Commonwealth Scientific and Industrial Research Organisation

About: Commonwealth Scientific and Industrial Research Organisation is a government organization based out in Canberra, Australian Capital Territory, Australia. It is known for research contribution in the topics: Population & Soil water. The organization has 33765 authors who have published 79910 publications receiving 3356114 citations.

Living Radical Polymerization by the RAFT Process - A Second Update

Abstract: This paper provides a third update to the review of reversible deactivation radical polymerization (RDRP) achieved with thiocarbonylthio compounds (ZC(=S)SR) by a mechanism of reversible addition-fragmentation chain transfer (RAFT) that was published in June 2005 (Aust. J. Chem. 2005, 58, 379). The first update was published in November 2006 (Aust. J. Chem. 2006, 59, 669) and the second in December 2009 (Aust. J. Chem. 2009, 62, 1402). This review cites over 700 publications that appeared during the period mid 2009 to early 2012 covering various aspects of RAFT polymerization which include reagent synthesis and properties, kinetics and mechanism of polymerization, novel polymer syntheses, and a diverse range of applications. This period has witnessed further significant developments, particularly in the areas of novel RAFT agents, techniques for end-group transformation, the production of micro/nanoparticles and modified surfaces, and biopolymer conjugates both for therapeutic and diagnostic applications.

Spectropolarimetric observations of active stars

Abstract: This paper reports the results of five years (five runs, 23 nights) of spectropolarimetric observations of active stars with the UCL Echelle Spectrograph of the Anglo-Australian Telescope. 225 circularly (and four linearly) polarized spectra were recorded on 28 objects (21 active stars and seven calibration standards) using the new technique of Zeeman-Doppler imaging. To extract polarization echelle spectra from raw frames, we developed a new dedicated automatic software package (called ESpRIT, which utilizes optimal extraction techniques) whose detailed description is given in the paper. For each recorded spectrum, we extract 'mean' polarized and unpolarized profiles using 'least-squares deconvolution', a technique similar to cross-correlation, which can enhance enormously the sensitivity of Zeeman-Doppler imaging, by up to 7.5 mag in flux with respect to a single average line analysis or by 4.5 mag compared with the older technique of Donati et al. in the particular case of a K1 star. Magnetic field is detected unambiguously on 14 objects, namely the weak-line T Tauri star V410 Tau, the pre-main-sequence binary HD 155555, the ZAMS stars AB Dor and LQ Hya, the dwarf flare star CC Eri, the RS CVn systems HR 1099, EI Eri, TY Pyx, CF Tue, SZ Psc, II Peg, IM Peg and IL Hya, and the FK Com star YY Men. Marginal field detections are also obtained for the weak-line T Tauri star HD 283572 and the Herbig Ae star HD 104237. Except on HR 1099 and II Peg, our results represent the first direct field detections ever reported on these objects, and in particular the first direct field detection on as young a star as V410 Tau. Most of the magnetic signatures we detect on cool stars show several sign reversals throughout the line profile, indicating that the parent field structure is rather complex and must feature (as expected) many small-scale magnetic regions of different polarities. For all stars on which Zeeman detections are recorded with sufficient accuracy (namely LQ Hya, CC Eri, HR 1099, El Eri, II Peg, IL Hya and YY Men), differential least-squares deconvolution from both the blue and the red parts of the spectral domain indicates that the magnetic regions we detect are mostly 500 to 1000 K cooler than, and sometimes at the same temperature as, but never warmer than the surrounding photosphere. Serendipitous results include the first detection (i) of small-amplitude radial velocity variations (1.3 kms -1 peak to peak) of the Herbig Ae star HD 104237 with small enough a period (37.5 ± 1 min) that they must be due to stellar pulsations and (ii) of the solar-like secondary component of the RS CVn system IL Hya.

Biodegradable synthetic polymers for tissue engineering

Abstract: This paper reviews biodegradable synthetic polymers focusing on their potential in tissue engineering applications. The major classes of polymers are briefly discussed with regard to synthesis, properties and biodegradability, and known degradation modes and products are indicated based on studies reported in the literature. A vast majority of biodegradable polymers studied belongs to the polyester family, which includes polyglycolides and polylactides. Some disadvantages of these polymers in tissue engineering applications are their poor biocompatibility, release of acidic degradation products, poor processability and loss of mechanical properties very early during degradation. Other degradable polymers such as polyorthoesters, polyanhydrides, polyphosphazenes, and polyurethanes are also discussed and their advantages and disadvantages summarised. With advancements in tissue engineering it has become necessary to develop polymers that meet more demanding requirements. Recent work has focused on developing injectable polymer compositions based on poly (propylene fumarate) and poly (anhydrides) to meet these requirements in orthopaedic tissue engineering. Polyurethanes have received recent attention for development of degradable polymers because of their great potential in tailoring polymer structure to achieve mechanical properties and biodegradability to suit a variety of applications.

Conformations of immunoglobulin hypervariable regions.

Abstract: On the basis of comparative studies of known antibody structures and sequences it has been argued that there is a small repertoire of main-chain conformations for at least five of the six hypervariable regions of antibodies, and that the particular conformation adopted is determined by a few key conserved residues. These hypotheses are now supported by reasonably successful predictions of the structures of most hypervariable regions of various antibodies, as revealed by comparison with their subsequently determined structures.