D
David Baltimore
Researcher at California Institute of Technology
Publications - 882
Citations - 168784
David Baltimore is an academic researcher from California Institute of Technology. The author has contributed to research in topics: RNA & Virus. The author has an hindex of 203, co-authored 876 publications receiving 162955 citations. Previous affiliations of David Baltimore include Thomas Jefferson University & Johns Hopkins University.
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Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine.
TL;DR: The Abelson murine leukaemia virus protein (P120) can become phosphorylated in vitro by [γ-32P]ATP and is linked to P120 at tyrosine, a linkage not previously reported for a phosphorylation reaction.
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Involvement of CRAF1, a relative of TRAF, in CD40 signaling
TL;DR: A yeast two-hybrid screen identified a gene, CRAF1, encoding a protein that interacts directly with the CD40 cytoplasmic tail through a region of similarity to the tumor necrosis factor-alpha (TNF-alpha) receptor-associated factors.
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The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
Shengli Hao,David Baltimore +1 more
TL;DR: It is shown that genes activated in cultured mouse fibroblasts in response to the cytokine tumor necrosis factor could be categorized into roughly three groups, each with different induction kinetics.
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Uncoupling IL-2 Signals that Regulate T Cell Proliferation, Survival, and Fas-Mediated Activation-Induced Cell Death
TL;DR: Different IL-2Rbeta chain signaling modules regulate T cell fate by stimulating growth and survival or by promoting apoptosis.
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Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice.
TL;DR: It is shown that mice lacking both I kappa B alpha and the p50 subunit of NF-kappa B show a dramatically delayed onset of abnormalities, and hematopoietic cells from these mice exhibit severe runting, skin defects, and extensive granulopoiesis postnatally.