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Hong Liu

Researcher at Shandong University

Publications -  2349
Citations -  79103

Hong Liu is an academic researcher from Shandong University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 100, co-authored 1905 publications receiving 57561 citations. Previous affiliations of Hong Liu include Shanghai University & Guangzhou University.

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Structure-Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists.

TL;DR: Compound 34 exhibited no CYP450-inhibition activity at 25 μM, which overcomes the potential drug-drug interaction of maraviroc, and represents a promising drug candidate for HIV-infection treatment.
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Construction of a biotinylated cameloid-like antibody for lable-free detection of apolipoprotein B-100

TL;DR: This proposed immunosensor revealed high specificity to detect ApoB-100, acceptable intra-assay precision and good stability, functioning as a feasible technique for CAD diagnosis.
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Benzamide derivatives as dual-action hypoglycemic agents that inhibit glycogen phosphorylase and activate glucokinase.

TL;DR: A series of benzamide derivatives which can simultaneously inhibit glycogen phosphorylase (GP) and activate glucokinase (GK) were prepared and evaluated and the structure-activity relationships (SAR) of these compounds were presented.
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Identification of novel thiadiazoloacrylamide analogues as inhibitors of dengue-2 virus NS2B/NS3 protease.

TL;DR: A novel class of thiadiazoloacrylamide derivatives with potent inhibitory activity against the NS2B/NS3 protease is reported, in which the nitrile group in the linker part was discovered as an essential group for the inhibitory activities.