F
Frank B. Hu
Researcher at Harvard University
Publications - 1784
Citations - 295051
Frank B. Hu is an academic researcher from Harvard University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 250, co-authored 1675 publications receiving 253464 citations. Previous affiliations of Frank B. Hu include Southwest University & Brigham and Women's Hospital.
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Journal ArticleDOI
Potential Impact of Time Trend of Life-Style Factors on Cardiovascular Disease Burden in China
Yanping Li,Dong D. Wang,Sylvia H. Ley,Annie Green Howard,Yuna He,Yuan Lu,Goodarz Danaei,Frank B. Hu +7 more
TL;DR: High blood pressure remains the most important individual risk factor related to CVD burden in China, and high rates of tobacco use in men and unhealthy dietary factors continue to contribute to the burden of CVD in China.
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Type 2 diabetes mellitus and 20 year incidence of periodontitis and tooth loss
TL;DR: Type 2 diabetes mellitus was associated with a significantly greater risk of self-reported periodontitis and tooth loss than previously thought.
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Genome-wide association Scan of dental caries in the permanent dentition
Xiao Jing Wang,John R. Shaffer,Zhen Zeng,Ferdouse Begum,Alexandre R. Vieira,Jacqueline Noel,Ida Anjomshoaa,Karen T. Cuenco,Myoung Keun Lee,James D. Beck,Eric Boerwinkle,Marilyn C. Cornelis,Frank B. Hu,David R. Crosslin,Cathy C. Laurie,Sarah C. Nelson,Kimberly F. Doheny,Elizabeth W. Pugh,Deborah E. Polk,Robert J. Weyant,Richard J. Crout,Daniel W. McNeil,Daniel E. Weeks,Eleanor Feingold,Mary L. Marazita +24 more
TL;DR: As the first genome-wide association study (GWAS) for dental caries in adults, this study nominated several novel caries genes for future study, which may lead to better understanding of cariogenesis, and ultimately, to improved disease predictions, prevention, and/or treatment.
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Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Alexander Teumer,Qibin Qi,Maria Nethander,Hugues Aschard,Stefania Bandinelli,Marian Beekman,Sonja I. Berndt,Martin Bidlingmaier,Linda Broer,Anne R. Cappola,Gian Paolo Ceda,Stephen Chanock,Ming-Huei Chen,Tai C. Chen,Yii-Der Ida Chen,Jonathan H. Chung,Fabiola Del Greco Miglianico,Joel Eriksson,Luigi Ferrucci,Nele Friedrich,Carsten Gnewuch,Mark O. Goodarzi,Niels Grarup,Tingwei Guo,Elke Hammer,Richard B. Hayes,Andrew A. Hicks,Albert Hofman,Jeanine J. Houwing-Duistermaat,Frank B. Hu,David J. Hunter,Lise Lotte N. Husemoen,Aaron Isaacs,Kevin B. Jacobs,Joop A M J L Janssen,John-Olov Jansson,Nico Jehmlich,Simon C. Johnson,Anders Juul,Magnus Karlsson,Tuomas O. Kilpeläinen,Peter Kovacs,Peter Kraft,Chao Li,Allan Linneberg,Yongmei Liu,Ruth J. F. Loos,Mattias Lorentzon,Yingchang Lu,M. Maggio,Reedik Mägi,James B. Meigs,Dan Mellström,Matthias Nauck,Anne B. Newman,Michael Pollak,Peter P. Pramstaller,Inga Prokopenko,Bruce M. Psaty,Martin Reincke,Eric B. Rimm,Jerome I. Rotter,Aude Saint Pierre,Aude Saint Pierre,Claudia Schurmann,Sudha Seshadri,Klara Sjögren,P. Eline Slagboom,Howard D. Strickler,Michael Stumvoll,Yousin Suh,Qi Sun,Cuilin Zhang,Cuilin Zhang,Johan Svensson,Toshiko Tanaka,Archana Tare,A Tönjes,Hae-Won Uh,Cornelia M. van Duijn,Diana van Heemst,Liesbeth Vandenput,Ramachandran S. Vasan,Uwe Völker,Sara M. Willems,Claes Ohlsson,Henri Wallaschofski,Robert C. Kaplan +87 more
TL;DR: This study identified several loci associated with circulating IGF‐I and IGFBP‐3 concentrations and provides clues to the potential role of the IGF axis in mediating effects of known (FOXO3) and novel (ASXL2) longevity‐associated loci.
Journal ArticleDOI
Low birthweight and risk of type 2 diabetes: a Mendelian randomisation study.
Tiange Wang,Tiange Wang,Tiange Wang,Tao Huang,Tao Huang,Yanping Li,Yan Zheng,JoAnn E. Manson,JoAnn E. Manson,Frank B. Hu,Frank B. Hu,Lu Qi,Lu Qi,Lu Qi +13 more
TL;DR: The findings support a potential causal relation between birthweight and risk of type 2 diabetes, providing new evidence to support the role of intrauterine exposures in the pathogenesis ofType 2 diabetes.