D
David Baltimore
Researcher at California Institute of Technology
Publications - 882
Citations - 168784
David Baltimore is an academic researcher from California Institute of Technology. The author has contributed to research in topics: RNA & Virus. The author has an hindex of 203, co-authored 876 publications receiving 162955 citations. Previous affiliations of David Baltimore include Thomas Jefferson University & Johns Hopkins University.
Papers
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Journal ArticleDOI
Nucleotide Sequences of Human Globin Messenger RNA
Charles A. Marotta,Bernard G. Forget,Sherman M. Weissman,Inder M. Verma,Ronald P. McCaffrey,David Baltimore +5 more
TL;DR: The fingerprint pattern obtained from ribonuclease T1 digests of human 10S globin complementary RNA was specific and reproducible as discussed by the authors, and different patterns were obtained from digests from rabbit, duck, mouse, and rabbit complementary RNA, labeled in vitro with 125I or with [γ-32P]ATP.
Journal ArticleDOI
Discovering NF-κB
TL;DR: David Baltimore recalls the experiments that led to the discovery of the NF-kappaB transcription factor more than 20 years ago.
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Dual mechanisms by which miR-125b represses IRF4 to induce myeloid and B-cell leukemias.
Alex Yick Lun So,Reeshelle Sookram,Aadel A. Chaudhuri,Aadel A. Chaudhuri,Aarathi Minisandram,David Cheng,Catherine B. Xie,Ee Lyn Lim,Yvette Garcia Flores,Shuai Jiang,Jocelyn T. Kim,Christopher L. Keown,Parameswaran Ramakrishnan,David Baltimore +13 more
TL;DR: It is demonstrated that miR-125b induces myeloid leukemia by enhancing myeloids progenitor output from stem cells as well as inducing immortality, self-renewal, and tumorigenesis in myeloidal progenitors.
Journal Article
Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 1986. 46: 705-716.
Ranjan Sen,David Baltimore +1 more
TL;DR: In this paper, an electrophoretic mobility shift assay with end-labeled DNA fragments was used to characterize proteins that bind to the immunoglobulin (Ig) heavy chain and the κ light chain enhancers.
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Covalent Linkage Between Ribonucleic Acid Primer and Deoxyribonucleic Acid Product of the Avian Myeloblastosis Virus Deoxyribonucleic Acid Polymerase
TL;DR: In this paper, the existence and nature of an RNA-DNA joint was investigated by assaying for transfer of a 32P atom from an {alpha}-32P-deoxyribonucleotide to a 2'(3')-ribon nucleotide after alkaline hydrolysis of the polymerase product.