University of Geneva

About: University of Geneva is a education organization based out in Geneva, Switzerland. It is known for research contribution in the topics: Population & Galaxy. The organization has 26887 authors who have published 65265 publications receiving 2931373 citations. The organization is also known as: Geneva University & Universite de Geneve.

Standardizing double-blind, placebo-controlled oral food challenges: American Academy of Allergy, Asthma & Immunology-European Academy of Allergy and Clinical Immunology PRACTALL consensus report

Abstract: Hugh A. Sampson, MD, Roy Gerth van Wijk, MD, Carsten Bindslev-Jensen, MD, PhD, Scott Sicherer, MD, Suzanne S. Teuber, MD, A. Wesley Burks, MD, Anthony E. J. Dubois, MD, Kirsten Beyer, MD, Philippe A. Eigenmann, MD, Jonathan M. Spergel, MD, PhD, Thomas Werfel, MD, and Vernon M. Chinchilli, PhD New York, NY, Rotterdam and Groningen, The Netherlands, Odense, Denmark, Davis, Calif, Chapel Hill, NC, Berlin and Hannover, Germany, Geneva, Switzerland, and Philadelphia and Hershey, Pa

The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?

Abstract: The role of the 3' untranslated region in posttranscriptional regulation of mRNA expression is being elucidated. Here we describe diseases arising from anomalies in this region, that affect the expression of one or more genes.

15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

Abstract: We identified 15q13.3 microdeletions encompassing the CHRNA7 gene in 12 of 1,223 individuals with idiopathic generalized epilepsy (IGE), which were not detected in 3,699 controls (joint P = 5.32 x 10(-8)). Most deletion carriers showed common IGE syndromes without other features previously associated with 15q13.3 microdeletions, such as intellectual disability, autism or schizophrenia. Our results indicate that 15q13.3 microdeletions constitute the most prevalent risk factor for common epilepsies identified to date.

Stellar evolution with rotation X: Wolf-Rayet star populations at solar metallicity

Abstract: We examine the properties of Wolf-Rayet (WR) stars predicted by models of rotating stars taking account of the new mass loss rates for O-type stars and WR stars (Vink et al. 2000. 2001; Nugis & Lamers 2000) and of the wind anisotropies induced by rotation. We find that the rotation velocities v of WR stars are modest, i.e. about 50 km s - 1 , not very dependent on the initial ν and masses. For the most massive stars, the evolution of ν is very strongly influenced by the values of the mass loss rates; below 12 M O . the evolution of rotation during the MS phase and later phases is dominated by the internal coupling. Massive stars with extreme rotation may skip the LBV phase. Models having a typical v for the O-type stars have WR lifetimes on the average two times longer than for non-rotating models. The increase of the WR lifetimes is mainly due to that of the H-rich eWNL phase. Rotation allows a transition WN/WC phase to be present for initial masses lower than 60 M O .. The durations of the other WR subphases are less affected by rotation. The mass threshold for forming WR stars is lowered from 37 to 22 M O . for typical rotation. The comparisons of the predicted number ratios WR/O, WN/WC and of the number of transition WN/WC stars show very good agreement with models with rotation, while this is not the case for models with the present-day mass loss rates and no rotation. As to the chemical abundances in WR stars, rotation brings only very small changes for WN stars, since they have equilibrium CNO values. However, WC stars with rotation have on average lower C/He and O/He ratios. The luminosity distribution of WC stars is also influenced by rotation.