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Gianluca Campanella
Researcher at Imperial College London
Publications - 32
Citations - 2331
Gianluca Campanella is an academic researcher from Imperial College London. The author has contributed to research in topics: DNA methylation & Lung cancer. The author has an hindex of 19, co-authored 31 publications receiving 1908 citations. Previous affiliations of Gianluca Campanella include Paris Descartes University & Health Protection Agency.
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Journal ArticleDOI
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study.
John C. Chambers,Marie Loh,Marie Loh,Marie Loh,Benjamin Lehne,Alexander W. Drong,Jennifer Kriebel,Valeria Motta,Simone Wahl,Hannah R Elliott,Hannah R Elliott,Federica Rota,William R. Scott,William R. Scott,Weihua Zhang,Weihua Zhang,Sian-Tsung Tan,Sian-Tsung Tan,Gianluca Campanella,Marc Chadeau-Hyam,Loic Yengo,Loic Yengo,Rebecca C Richmond,Martyna Adamowicz-Brice,Uzma Afzal,Uzma Afzal,Kiymet Bozaoglu,Zuan Yu Mok,Hong Kiat Ng,François Pattou,François Pattou,Holger Prokisch,Michelle Ann Rozario,Letizia Tarantini,James Abbott,Mika Ala-Korpela,Benedetta Albetti,Ole Ammerpohl,Pier Alberto Bertazzi,Christine Blancher,R. Caiazzo,R. Caiazzo,John Danesh,Tom R. Gaunt,Simon de Lusignan,Christian Gieger,Thomas Illig,Sujeet Jha,Simon Jones,Jeremy B. M. Jowett,Antti J. Kangas,Anuradhani Kasturiratne,Norihiro Kato,Navaratnam Kotea,Sudhir Kowlessur,Janne Pitkäniemi,Prakash P Punjabi,Danish Saleheen,Danish Saleheen,Clemens Schafmayer,Pasi Soininen,Pasi Soininen,E-Shyong Tai,Barbara Thorand,Jaakko Tuomilehto,Ananda R. Wickremasinghe,Soterios A. Kyrtopoulos,Timothy J. Aitman,Christian Herder,Jochen Hampe,Stéphane Cauchi,Stéphane Cauchi,Caroline L Relton,Philippe Froguel,Richie Soong,Paolo Vineis,Marjo-Riitta Järvelin,James Scott,Harald Grallert,Valentina Bollati,Paul Elliott,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Jaspal S. Kooner +84 more
TL;DR: A nested case-control study of DNA methylation in Indian Asians and Europeans with incident type 2 diabetes who were identified from the 8-year follow-up of 25 372 participants in the London Life Sciences Prospective Population study.
Journal ArticleDOI
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Norihiro Kato,Marie Loh,Marie Loh,Marie Loh,Fumihiko Takeuchi,Niek Verweij,Xu Wang,Weihua Zhang,Tanika NKelly,Danish Saleheen,Danish Saleheen,Benjamin Lehne,Irene Mateo Leach,Alexander W. Drong,James Abbott,Simone Wahl,Sian Tsung Tan,William R. Scott,Gianluca Campanella,Marc Chadeau-Hyam,Uzma Afzal,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Marc Jan Bonder,Peng Chen,Abbas Dehghan,Todd L. Edwards,Tõnu Esko,Min Jin Go,Sarah E. Harris,Jaana Hartiala,Silva Kasela,Anuradhani Kasturiratne,Chiea Chuen Khor,Marcus E. Kleber,Huaixing Li,Zuan Yu Mok,Masahiro Nakatochi,Nur Sabrina Sapari,Richa Saxena,Alexandre F.R. Stewart,Lisette Stolk,Yasuharu Tabara,Ai Ling Teh,Ying Wu,Jer-Yuarn Wu,Yi Zhang,Imke Aits,Alexessander Couto Alves,Shikta Das,Rajkumar Dorajoo,Jemma CHopewell,Yun Kyoung Kim,Robert WKoivula,Jian'an Luan,Leo-Pekka Lyytikäinen,Quang NNguyen,Mark A. Pereira,Iris Postmus,Olli TRaitakari,Molly Scannell Bryan,Robert A. Scott,Rossella Sorice,Vinicius Tragante,Michela Traglia,Jon White,Ken Yamamoto,Yonghong Zhang,Linda S. Adair,Alauddin Ahmed,Koichi Akiyama,Rasheed Asif,Tin Aung,Inês Barroso,Andrew Bjonnes,Timothy R. Braun,Hui Cai,Li Ching Chang,Chien Hsiun Chen,Ching-Yu Cheng,Yap Seng Chong,Yap Seng Chong,Rory Collins,Regina Courtney,Gail Davies,Graciela E. Delgado,Loi D. Do,Pieter A. Doevendans,Ron T. Gansevoort,Yu-Tang Gao,Tanja B. Grammer,Niels Grarup,Jagvir Grewal,Dongfeng Gu,Gurpreet SWander,Anna-Liisa Hartikainen,Stanley L. Hazen,Jing He,Chew-Kiat Heng,E. James Ames Hixso,Albert Hofman,Chris Hsu,Wei Huang,Lise Lotte N. Husemoen,Joo Yeon Hwang,Sahoko Ichihara,Michiya Igase,Masato Isono,Johanne Marie Justesen,Tomohiro Katsuya,Muhammad GKibriya,Young Jin Kim,Miyako Kishimoto,Woon-Puay Koh,Katsuhiko Kohara,Meena Kumari,Kenneth Kwek,Nanette R. Lee,Jeannette Lee,Jiemin Liao,Jiemin Liao,Wolfgang Lieb,David C. Liewald,Tatsuaki Matsubara,Yumi Matsushita,Thomas Meitinger,Evelin Mihailov,Lili Milani,Rebecca Mills,Nina Mononen,Martina Müller-Nurasyid,Toru Nabika,Eitaro Nakashima,Hong Kiat Ng,Kjell Nikus,Teresa Nutile,Takayoshi Ohkubo,Keizo Ohnaka,Sarah Parish,Lavinia Paternoster,Hao Peng,Annette Peters,Son TPham,M.J. Pinidiyapathirage,Mahfuzar Rahman,Hiromi Rakugi,Olov Rolandsson,Michelle Ann Rozario,Daniela Ruggiero,Cinzia Sala,Ralhan Sarju,Kazuro Shimokawa,Harold Snieder,Thomas Sparsø,Wilko Spiering,John M. Starr,David J. Stott,Daniel OStram,Takao Sugiyama,Silke Szymczak,W.H. Wilson Tang,Lin Tong,Stella Trompet,Väinö Turjanmaa,Hirotsugu Ueshima,André G. Uitterlinden,Satoshi Umemura,Marja Vääräsmäki,Rob M. van Dam,Wiek H. van Gilst,Dirk J. van Veldhuisen,Jorma Viikari,Melanie Waldenberger,Yiqin Wang,Aili Wang,Rory P. Wilson,Tien Yin Wong,Tien Yin Wong,Yong-Bing Xiang,Shuhei Yamaguchi,Xingwang Ye,Robin Young,Terri L. Young,Jian-Min Yuan,Xueya Zhou,Folkert W. Asselbergs,Folkert W. Asselbergs,Marina Ciullo,Robert Clarke,Panos Deloukas,Panos Deloukas,Andre Franke,W. Frank Paul,Steve Franks,Yechiel Friedlander,Myron D. Gross,Zhirong Guo,Torben Hansen,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Torben Jørgensen,J. Wouter Jukema,Mika Kähönen,Hiroshi Kajio,Mika Kivimäki,Jong-Young Lee,Terho Lehtimäki,Allan Linneberg,Tetsuro Miki,Oluf Pedersen,Nilesh J. Samani,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Ryoichi Takayanagi,Daniela Toniolo,Habibul Ahsan,Hooman Allayee,Yuan-Tsong Chen,John Danesh,John Danesh,Ian J. Deary,Oscar H. Franco,Lude Franke,Bastiaan THeijman,Joanna D. Holbrook,Aaron Isaacs,Bong Jo Kim,Xu Lin,Jianjun Liu,Winfried März,Andres Metspalu,Karen L. Mohlke,K. Sangher,Dharambir Harambir,Xiao-Ou Shu,Joyce B. J. van Meurs,Eranga N. Vithana,Ananda R. Wickremasinghe,Cisca Wijmenga,Bruce H W Wolffenbuttel,Mitsuhiro Yokota,Wei Zheng,Dingliang Zhu,Paolo Vineis,Soterios A. Kyrtopoulos,Jos C. S. Kleinjans,Mark I. McCarthy,Richie Soong,Christian Gieger,James Scott,Yik Ying Teo,Jiang He,Paul Elliott,E. Shyong Tai,Pim van der Harst,Jaspal S. Kooner,John C. Chambers +256 more
TL;DR: The trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry finds genetic variants at 12 new loci to be associated with blood pressure, providing new evidence for the role of DNA methylation in blood pressure regulation.
Journal ArticleDOI
Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation
Florence Guida,Torkjel M. Sandanger,Raphaële Castagné,Gianluca Campanella,Silvia Polidoro,Domenico Palli,Vittorio Krogh,Rosario Tumino,Carlotta Sacerdote,Salvatore Panico,Gianluca Severi,Gianluca Severi,Soterios A. Kyrtopoulos,Panagiotis Georgiadis,Roel Vermeulen,Roel Vermeulen,Eiliv Lund,Paolo Vineis,Marc Chadeau-Hyam,Marc Chadeau-Hyam +19 more
TL;DR: This study highlights persistent epigenetic markers of smoking, which can potentially be detected decades after cessation, and are promising biomarkers to refine individual risk profiling of smoking-induced chronic disease such as lung cancer.
Journal ArticleDOI
Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts
Francesca Fasanelli,Laura Baglietto,Erica Ponzi,Florence Guida,Gianluca Campanella,Mattias Johansson,Mattias Johansson,Kjell Grankvist,Mikael Johansson,Manuela Bianca Assumma,Alessio Naccarati,Marc Chadeau-Hyam,Ugo Ala,Christian Faltus,Rudolf Kaaks,Angela Risch,Angela Risch,Bianca De Stavola,Allison M. Hodge,Graham G. Giles,Graham G. Giles,Melissa C. Southey,Caroline L Relton,Philip C Haycock,Eiliv Lund,Silvia Polidoro,Torkjel M. Sandanger,Gianluca Severi,Paolo Vineis +28 more
TL;DR: The most significant associations with lung cancer risk are for cg05575921 in AHRR (OR for 1 s.d.=0.37, 95% CI: 0.31-0.54, P-value=3.9 × 10(-10)), previously shown to be strongly hypomethylated in smokers as mentioned in this paper.
Journal ArticleDOI
R2GUESS: A Graphics Processing Unit-Based R Package for Bayesian Variable Selection Regression of Multivariate Responses.
TL;DR: R2GUESS, an R package wrapping the original C++ source code, is proposed, providing a user-friendly interface of the original code automating its parametrisation, and data handling, which incorporates many features to explore the data, and extend statistical inferences from the native algorithm.