Changes in Rat Sciatic Nerve Following Experimental Neurotmesis
Deniele Bezerra Lós,Karyne Albino Novaes,Filipe Barbosa Cunha de Miranda,Kamilla Dinah Santos de Lira,Rodrigo Fragoso de Andrade,Sílvia Regina Arruda de Moraes +5 more
TL;DR: This estudio fue evaluar histomorfometricamente el grado de madurez del tejido nervioso y los posibles cambios microscopicos en los segmentos nerviosos recien formados 60 dias despues of the neurotmesis experimental en el nervio ciatico de ratas.
References
More filters
Journal ArticleDOI
The nerve growth factor 35 years later
TL;DR: The field of experimental embryology, which had been enthusiastically acclaimed in the mid-thirties, suffered from a sharp decrease in the enthusiasm that had inflamed the pioneers in this field, ever since R. G. Harrison delivered his celebrated lecture at the Royal Society in London in 1935.
Journal ArticleDOI
Structural characterization and biological functions of fibroblast growth factor
TL;DR: As expected from their structural relationship, both FGF and aFGF interact with the same receptor (7), thereby having similar, if not identical, properties.
Journal ArticleDOI
Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection.
TL;DR: In situ hybridization experiments demonstrated that after transection all nonneuronal cells express mRNANGF and not only those ensheathing the nerve fibers of NGF-responsive neurons, and the volume is too small to fully replace the lacking supply from the periphery.
Journal ArticleDOI
Experiments on the Section of the Glossopharyngeal and Hypoglossal Nerves of the Frog, and Observations of the Alterations Produced Thereby in the Structure of Their Primitive Fibres
TL;DR: The object of the present observations is to describe certain alterations which take place in the elementary fibres of the nerve after they have been removed from their connection with the brain or spinal marrow.
Journal ArticleDOI
Nerve regeneration in silicone chambers : influence of gap length and of distal stump components
Göran Lundborg,Lars B. Dahlin,Nils Danielsen,Richard H. Gelberman,Frank M. Longo,Henry C. Powell,Silvio Varon +6 more
TL;DR: Observations confirm that the distal stump influences proximal regeneration and indicate that this influence can act only over a limited distance or volume.