R
Robert S. Fulton
Researcher at Washington University in St. Louis
Publications - 254
Citations - 167513
Robert S. Fulton is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 109, co-authored 230 publications receiving 143530 citations. Previous affiliations of Robert S. Fulton include University of Washington & Brown University.
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Journal ArticleDOI
Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas
Adam Abeshouse,Clement Adebamowo,Sally N. Adebamowo,Rehan Akbani,Teniola Akeredolu,Adrian Ally,Matthew L. Anderson,Pavana Anur,Elizabeth L. Appelbaum,Joshua Armenia,J. Todd Auman,Matthew A. Bailey,Laurence H. Baker,Miruna Balasundaram,Saianand Balu,Floris P. Barthel,John Bartlett,Stephen B. Baylin,Madhusmita Behera,Dmitry Belyaev,Joesph Bennett,Christopher C. Benz,Rameen Beroukhim,Michael J. Birrer,Therese Bocklage,Tom Bodenheimer,Lori Boice,Moiz S. Bootwalla,Jay Bowen,Reanne Bowlby,Jeff Boyd,Andrew S. Brohl,Denise Brooks,Lauren Averett Byers,Rebecca Carlsen,Patricia Castro,Hsiao-Wei Chen,Andrew D. Cherniack,Frédéric Chibon,Lynda Chin,Juok Cho,Eric Chuah,Sudha Chudamani,Carrie Cibulskis,Lee Cooper,Leslie Cope,Matthew G. Cordes,Daniel Crain,Erin Curley,Ludmila Danilova,Fanny Dao,Ian J. Davis,Lara E. Davis,Timothy Defreitas,Keith A. Delman,John A. Demchok,George D. Demetri,Elizabeth G. Demicco,Noreen Dhalla,Lixia Diao,Li Ding,Phil DiSaia,Peter Dottino,Leona A. Doyle,Esther Drill,Michael Dubina,Jennifer M. Eschbacher,Konstantin V. Fedosenko,Ina Felau,Martin L. Ferguson,Scott Frazer,Catrina Fronick,Victoria Fulidou,Lucinda Fulton,Robert S. Fulton,Stacey Gabriel,Jianjiong Gao,Qingsong Gao,Johanna Gardner,Julie M. Gastier-Foster,Nils Gehlenborg,Mark Gerken,Gad Getz,Andrew K. Godwin,Eryn M. Godwin,Elena Gordienko,Juneko E. Grilley-Olson,David A. Gutman,David H. Gutmann,D. Neil Hayes,Apurva M. Hegde,David I. Heiman,Zachary J. Heins,Carmen Helsel,Austin J. Hepperla,Kelly Higgins,Katherine A. Hoadley,Shital Hobensack,Robert A. Holt,Dave B. Hoon,Jason L. Hornick,Alan P. Hoyle,Xin Hu,Mei Huang,Carolyn M. Hutter,Mary Iacocca,Davis R. Ingram,Michael Ittmann,Lisa Iype,Stuart R. Jefferys,Kevin B. Jones,Corbin D. Jones,Steven J.M. Jones,Tamara Kalir,Beth Y. Karlan,Apollon Karseladze,Katayoon Kasaian,Jaegil Kim,Ritika Kundra,Hanluen Kuo,Marc Ladanyi,Phillip H. Lai,Peter W. Laird,Erik G. Larsson,Michael S. Lawrence,Alexander J. Lazar,Sanghoon Lee,Darlene Lee,Kjong-Van Lehmann,Kristen M. Leraas,Jenny Lester,Douglas A. Levine,Irene Li,Tara M. Lichtenberg,Pei Lin,Jia Liu,Wen-Bin Liu,Eric Minwei Liu,Laxmi Lolla,Yiling Lu,Yussanne Ma,Rashna Madan,Dennis T. Maglinte,Anthony M. Magliocco,Robert G. Maki,David Mallery,Georgy Manikhas,Elaine R. Mardis,Armaz Mariamidze,Marco A. Marra,John A. Martignetti,Cathleen Martinez,Michael Mayo,Michael D. McLellan,Sam Meier,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,Christopher A. Miller,Gordon B. Mills,Richard A. Moore,Scott Morris,Lisle E. Mose,Evgeny Mozgovoy,Andrew J. Mungall,Karen Mungall,Michael Nalisnik,Rashi Naresh,Yulia Newton,Michael S. Noble,Janet E. Novak,Angelica Ochoa,Narciso Olvera,Taofeek K. Owonikoko,Oxana Paklina,Jeremy Parfitt,Joel S. Parker,Alessandro Pastore,Joseph Paulauskis,Robert Penny,Elena Pereira,Charles M. Perou,Amy H. Perou,Todd Pihl,Raphael E. Pollock,Olga Potapova,Amie Radenbaugh,Suresh S. Ramalingam,Nilsa C. Ramirez,W. Kimryn Rathmell,Chandrajit P. Raut,Richard F. Riedel,Colleen Reilly,Sheila Reynolds,Jeffrey Roach,A. Gordon Robertson,Jason Roszik,Brian P. Rubin,Sara Sadeghi,Gordon Saksena,Andrew Salner,Francisco Sanchez-Vega,Chris Sander,Jacqueline E. Schein,Heather Schmidt,Nikolaus Schultz,Steven E. Schumacher,Harman Sekhon,Yasin Senbabaoglu,Galiya Setdikova,Candace Shelton,Troy Shelton,Ronglai Shen,Yan Shi,Juliann Shih,Ilya Shmulevich,Gabriel Sica,Janae V. Simons,Samuel Singer,Payal Sipahimalani,Tara Skelly,Nicholas D. Socci,Heidi J. Sofia,Matthew G. Soloway,Paul T. Spellman,Qiang Sun,Patricia Swanson,Angela Tam,Donghui Tan,Roy Tarnuzzer,Nina Thiessen,Eric M. Thompson,Leigh B. Thorne,Pan Tong,Keila E. Torres,Matt van de Rijn,David Van Den Berg,Brian A. Van Tine,Umadevi Veluvolu,Roel G.W. Verhaak,Doug Voet,Olga Voronina,Yunhu Wan,Zhining Wang,Jing Wang,John N. Weinstein,Daniel J. Weisenberger,Matthew D. Wilkerson,Richard K. Wilson,Lisa Wise,Tina Wong,Wing Hing Wong,John Wrangle,Ye Wu,Matthew A. Wyczalkowski,Liming Yang,Christina Yau,Venkata Yellapantula,Jean C. Zenklusen,Jiashan Zhang,Hailei Zhang,Hongxin Zhang,Erik Zmuda +262 more
TL;DR: This large-scale analysis of 206 adult soft tissue sarcomas reveals previously unappreciated sarcoma-type-specific changes in copy number, methylation, RNA, and protein, providing insights into refining Sarcoma therapy and relationships to other cancer types.
Journal ArticleDOI
Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
Michael A. Mahowald,Federico E. Rey,Henning Seedorf,Peter J. Turnbaugh,Robert S. Fulton,Aye Wollam,Neha Shah,Chunyan Wang,Vincent Magrini,Richard K. Wilson,Brandi L. Cantarel,Brandi L. Cantarel,Pedro M. Coutinho,Bernard Henrissat,Bernard Henrissat,Lara W. Crock,Alison L Russell,Nathan C Verberkmoes,Robert L. Hettich,Jeffrey I. Gordon +19 more
TL;DR: A simplified model of the human gut microbiota illustrates niche specialization and functional redundancy within members of its major bacterial phyla, and the importance of host glycans as a nutrient foundation that ensures ecosystem stability.
Journal ArticleDOI
Genomic and Functional Approaches to Understanding Cancer Aneuploidy
Alison M. Taylor,Alison M. Taylor,Juliann Shih,Gavin Ha,Gavin Ha,Galen F. Gao,Xiaoyang Zhang,Xiaoyang Zhang,Ashton C. Berger,Steven E. Schumacher,Steven E. Schumacher,Chen Wang,Hai Hu,Jianfang Liu,Alexander J. Lazar,Samantha J. Caesar-Johnson,John A. Demchok,Ina Felau,Melpomeni Kasapi,Martin L. Ferguson,Carolyn M. Hutter,Heidi J. Sofia,Roy Tarnuzzer,Zhining Wang,Liming Yang,Jean C. Zenklusen,Jiashan Zhang,Sudha Chudamani,Jia Liu,Laxmi Lolla,Rashi Naresh,Todd Pihl,Qiang Sun,Yunhu Wan,Ye Wu,Juok Cho,Timothy Defreitas,Scott Frazer,Nils Gehlenborg,Gad Getz,David I. Heiman,Jaegil Kim,Michael S. Lawrence,Pei Lin,Sam Meier,Michael S. Noble,Gordon Saksena,Doug Voet,Hailei Zhang,Brady Bernard,Nyasha Chambwe,Varsha Dhankani,Theo A. Knijnenburg,Roger Kramer,Kalle Leinonen,Yuexin Liu,Michael W. Miller,Sheila Reynolds,Ilya Shmulevich,Vesteinn Thorsson,Wei Zhang,Rehan Akbani,Bradley M. Broom,Apurva M. Hegde,Zhenlin Ju,Rupa S. Kanchi,Anil Korkut,Jun Li,Han Liang,Shiyun Ling,Wen-Bin Liu,Yiling Lu,Gordon B. Mills,Kwok Shing Ng,Arvind Rao,Michael T. Ryan,Jing Wang,John N. Weinstein,Jiexin Zhang,Adam Abeshouse,Joshua Armenia,Debyani Chakravarty,Walid K. Chatila,Ino de Bruijn,Jianjiong Gao,Benjamin Gross,Zachary J. Heins,Ritika Kundra,Konnor La,Marc Ladanyi,Augustin Luna,Moriah G. Nissan,Angelica Ochoa,Sarah Phillips,Ed Reznik,Francisco Sanchez-Vega,Chris Sander,Nikolaus Schultz,Robert L. Sheridan,S. Onur Sumer,Yichao Sun,Barry S. Taylor,Jioajiao Wang,Hongxin Zhang,Pavana Anur,Myron Peto,Paul T. Spellman,Christopher C. Benz,Joshua M. Stuart,Christopher K. Wong,Christina Yau,D. Neil Hayes,Joel S. Parker,Matthew D. Wilkerson,Adrian Ally,Miruna Balasundaram,Reanne Bowlby,Denise Brooks,Rebecca Carlsen,Eric Chuah,Noreen Dhalla,Robert A. Holt,Steven J.M. Jones,Katayoon Kasaian,Darlene Lee,Yussanne Ma,Marco A. Marra,Michael Mayo,Richard A. Moore,Andrew J. Mungall,Karen Mungall,A. Gordon Robertson,Sara Sadeghi,Jacqueline E. Schein,Payal Sipahimalani,Angela Tam,Nina Thiessen,Kane Tse,Tina Wong,Rameen Beroukhim,Andrew D. Cherniack,Carrie Cibulskis,Stacey Gabriel,Matthew Meyerson,Melanie H. Kucherlapati,Raju Kucherlapati,Stephen B. Baylin,Leslie Cope,Ludmila Danilova,Moiz S. Bootwalla,Phillip H. Lai,Dennis T. Maglinte,David Van Den Berg,Daniel J. Weisenberger,J. Todd Auman,Saianand Balu,Tom Bodenheimer,Cheng Fan,Katherine A. Hoadley,Alan P. Hoyle,Stuart R. Jefferys,Corbin D. Jones,Shaowu Meng,Piotr A. Mieczkowski,Lisle E. Mose,Amy H. Perou,Charles M. Perou,Jeffrey Roach,Yan Shi,Janae V. Simons,Tara Skelly,Matthew G. Soloway,Donghui Tan,Umadevi Veluvolu,Huihui Fan,Toshinori Hinoue,Peter W. Laird,Hui Shen,Wanding Zhou,Michelle Bellair,Kyle Chang,Kyle R. Covington,Chad J. Creighton,Huyen Dinh,Harshavardhan Doddapaneni,Lawrence A. Donehower,Jennifer Drummond,Richard A. Gibbs,Robert Glenn,Walker Hale,Yi Han,Jianhong Hu,Viktoriya Korchina,Sandra J. Lee,Lora Lewis,Wei Li,Xiuping Liu,Margaret Morgan,Donna Morton,Donna M. Muzny,Jireh Santibanez,Margi Sheth,Eve Shinbrot,Linghua Wang,Min Wang,David A. Wheeler,Liu Xi,Fengmei Zhao,Julian M. Hess,Elizabeth L. Appelbaum,Matthew A. Bailey,Matthew G. Cordes,Li Ding,Catrina Fronick,Lucinda Fulton,Robert S. Fulton,Cyriac Kandoth,Elaine R. Mardis,Michael D. McLellan,Christopher A. Miller,Heather Schmidt,Rick K. Wilson,Daniel Crain,Erin Curley,Johanna Gardner,Kevin Lau,David Mallery,Scott Morris,Joseph Paulauskis,Robert Penny,Candace Shelton,Troy Shelton,Mark E. Sherman,Eric M. Thompson,Peggy Yena,Jay Bowen,Julie M. Gastier-Foster,Mark Gerken,Kristen M. Leraas,Tara M. Lichtenberg,Nilsa C. Ramirez,Lisa Wise,Erik Zmuda,Niall M. Corcoran,Tony Costello,Christopher M. Hovens,André Lopes Carvalho,Ana Carolina de Carvalho,José Humberto Tavares Guerreiro Fregnani,Adhemar Longatto-Filho,Rui Manuel Reis,Cristovam Scapulatempo-Neto,Henrique César Santejo Silveira,Daniel Onofre Vidal,Andrew Burnette,Jennifer M. Eschbacher,Beth Hermes,Ardene Noss,Rosy Singh,Matthew L. Anderson,Patricia Castro,Michael Ittmann,David G. Huntsman,Bernard Kohl,Xuan Le,Richard Thorp,Chris Andry,Elizabeth R. Duffy,Vladimir Lyadov,Oxana Paklina,Galiya Setdikova,Alexey Shabunin,Mikhail Tavobilov,Christopher M. McPherson,Ronald E. Warnick,Ross S. Berkowitz,Daniel W. Cramer,Colleen M. Feltmate,Neil S. Horowitz,Adam S. Kibel,Michael G. Muto,Chandrajit P. Raut,Andrei Malykh,Jill S. Barnholtz-Sloan,Wendi Barrett,Karen Devine,Jordonna Fulop,Quinn T. Ostrom,Kristen Shimmel,Yingli Wolinsky,Andrew E. Sloan,Agostino Maria De Rose,Felice Giuliante,Marc T. Goodman,Beth Y. Karlan,Curt H. Hagedorn,John Eckman,Jodi Harr,Jerome Myers,Kelinda Tucker,Leigh Anne Zach,Brenda Deyarmin,Leonid Kvecher,Caroline Larson,Richard J. Mural,Stella Somiari,Ales Vicha,Tomáš Zelinka,Joseph J. Bennett,Mary Iacocca,Brenda Rabeno,Patricia Swanson,Mathieu Latour,Louis Lacombe,Bernard Têtu,Alain Bergeron,Mary McGraw,Susan M. Staugaitis,John Chabot,Hanina Hibshoosh,Antonia R. Sepulveda,Tao Su,Timothy C. Wang,Olga Potapova,Olga Voronina,Laurence Desjardins,Odette Mariani,Sergio Roman-Roman,Xavier Sastre,Marc-Henri Stern,Feixiong Cheng,Sabina Signoretti,Andrew Berchuck,Darell D. Bigner,Eric S. Lipp,Jeffrey R. Marks,Shannon J. McCall,Roger E. McLendon,Angeles Alvarez Secord,Alexis Sharp,Madhusmita Behera,Daniel J. Brat,Amy Y. Chen,Keith A. Delman,Seth Force,Fadlo R. Khuri,Kelly R. Magliocca,Shishir K. Maithel,Jeffrey J. Olson,Taofeek K. Owonikoko,Alan Pickens,Suresh S. Ramalingam,Dong M. Shin,Gabriel Sica,Erwin G. Van Meir,Hongzheng Zhang,Wil Eijckenboom,Ad Gillis,Esther Korpershoek,Leendert H. J. Looijenga,Wolter Oosterhuis,Hans Stoop,Kim E.M. van Kessel,Ellen C. Zwarthoff,Chiara Calatozzolo,Lucia Cuppini,Stefania Cuzzubbo,Francesco DiMeco,Gaetano Finocchiaro,Luca Mattei,Alessandro Perin,Bianca Pollo,Chu Chen,John Houck,Pawadee Lohavanichbutr,Arndt Hartmann,Christine Stoehr,Robert Stoehr,Helge Taubert,Sven Wach,Bernd Wullich,Witold Kycler,Dawid Murawa,Maciej Wiznerowicz,Ki Chung,W. Jeffrey Edenfield,Julie S. Martin,Eric Baudin,Glenn J. Bubley,Raphael Bueno,Assunta De Rienzo,William G. Richards,Steven N. Kalkanis,Tom Mikkelsen,Houtan Noushmehr,Lisa Scarpace,Nicolas Girard,Marta Aymerich,Elias Campo,Eva Giné,Armando López Guillermo,Nguyen Van Bang,Phan Thi Hanh,Bui Duc Phu,Yufang Tang,Howard Colman,Kimberley Evason,Peter Dottino,John A. Martignetti,Hani Gabra,Hartmut Juhl,Teniola Akeredolu,Serghei Stepa,Dave S.B. Hoon,Keunsoo Ahn,Koo Jeong Kang,Felix Beuschlein,Anne Breggia,Michael J. Birrer,Debra A. Bell,Mitesh J. Borad,Alan H. Bryce,Erik P. Castle,Vishal S. Chandan,John C. Cheville,John A. Copland,Michael B. Farnell,Thomas J. Flotte,Nasra H. Giama,Thai H. Ho,Michael L. Kendrick,Jean Pierre A. Kocher,Karla Kopp,Catherine D. Moser,David M. Nagorney,Daniel R. O'Brien,Brian P. O'Neill,Tushar Patel,Gloria M. Petersen,Florencia G. Que,Michael Rivera,Lewis R. Roberts,Robert C. Smallridge,Thomas C. Smyrk,Melissa L. Stanton,R. Houston Thompson,Michael Torbenson,Ju Dong Yang,Lizhi Zhang,Fadi Brimo,Jaffer A. Ajani,Ana Maria Angulo Gonzalez,Carmen Behrens,Jolanta Bondaruk,Russell Broaddus,Bogdan Czerniak,Bita Esmaeli,Junya Fujimoto,Jeffrey E. Gershenwald,Charles C. Guo,Christopher J. Logothetis,Funda Meric-Bernstam,Cesar Moran,Lois M. Ramondetta,David C. Rice,Anil K. Sood,Pheroze Tamboli,Timothy C. Thompson,Patricia Troncoso,Anne Tsao,Ignacio I. Wistuba,Candace Carter,Lauren E. Haydu,Peter Hersey,Valerie Jakrot,Hojabr Kakavand,Richard F. Kefford,Kenneth K. Lee,Georgina V. Long,Graham J. Mann,Michael A. Quinn,Robyn P. M. Saw,Richard A. Scolyer,Kerwin F. Shannon,Andrew J. Spillane,Jonathan R. Stretch,Maria Synott,John F. Thompson,James S. Wilmott,Hikmat Al-Ahmadie,Timothy A. Chan,Ronald Ghossein,Anuradha Gopalan,Douglas A. Levine,Victor E. Reuter,Samuel Singer,Bhuvanesh Singh,Nguyen Viet Tien,Thomas Broudy,Cyrus Mirsaidi,Praveen Nair,Paul Drwiega,Judy Miller,Jennifer S. Smith,Howard Zaren,Joong-Won Park,Nguyen Phi Hung,Electron Kebebew,W. Marston Linehan,Adam R. Metwalli,Karel Pacak,Peter A. Pinto,Mark Schiffman,Laura S. Schmidt,Cathy D. Vocke,Nicolas Wentzensen,Robert Worrell,Hannah P. Yang,Marc Moncrieff,Chandra Goparaju,Jonathan Melamed,Harvey I. Pass,Natalia Botnariuc,Irina Caraman,Mircea Cernat,Inga Chemencedji,Adrian Clipca,Serghei Doruc,Ghenadie Gorincioi,Sergiu Mura,Maria Pirtac,Irina Stancul,Diana Tcaciuc,Monique Albert,Iakovina Alexopoulou,Angel Arnaout,John Bartlett,Jay Engel,Sebastien Gilbert,Jeremy Parfitt,Harman Sekhon,George Thomas,Doris M. Rassl,Robert C. Rintoul,Carlo Bifulco,Raina Tamakawa,Walter J. Urba,Nicholas K. Hayward,Henri J L M Timmers,Anna Antenucci,Francesco Facciolo,Gian Luca Grazi,Mirella Marino,Roberta Merola,Ronald R. de Krijger,Anne Paule Gimenez-Roqueplo,Alain Piché,Simone Chevalier,Ginette McKercher,Kıvanç Birsoy,Gene H. Barnett,Cathy Brewer,Carol Farver,Theresa Naska,Nathan A. Pennell,Daniel P. Raymond,Cathy Schilero,Kathy Smolenski,Felicia Williams,Carl Morrison,Jeffrey A. Borgia,Michael J. Liptay,Mark Pool,Christopher W. Seder,Kerstin Junker,Larsson Omberg,Mikhail Dinkin,George Manikhas,Domenico Alvaro,Maria Consiglia Bragazzi,Vincenzo Cardinale,Guido Carpino,Eugenio Gaudio,David Chesla,Sandra Cottingham,Michael Dubina,Fedor Moiseenko,Renumathy Dhanasekaran,Karl-Friedrich Becker,Klaus-Peter Janssen,Julia Slotta-Huspenina,Mohamed H. Abdel-Rahman,Dina Aziz,Sue E. Bell,Colleen M. Cebulla,Amy Davis,Rebecca Duell,J. Bradley Elder,Joe Hilty,Bahavna Kumar,James C. Lang,Norman L. Lehman,Randy Mandt,Phuong L. Nguyen,Robert Pilarski,Karan Rai,Lynn Schoenfield,Kelly Senecal,Paul Wakely,Paul Hansen,Ronald Lechan,James Powers,Arthur S. Tischler,William E. Grizzle,Katherine C. Sexton,Alison Kastl,Joel M. Henderson,Sima P. Porten,Jens Waldmann,Martin Fassnacht,Sylvia L. Asa,Dirk Schadendorf,Marta Couce,Markus Graefen,Hartwig Huland,Guido Sauter,Thorsten Schlomm,Ronald Simon,Pierre Tennstedt,Oluwole Olabode,Mark Nelson,Oliver F. Bathe,Peter R. Carroll,June M. Chan,Philip J. DiSaia,Pat Glenn,Robin Kate Kelley,Charles N. Landen,Joanna J. Phillips,Michael D. Prados,Jeffry Simko,Karen Smith-McCune,Scott R. VandenBerg,Kevin K. Roggin,Ashley Fehrenbach,Ady Kendler,Suzanne Sifri,Ruth Steele,Antonio Jimeno,Francis Carey,Ian Forgie,Massimo Mannelli,Michael E. Carney,Brenda Y. Hernandez,Benito Campos,Christel Herold-Mende,Christin Jungk,Andreas Unterberg,Andreas von Deimling,Aaron D. Bossler,Joseph Galbraith,Laura Jacobus,Michael Knudson,Tina Knutson,Deqin Ma,Mohammed M. Milhem,Rita Sigmund,Andrew K. Godwin,Rashna Madan,Howard G. Rosenthal,Clement Adebamowo,Sally N. Adebamowo,Alex Boussioutas,David G. Beer,Thomas P. Giordano,Anne Marie Mes-Masson,Fred Saad,Therese Bocklage,Lisa M. Landrum,Robert S. Mannel,Kathleen N. Moore,Katherine M. Moxley,Russel Postier,Joan L. Walker,Rosemary E. Zuna,Michael Feldman,Federico Valdivieso,Rajiv Dhir,James D. Luketich,Edna M. Mora Pinero,Mario Quintero-Aguilo,Carlos Gilberto Carlotti,Jose Sebastião Dos Santos,Rafael Kemp,Ajith Sankarankuty,Daniela Pretti da Cunha Tirapelli,James W.F. Catto,Kathy Agnew,Elizabeth M. Swisher,Jenette Creaney,Bruce W. S. Robinson,Carl Simon Shelley,Eryn M. Godwin,Sara Kendall,Cassaundra Shipman,Carol R. Bradford,Thomas E. Carey,Andrea Haddad,Jeffey Moyer,Lisa A. Peterson,Mark E. Prince,Laura S. Rozek,Gregory T. Wolf,Rayleen V. Bowman,Kwun M. Fong,Ian A. Yang,Robert Korst,W. Kimryn Rathmell,J. Leigh Fantacone-Campbell,Jeffrey A. Hooke,Albert J. Kovatich,Craig D. Shriver,John F. DiPersio,Bettina F. Drake,Ramaswamy Govindan,Sharon Heath,Timothy J. Ley,Brian A. Van Tine,Peter Westervelt,Mark A. Rubin,Jung Il Lee,Natália D. Aredes,Armaz Mariamidze +732 more
TL;DR: The genomic and phenotypic correlates of cancer aneuploidy are defined and genome engineering is applied to delete 3p in lung cells, causing decreased proliferation rescued in part by chromosome 3 duplication.
Journal ArticleDOI
A Catalog of Reference Genomes from the Human Microbiome
Karen E. Nelson,George M. Weinstock,Sarah K. Highlander,Kim C. Worley,Heather Huot Creasy,Jennifer R. Wortman,Douglas B. Rusch,Makedonka Mitreva,Erica Sodergren,Asif T. Chinwalla,Michael Feldgarden,Dirk Gevers,Brian J. Haas,Ramana Madupu,Doyle V. Ward,Bruce W. Birren,Richard A. Gibbs,Barbara A. Methé,Joseph F. Petrosino,Robert L. Strausberg,Granger G. Sutton,Owen White,Richard K. Wilson,Scott Durkin,Michelle G. Giglio,Sharvari Gujja,Clint Howarth,Chinnappa D. Kodira,Nikos C. Kyrpides,Teena Mehta,Donna M. Muzny,Matthew D. Pearson,Kymberlie H. Pepin,Amrita Pati,Xiang Qin,Chandri N. Yandava,Qiandong Zeng,Lan Zhang,Aaron M. Berlin,Lei Chen,Theresa A. Hepburn,Justin Johnson,Jamison McCorrison,Jason R. Miller,Patrick Minx,Chad Nusbaum,Carsten Russ,Sean M. Sykes,Chad Tomlinson,Sarah Young,Wesley C. Warren,Jonathan H. Badger,Jonathan Crabtree,Victor Markowitz,Joshua Orvis,Andrew Cree,Steve Ferriera,Lucinda Fulton,Robert S. Fulton,Marcus Gillis,Lisa Hemphill,Vandita Joshi,Christie Kovar,Manolito Torralba,Kris A. Wetterstrand,Amr Abouellleil,Aye Wollam,Christian J. Buhay,Yan Ding,Shannon Dugan,Michael Fitzgerald,Mike Holder,Jessica B. Hostetler,Sandra W. Clifton,Emma Allen-Vercoe,Ashlee M. Earl,Candace N. Farmer,Konstantinos Liolios,Michael G. Surette,Qiang Xu,Craig Pohl,Katarzyna Wilczek-Boney,Dianhui Zhu +82 more
TL;DR: Results from an initial reference genome sequencing of 178 microbial genomes allow for ~40% of random sequences from the microbiome of the gastrointestinal tract to be associated with organisms based on the match criteria used, suggesting that the authors are still far from saturating microbial species genetic data sets.
Journal ArticleDOI
TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes
John S. Welch,Allegra A. Petti,Christopher A. Miller,Catrina Fronick,Michelle O'Laughlin,Robert S. Fulton,Richard K. Wilson,Jack Baty,Eric J. Duncavage,Bevan Tandon,Yi-Shan Lee,Lukas D. Wartman,Geoffrey L. Uy,Armin Ghobadi,Michael H. Tomasson,Iskra Pusic,Rizwan Romee,Todd A. Fehniger,Keith Stockerl-Goldstein,Ravi Vij,Stephen T. Oh,Camille N. Abboud,Amanda F. Cashen,Mark A. Schroeder,Meagan A. Jacoby,Sharon Heath,Kierstin Luber,Megan Janke,Andrew Hantel,Niloufer Khan,Madina Sukhanova,Randall W. Knoebel,Wendy Stock,Timothy A. Graubert,Matthew J. Walter,Peter Westervelt,Daniel C. Link,John F. DiPersio,Timothy J. Ley +38 more
TL;DR: Patients with AML and MDS who had cytogenetic abnormalities associated with unfavorable risk, TP53 mutations, or both had favorable clinical responses and robust (but incomplete) mutation clearance after receiving serial 10-day courses of decitabine.