F
Feng Zhang
Researcher at Fudan University
Publications - 2715
Citations - 225233
Feng Zhang is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 172, co-authored 1278 publications receiving 181865 citations. Previous affiliations of Feng Zhang include Cincinnati Children's Hospital Medical Center & Nanjing Medical University.
Papers
More filters
Journal ArticleDOI
Biallelic mutations of CFAP251 cause sperm flagellar defects and human male infertility.
Weiyu Li,Xiaojin He,Shenmin Yang,Chunyu Liu,Huan Wu,Wangjie Liu,Mingrong Lv,Dongdong Tang,Jing Tan,Shuyan Tang,Yujie Chen,Jiajia Wang,Zhiguo Zhang,Hongyan Wang,Li Jin,Feng Zhang,Feng Zhang,Yunxia Cao +17 more
TL;DR: This study employed human whole-exome sequencing for genetic analysis and identified biallelic mutations of CFAP251 (cilia- and flagella-associated protein 251, also known as WDR66) in three (5%) of 65 Han Chinese men with MMAF and suggested that CFAP 251 is involved in flagellar functions.
Journal ArticleDOI
Dynamics and competition of CRISPR–Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing
Ya-Wen Fu,Xin-Yue Dai,Wen-Tian Wang,Zhi-Xue Yang,Juan-Juan Zhao,Jian-Ping Zhang,Wei Wen,Feng Zhang,Kerby C. Oberg,Lei Zhang,Tao Cheng,Xiao-Bing Zhang,Xiao-Bing Zhang +12 more
TL;DR: In this paper, the editing dynamics and DNA repair profiles after the delivery of Cas9-guide RNA ribonucleoprotein (RNP) with or without the adeno-associated virus serotype 6 (AAV6) as HDR donors in four cell types were explored.
Molecular Tools and Approaches for Optogenetics
Yuan Mei,Feng Zhang,Feng Zhang +2 more
TL;DR: The current state of molecular optogenetic tools and future directions of development are described, which promise to improve existing disease models and advance the understanding of psychiatric conditions.
Journal ArticleDOI
Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay.
Bernhard Schermer,Francesca Fabretti,Maximilian Damagnez,Veronica Di Cristanziano,Eva Heger,Sita Arjune,Nathan A. Tanner,Thomas Imhof,Manuel Koch,Alim Ladha,Julia Joung,Jonathan S. Gootenberg,Omar O. Abudayyeh,Volker Burst,Feng Zhang,Florian Klein,Thomas Benzing,Roman-Ulrich Müller +17 more
TL;DR: A novel multiplexed RT-LAMP approach is described and validated, which allows for fast and reliable identification of infected individuals and reveals one-step multiplexing RT- LAMP assays as a prime-option for the development of easy and cheap POC test kits.
Journal ArticleDOI
A spatial analysis of genetic structure of human populations in China reveals distinct difference between maternal and paternal lineages.
Fuzhong Xue,Fuzhong Xue,Yi Wang,Shuhua Xu,Shuhua Xu,Feng Zhang,Bo Wen,Xuesen Wu,Ming Lu,Ranjan Deka,Ji Qian,Li Jin,Li Jin +12 more
TL;DR: The spatial genetic structure and the boundary of north–south division of human populations using mtDNA data in 91 populations and Y-chromosome data in 143 populations highlights a distinct difference between spatial genetic structures of maternal and paternal lineages.