Journal ArticleDOI
The influence of diet on the gut microbiota.
TLDR
The current 'omic era promises rapid progress towards understanding how diet can be used to modulate the composition and metabolism of the gut microbiota, allowing researchers to provide informed advice, that should improve long-term health status.About:
This article is published in Pharmacological Research.The article was published on 2013-03-01. It has received 789 citations till now. The article focuses on the topics: Gut flora & Population.read more
Citations
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Colonic bacterial composition in Parkinson's disease.
Ali Keshavarzian,Stefan J. Green,Phillip A. Engen,Robin M. Voigt,Ankur Naqib,Christopher B. Forsyth,Ece Mutlu,Kathleen M. Shannon +7 more
TL;DR: It is shown that Parkinson's disease (PD) patients have alpha‐synuclein aggregation in their colon with evidence of colonic inflammation, and dysbiosis might be the mechanism of neuroinflammation that leads to α‐Syn misfolding and PD pathology.
Journal ArticleDOI
Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling
Robert Caesar,Valentina Tremaroli,Petia Kovatcheva-Datchary,Patrice D. Cani,Fredrik Bäckhed,Fredrik Bäckhed +5 more
TL;DR: It is shown that mice fed lard for 11 weeks have increased Toll-like receptor activation and WAT inflammation and reduced insulin sensitivity compared with mice fed fish oil and that phenotypic differences between the dietary groups can be partly attributed to differences in microbiota composition.
Journal ArticleDOI
Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications
Dorna Davani-Davari,Manica Negahdaripour,Iman Karimzadeh,Mostafa Seifan,Milad Mohkam,Seyed Jalil Masoumi,Aydin Berenjian,Younes Ghasemi +7 more
TL;DR: Health benefits of prebiotics and their safety, as well as their production and storage advantages compared to probiotics, they seem to be fascinating candidates for promoting human health condition as a replacement or in association with probiotics.
Journal ArticleDOI
The effect of host genetics on the gut microbiome
Marc Jan Bonder,Alexander Kurilshikov,Alexander Kurilshikov,Ettje F. Tigchelaar,Zlatan Mujagic,Floris Imhann,Arnau Vich Vila,Patrick Deelen,Tommi Vatanen,Tommi Vatanen,Melanie Schirmer,Melanie Schirmer,Sanne P. Smeekens,Daria V. Zhernakova,Soesma A Jankipersadsing,Martin Jaeger,Marije Oosting,María Carmen Cenit,Ad A.M. Masclee,Morris A. Swertz,Yang Li,Vinod Kumar,Leo A. B. Joosten,Hermie J. M. Harmsen,Rinse K. Weersma,Lude Franke,Marten H. Hofker,Ramnik J. Xavier,Daisy Jonkers,Mihai G. Netea,Cisca Wijmenga,Jingyuan Fu,Alexandra Zhernakova +32 more
TL;DR: The results demonstrate the importance of understanding host–microbe interactions to gain better insight into human health and demonstrate the influence of host genetics on microbial species, pathways and gene ontology categories on the basis of metagenomic sequencing in 1,514 subjects.
Journal ArticleDOI
The Controversial Role of Human Gut Lachnospiraceae.
Mirco Vacca,Giuseppe Celano,Francesco Maria Calabrese,Piero Portincasa,Marco Gobbetti,Maria De Angelis +5 more
TL;DR: Changes in Lachnospiraceae abundances according to health and disease are discussed and how nutrients from the host diet can influence their growth and how their metabolites can, in turn, influence host physiology are analyzed.
References
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Journal ArticleDOI
A comparative in vitro investigation into the effects of cooked meats on the human faecal microbiota.
TL;DR: Interactions between ingested cooked meats and the gut microbiota may represent a novel corollary to mechanisms underlying the observed increased risk of intestinal and systemic diseases associated with high intake of certain meats/processed meats.
Journal ArticleDOI
13C tracer recovery in human stools after digestion of a fat‐rich meal labelled with [1,1,1‐13C3]tripalmitin and [1,1,1‐13C3]triolein
Laure Gabert,Cécile Vors,Corinne Louche-Pelissier,Valérie Sauvinet,Stéphanie Lambert-Porcheron,Jocelyne Drai,Martine Laville,Michel Désage,Marie-Caroline Michalski +8 more
TL;DR: The results confirm that the assessment of faecal elimination is of great importance when establishing total lipid distribution during the postprandial period and validate the analysis of cumulative tracer loss during 72 h post-tracer ingestion.
Journal Article
N-nitrosamine formation by intestinal bacteria.
Suzuki K,Mitsuoka T +1 more
TL;DR: The theory of enzymatic catalysis of N-nitrosamine formation by microorganisms is supported and the possibility of endogenous nitrosation in the digestive tract is suggested.
Journal ArticleDOI
What is dietary fibre
John H. Cummings,H N Englyst +1 more
TL;DR: Recent studies in humans have shown that the sites, rate and extent of starch digestion may be of equal importance to those of dietary fibre in explaining the aetiology and epidemiology of ‘Western’ diseases.
Journal ArticleDOI
Prebiotic inulin-type fructans: nutritional benefits beyond dietary fibre source
H. Alexiou,A. Franck +1 more
TL;DR: The aim of the present review was to highlight the nutritional benefits of inulin-type fructans, focusing on key physiological functions.
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