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Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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Journal ArticleDOI
Bacterial and Chemical Evidence of Coastal Water Pollution from the Tijuana River in Sea Spray Aerosol
Matthew A. Pendergraft,Pedro Belda-Ferre,Daniel Petras,Clare K. Morris,Brock A. Mitts,Allegra T. Aron,M. Bryant,Tara Schwartz,Gail Ackermann,Gregory Humphrey,Ethan Kaandorp,Pieter C. Dorrestein,Rob Knight,Kimberly A. Prather +13 more
TL;DR: In this article , 16S rRNA gene amplicon sequencing was used to detect sewage-associated bacteria in the polluted Tijuana River flowing into coastal waters and returning to land in marine aerosol.
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Utilizing stability criteria in choosing feature selection methods yields reproducible results in microbiome data.
Lingjing Jiang,Niina Haiminen,Anna Paola Carrieri,Shi Huang,Yoshiki Vázquez-Baeza,Laxmi Parida,Ho-Cheol Kim,Austin D. Swafford,Rob Knight,Loki Natarajan +9 more
TL;DR: In this article, the authors compare the performance of popular model prediction metrics (MSE or AUC) with proposed reproducibility criterion Stability in evaluating four widely used feature selection methods in both simulations and experimental microbiome applications with continuous or binary outcomes.
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Reply to Sun et al., "Identifying Composition Novelty in Microbiome Studies: Improvement of Prediction Accuracy".
Xiaoquan Su,Gongchao Jing,Daniel McDonald,Hong-Lei Wang,Zengbin Wang,Antonio Gonzalez,Zheng Sun,Shi Huang,Jose Navas,Rob Knight,Jian Xu +10 more
TL;DR: To quantitatively measure the beta diversities between microbiomes, Microbiome Search Engine (MSE) calculates phylogeny similarity using operational taxonomy unit (OTU) profiles and the speed is optimized by nonrecursive computing to enable real-time responses.
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Conceptualizing a Genomics Software Institute (GSI)
Jack A. Gilbert,Jack A. Gilbert,Charlie Catlett,Charlie Catlett,Narayan Desai,Narayan Desai,Rob Knight,Rob Knight,Owen White,Robert K. Robbins,Rajesh Sankaran,Rajesh Sankaran,Susanna-Assunta Sansone,Dawn Field,Dawn Field,Folker Meyer,Folker Meyer +16 more
TL;DR: The need for focused community interaction to augment and deepen established community efforts, beginning with the Genomic Standards Consortium (GSC), is discussed, to create a science-driven strategic plan for a Genomic Software Institute (GSI).
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The Gut Microbial Bile Acid Modulation and Its Relevance to Digestive Health and Diseases
TL;DR: The human gut microbiome has been linked to numerous digestive disorders, but its metabolic products have been much less well characterized, in part due to the expense of untargeted metabolomics and lack of ability to process the data as discussed by the authors .