D
David Baltimore
Researcher at California Institute of Technology
Publications - 882
Citations - 168784
David Baltimore is an academic researcher from California Institute of Technology. The author has contributed to research in topics: RNA & Virus. The author has an hindex of 203, co-authored 876 publications receiving 162955 citations. Previous affiliations of David Baltimore include Thomas Jefferson University & Johns Hopkins University.
Papers
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Journal Article
RNA splicing regulates the temporal order of TNF-induced gene expression
Shengli Hao,David Baltimore +1 more
TL;DR: It is shown that the three groups initiate transcription virtually simultaneously but that delays in splicing characterize groups II and III, concluding that pre-mRNA synthesis is coordinate but splicing differences directly regulate the timing of mRNA production.
Journal ArticleDOI
The genome of Uukuniemi virus consists of three unique RNA segments
TL;DR: The presence of a 5' terminal pppAp structure in each RNA segment confirms indications from electron microscopy that the apparently circular RNA segments are not covalently closed, and supports the concept that Uukuniemi virus is a negative strand virus.
Book ChapterDOI
MicroRNAs and hematopoietic cell development.
TL;DR: How miRNAs fit into the current understanding of hematopoietic development in mammals and how breakdowns in these pathways can trigger disease are discussed.
Journal ArticleDOI
Transfection of Fibroblasts by Cloned Abelson Murine Leukemia Virus DNA and Recovery of Transmissible Virus by Recombination with Helper Virus
TL;DR: It is proposed that helper virus efficiently rescues A-MuLV from transiently transfected cells which would not otherwise have grown into foci, and it is shown that A- MuLV DNA sequences can inhibit the stable transformation of cells by other selectable DNAs.
Journal ArticleDOI
The microRNA-212/132 cluster regulates B cell development by targeting Sox4
Arnav Mehta,Arnav Mehta,Mati Mann,Jimmy L. Zhao,Jimmy L. Zhao,Georgi K. Marinov,Devdoot Majumdar,Yvette Garcia-Flores,Xiaomi Du,Erdem Erikci,Kamal Chowdhury,David Baltimore +11 more
TL;DR: A novel role for miR-212/132 as a regulator of early B cell development is uncovered and this work contributes to the understanding of B cell reprograming and its role in wound healing.