F
Feng Zhang
Researcher at Fudan University
Publications - 2715
Citations - 225233
Feng Zhang is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 172, co-authored 1278 publications receiving 181865 citations. Previous affiliations of Feng Zhang include Cincinnati Children's Hospital Medical Center & Nanjing Medical University.
Papers
More filters
Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
Kyungheon Lee,Jun S. Song,Ralph Weissleder,Hakho Lee,Sidi Chen,Neville E. Sanjana,Kaijie Zheng,Ophir Shalem,Xi Shi,David Scott,Jennifer Q. Pan,Feng Zhang,Phillip A. Sharp +12 more
TL;DR: This study demonstrates Cas9-based screening as a robust method to systematically assay gene phenotypes in cancer evolution in vivo and demonstrates the effect of mutations on primary tumor growth positively correlates with the development of metastases.
Journal ArticleDOI
Specific flavonoids induced nod gene expression and pre‐activated nod genes of Rhizobium leguminosarum increased pea (Pisum sativum L.) and lentil (Lens culinaris L.) nodulation in controlled growth chamber environments
TL;DR: Out of a number of signal compounds, hesperetin and naringenin were found to be the most effective plant-to-bacteria signal molecules for pea and lentil and the induction conditions, where the induction of nod genes was temperature-dependent, where nod gene induction was decreased with dropping incubation temperature.
Journal ArticleDOI
Feature parameter extraction and intelligent estimation of the State-of-Health of lithium-ion batteries
Yuanwang Deng,Hejie Ying,Jiaqiang E,Hao Zhu,Kexiang Wei,Jingwei Chen,Feng Zhang,Gaoliang Liao +7 more
TL;DR: In this work, some battery SOH relate features are selected theoretically, proved and then re-screened mathematically, thereby a model that is suitable for lithium-ion Battery SOH estimation under multi-working conditions can be built.
Journal ArticleDOI
Genetic Structure of Hmong-Mien Speaking Populations in East Asia as Revealed by mtDNA Lineages
Bo Wen,Hui Li,Song Gao,Xianyun Mao,Gao Yang,Feng Li,Feng Zhang,Yungang He,Yongli Dong,Youjun Zhang,Wenju Huang,Jianzhong Jin,Chunjie Xiao,Daru Lu,Ranajit Chakraborty,Bing Su,Ranjan Deka,Li Jin +17 more
TL;DR: The results indicate that the Hmong populations had experienced more contact with the northern East Asians, a finding consistent with historical evidence.
Journal ArticleDOI
CRISPR-Cas9–based treatment of myocilin-associated glaucoma
Ankur Jain,Gulab Zode,Ramesh B. Kasetti,Fei A. Ran,Winston X. Yan,Tasneem Putliwala Sharma,Kevin Bugge,Charles Searby,John H. Fingert,Feng Zhang,Abbot F. Clark,Val C. Sheffield +11 more
TL;DR: By disrupting the mutant myocilin gene and its function using CRISPR-Cas9, this study was able to reduce associated endoplasmic reticulum stress, lower intraocular pressure, and prevent further glaucomatous damage in mouse eyes.