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Feng Zhang

Researcher at Fudan University

Publications -  2715
Citations -  225233

Feng Zhang is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 172, co-authored 1278 publications receiving 181865 citations. Previous affiliations of Feng Zhang include Cincinnati Children's Hospital Medical Center & Nanjing Medical University.

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FNDC5 Alleviates Hepatosteatosis by Restoring AMPK/mTOR-Mediated Autophagy, Fatty Acid Oxidation and Lipogenesis in Mice.

TL;DR: It is indicated that FNDC5 deficiency impairs autophagy and FAO and enhances lipogenesis via the AMPK/mTOR pathway and prevents the HFD-induced hyperlipemia, hepatic lipid accumulation, and impairedFAO and Autophagy in the liver.
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Plant Growth-promoting Rhizobacteria and Soybean (Glycine max (L.) Merr.) Growth and Physiology at Suboptimal Root Zone Temperatures

TL;DR: Application of plant growth-promoting rhizobacteria (PGPR) has been shown to increase legume growth and development under optimal temperature conditions, and specifically to increase nodulation and nitrogen fixation of soybean over a range of root zone temperatures (RZTs).
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Opportunities and challenges in modeling human brain disorders in transgenic primates

TL;DR: The main focus is on the creation of new primate disease models for understanding the pathological mechanisms of brain disorders and for developing new approaches to effective treatment, but it is emphasized that primate genetic models have great potential to address many fundamental questions about brain function.
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The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation.

TL;DR: It is shown that scaffold attachment factor B (SAFB), a nuclear matrix (NM)-associated protein with RNA-binding functions, modulates chromatin condensation and stabilizes heterochromatin foci in mouse cells, which may shed light on the molecular mechanisms of nuclear architecture organization.
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FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity.

TL;DR: FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in HFD-induced obesity and may be used as a therapeutic regimen for preventing inflammation and diabetes in obesity and diabetes.