F
Feng Zhang
Researcher at Fudan University
Publications - 2715
Citations - 225233
Feng Zhang is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 172, co-authored 1278 publications receiving 181865 citations. Previous affiliations of Feng Zhang include Cincinnati Children's Hospital Medical Center & Nanjing Medical University.
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Journal ArticleDOI
miR-25-3p, Positively Regulated by Transcription Factor AP-2α, Regulates the Metabolism of C2C12 Cells by Targeting Akt1.
Feng Zhang,Kun Chen,Hu Tao,Tingting Kang,Qi Xiong,Qianhui Zeng,Yang Liu,Siwen Jiang,Mingxin Chen +8 more
TL;DR: Findings suggest that miR-25-3p, positively regulated by the transcription factor AP-2α, enhances C2C12 cell metabolism by targeting the Akt1 gene.
Journal ArticleDOI
Genome‐wide association study and identification of chromosomal enhancer maps in multiple brain regions related to autism spectrum disorder
Lu Zhang,Li Liu,Yan Wen,Mei Ma,Shiqiang Cheng,Jian Yang,Ping Li,Bolun Cheng,Yanan Du,Xiao Liang,Yan Zhao,Miao Ding,Xiong Guo,Feng Zhang +13 more
TL;DR: An integrative analysis of genome‐wide association study (GWAS) and brain region related enhancer‐gene networks for ASD and several cross brain regions pathways were detected, providing novel clues for understanding the genetic basis of ASD.
Journal ArticleDOI
A TOR2A Gene Product: Salusin-β Contributes to Attenuated Vasodilatation of Spontaneously Hypertensive Rats
TL;DR: Results indicated that enhanced salusin-β activity is involved in attenuated endothelium-dependent vasodilatation pathogenesis in SHR by activating NAD(P)H oxidase derived ROS generation and inhibiting eNOS activation and NO release.
Journal ArticleDOI
CFAP65 is required in the acrosome biogenesis and mitochondrial sheath assembly during spermiogenesis.
Weili Wang,Shixong Tian,Hongchuan Nie,Chaofeng Tu,Chunyu Liu,Yong Li,Dongyan Li,Xiaoxuan Yang,Lanlan Meng,Tong-Yao Hu,Qianjun Zhang,Juan Du,Liqing Fan,Guangxiu Lu,Ge Lin,Feng Zhang,Yue-Qiu Tan +16 more
TL;DR: In this paper, the role of CFAP65 during spermiogenesis using Cfap65 knockout (Cfap65-/-) mice was examined, and it was shown that CFAP-affected male mice exhibited severe asthenoteratospermia characterized by morphologically defective sperm heads and flagella.
Hypoxia as a therapy for mitochondrial disease
Isha H. Jain,Luca Zazzeron,Rahul Goli,Rahul Goli,Kristen Alexa,Stephanie Schatzman-Bone,Harveen Dhillon,Harveen Dhillon,Olga Goldberger,Olga Goldberger,Jun Peng,Jun Peng,Ophir Shalem,Neville E. Sanjana,Neville E. Sanjana,Neville E. Sanjana,Feng Zhang,Feng Zhang,Feng Zhang,Wolfram Goessling,Warren M. Zapol,Vamsi K. Mootha,Vamsi K. Mootha +22 more
TL;DR: In this paper, the authors performed a genome-wide Cas9-mediated screen to identify factors that are protective during RC inhibition, highlighting the hypoxia response, an endogenous program evolved to adapt to limited oxygen availability.