D
David Baltimore
Researcher at California Institute of Technology
Publications - 882
Citations - 168784
David Baltimore is an academic researcher from California Institute of Technology. The author has contributed to research in topics: RNA & Virus. The author has an hindex of 203, co-authored 876 publications receiving 162955 citations. Previous affiliations of David Baltimore include Thomas Jefferson University & Johns Hopkins University.
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Ordered transcription of RNA tumor virus genomes.
TL;DR: Analysis of the reaction products on polyacrylamide gels shows that the majority of DNA synthesized, especially at high concentrations of dNTPs, comprised a set of DNA chains of discrete length the longest of which cover a major fraction of the genome.
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Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells
Lili Yang,David Baltimore +1 more
TL;DR: Using TCRs specific for a model tumor antigen, it was found that the recipient mice were able to partially resist a challenge with tumor cells carrying the antigen, and complete suppression of tumor could be achieved and even tumors that had become established would regress and be eliminated after dendritic cell/peptide immunization.
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Asilomar conference on recombinant DNA molecules.
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Growth of Pseudotypes of Vesicular Stomatitis Virus with N-Tropic Murine Leukemia Virus Coats in Cells Resistant to N-Tropic Viruses
Alice S. Huang,Alice S. Huang,Peter Besmer,Peter Besmer,Louise Chu,Louise Chu,David Baltimore,David Baltimore +7 more
TL;DR: The product of the Fv-1 locus, which restricts growth of murine RNA tumor viruses, must act on an intracellular aspect of tumor virus replication, a step after attachment and penetration.
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Localization of the Major NF-κB-activating Site and the Sole TRAF3 Binding Site of LMP-1 Defines Two Distinct Signaling Motifs
TL;DR: TRAF3 binding and NF-κB activation occur through two separate motifs at opposite ends of the LMP-1 COOH-terminal sequence.