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Feng Zhang

Researcher at Fudan University

Publications -  2715
Citations -  225233

Feng Zhang is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 172, co-authored 1278 publications receiving 181865 citations. Previous affiliations of Feng Zhang include Cincinnati Children's Hospital Medical Center & Nanjing Medical University.

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Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1α/NF-κB feedback pathway to inhibit liver fibrosis

TL;DR: In this paper , atractylenolide III was identified as ASCT2 inhibitor through directly bound to Asn230 of Asn 230 transporter, which was a direct target of glutaminolysis-dependent proinflammatory SASP.
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Enhancement in the active site exposure in a porphyrin-based PIL/graphene composite catalyst for the highly efficient conversion of CO2.

TL;DR: In this article , the synthesis of a PIL/graphene composite catalyst (iPOP-ZnTPy@GNFs) based on an in situ surface preparation strategy, which effectively controlled the particle size and dispersion state of ionic liquids.

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

Evangelos Evangelou, +76 more
TL;DR: Osteoarthritis is the most prevalent form of arthritis and accounts for substantial morbidity and disability, particularly in older people, and its aetiology is multifactorial with a strong postulated genetic component.
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Proteomic profiling analysis of postmenopausal osteoporosis and osteopenia identifies potential proteins associated with low bone mineral density.

TL;DR: The results suggest that postmenopausal women with low BMD have a different proteomic profile or signature, and protein alterations may play an important role in the pathogenesis of PMOP, and they may act as novel biomarkers and targets of therapeutic agents for this disease.
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Exome sequencing identified FGF12 as a novel candidate gene for Kashin-Beck disease.

TL;DR: This study suggests that FGF12 was a susceptibility gene of KBD, and provides novel clues for revealing the pathogenesis ofKBD and the biological function of FGF 12.