Hong Liu

TL;DR: It is demonstrated that structure-based computer screening strategy could be used to identify novel, structurally diverse compounds targeting the pore binding pocket of the outer mouth of voltage-gated K+ channels.

TL;DR: In this paper, a near-stoichiometric LiNbO 3 (N-SLN) single crystal of 40mm in diameter and 60mm in length has been grown by Czochralski method from a 58.5% Li melt in a platinum crucible.

TL;DR: In this paper, the authors showed that although inhibition of xCT either by pharmacological inhibitor (sulfasalazine [SAS]), approved by US Food and Drug Administration (FDA) for inflammatory diseases, or genetic knockdown induced reactive oxygen species (ROS)-related death in melanoma cells significantly reduced the efficacy of anti-PD-1/PD-L1 immune checkpoint blockade through upregulating PD-L 1 expression via the transcription factors IRF4/EGR1, as a consequence, exosomes carrying relatively large amounts of PD-l

TL;DR: A novel reduced graphene oxide supported nickel cobaltate nanorods composite (RGO-NiCo2O4) was prepared by a simple ionothermal method in deep eutectic solvents for the first time and exhibited excellent electrocatalytic performance towards the oxidation of glucose.

TL;DR: It is suggested that Art could provide renoprotective role by attenuating the tubulointerstitial inflammation and fibrosis in SNx rats by downregulating the NF‐κB/NLRP3 signaling pathway.